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Anti-Melanogenic Effect from Submerged Mycelial Cultures of Ganoderma weberianum

Lai YJ, Hsu KD, Huang TJ, Hsieh CW, Chan YH, Cheng KC

Compounds from Lingzhi has been demonstrated the ability for inhibiting tyrosinase (a key enzyme in melanogenesis) activity. In this study, we investigated the anti-melanogenic activity from the submerged mycelial culture...
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Lignans with NADPH Oxidase 2 (NOX2)-inhibitory Activity from the Fruits of Schisandra chinensis

Park JM, Pel P, Chin YW, Lee MY

An isoform of NADPH oxidase (NOX), NOX2 is a superoxide-generating enzyme involved in diverse pathophysiological events. Although its potential as a therapeutic target has been validated, there is no clinically...
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Antimicrobial effect of Prunus mume extracts against cariogenic bacteria

Lee JS, Chung KH

OBJECTIVES: This study was conducted to determine whether Prunus mume extracts have an antimicrobial effect against Streptococcus mutans (S. mutans) and Streptococcus sobrinus (S. sobrinus). METHODS: The study used crushed and...
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Retreatability of two endodontic sealers, EndoSequence BC Sealer and AH Plus: a micro-computed tomographic comparison

Oltra E, Cox TC, LaCourse M, Johnson JD, Paranjpe A

OBJECTIVES: Recently, bioceramic sealers like EndoSequence BC Sealer (BC Sealer) have been introduced and are being used in endodontic practice. However, this sealer has limited research related to its retreatability....
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Studies on the Chemical Constituents from the Seeds of Zizyphus jujuba var. inermis

Lee NK, Shin HJ, Kim WS, In G, Han CK

This study analyzed the seeds of Zizyphus jujuba var. inermis commonly used as a remedy in traditional Chinese medicine, in order to determine its various biologically active compounds. Through process...
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Synthesis of ultrasound contrast agents: characteristics and size distribution analysis (secondary publication)

Lee HJ, Yoon TJ, Yoon YI

PURPOSE: The purpose of this study was to establish a method for ultrasound (US) contrast agent synthesis and to evaluate the characteristics of the synthesized US contrast agent. METHODS: A US...
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Antimicrobial, Antioxidant and Cytotoxic Activities of Dendropanax morbifera Léveille extract for mouthwash and denture cleaning solution

Kim RW, Lee SY, Kim SG, Heo YR, Son MK

PURPOSE: The purpose of this study was to analyze the antimicrobial, antioxidant activity and cytotoxicity of Dendropanax morbifera Léveille extract for assessing whether Dendropanax morbifera Léveille can be used for...
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Chemical Components from the Stems of Pueraria lobata and Their Tyrosinase Inhibitory Activity

Morgan AM, Jeon MN, Jeong MH, Yang SY, Kim YH

Phytochemical investigation of the stems of Pueraria lobata (Wild) Ohwi (Leguminosae), led to the isolation of eighteen known compounds: β-amyrone (1), (+)-pinoresinol (2), (+)-syringaresinol (3) (+)-syringaresinol-O-β-D-glucoside (4), (+)-lariciresinol (5), (-)-tuberosin...
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Quantitative HPLC Analysis and Extraction of 2,6-dimethoxy-1,4-benzoquinone from Ficus foveolata Stems

Meerungrueang W, Panichayupakaranant P

An antibacterial benzoquinone, 2,6-dimethoxy-1,4-benzoquinone, isolated from Ficus foveolata stems was used as a standard marker for establishment of quantitative HPLC analysis for the stem extracts of F. foveolata . The...
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Acute liver injury in two workers exposed to chloroform in cleanrooms: a case report

Kang YJ, Ahn J, Hwang YI

We report 2 cases of hepatotoxicity in cleanroom workers due to high retained chloroform air concentrations. The women, aged 34 and 41 years, who had been working in a medical...
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Screening of functional components derived from fresh water laver, Prasiola japonica, and its pharmacological properties

Seo DW, Kim HJ, Jang SK, Jun M, Joo SS

  • KMID: 1498926
  • J Biomed Res.
  • 2013 Jun;14(2):83-90.
The aim of the current study was to analyze the active ingredients and to screen the pharmacological properties of freshwater laver, Prasiola japonica, the only species grown in Korea. According...
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Inhibitory effects of Capsicum annuum L. water extracts on lipoprotein lipase activity in 3T3-L1 cells

Baek J, Lee J, Kim K, Kim T, Kim D, Kim C, Tsutomu K, Ochir S, Lee K, Park CH, Lee YJ, Choe M

  • KMID: 2391960
  • Nutr Res Pract.
  • 2013 Apr;7(2):96-102.
Obesity, an intractable metabolic disease, currently has no medical treatment without side effects, so studies have been actively carried out to find natural compounds that have anti-obesity activity with minimum...
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Synthesis of Ultrasound Contrast Agent: Characteristics and Size Distribution Analysis

Lee HJ, Yoon TJ, Yoon YI

  • KMID: 2096944
  • J Korean Soc Ultrasound Med.
  • 2013 Mar;32(1):59-65.
PURPOSE: The purpose of this study is to establish the methodology regarding synthesis of ultrasound contrast agent imaging, and to evaluate the characteristics of the synthesized ultrasound contrast agents, including...
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Attraction effect against Lycorma delicatula, antioxidant activity and local irritation test of Ailanthus altissima extract

Lee SJ, Park SC

  • KMID: 1790570
  • Korean J Vet Res.
  • 2013 Dec;53(4):231-237.
This study aimed to assess the attraction effect against Lycorma delicatula and antioxidant activity of hexane, chloroform, butanol and water fraction obtained from Ailanthus altissima methanol extract. The attraction effect...
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A Suspicious Case of Chloroform Induced Acute Toxic Hepatitis in Laboratory Worker

Lee DG, Lee CH, Jang KH, Chae HJ, Moon JD

  • KMID: 2075184
  • Korean J Occup Environ Med.
  • 2012 Sep;24(3):304-310.
OBJECTIVES: To report upon a case of toxic hepatitis in a worker exposed to chloroform. METHODS: A 28-year-old female who had worked as chemical analysis engineer in a laboratory using chloroform...
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The Chloroform Fraction of Carpinus tschonoskii Leaves Inhibits the Production of Inflammatory Mediators in HaCaT Keratinocytes and RAW264.7 Macrophages

Kang GJ, Kang NJ, Han SC, Koo DH, Kang HK, Yoo BS, Yoo ES

  • KMID: 1432309
  • Toxicol Res.
  • 2012 Dec;28(4):255-262.
Inflammation is the immune system's response to infection and injury-related disorders, and is related to pro-inflammatory factors (NO, PGE2, cytokines, etc.) produced by inflammatory cells. Atopic dermatitis (AD) is a...
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Carnoy's Solution Application for Patient Preliminarily Diagnosed with Keratocystic Odotogenic Tumor: Case Report

Choi ST, Kim TK, Leem DH, Baek JA, Shin HK, Ko SO

  • KMID: 2328056
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2012 Nov;34(6):498-504.
The odontogenic keratocyst (OKC) was originally classified as a developmental cyst, and OKC is histologically divided into orthokeratic and parakeratic types. According to revised histopathological classification of odontogenic tumors by...
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A Modified Extraction Method of Circulating Free DNA for Epidermal Growth Factor Receptor Mutation Analysis

Yuan H, Zhu ZZ, Lu Y, Liu F, Zhang W, Huang G, Zhu G, Jiang B

PURPOSE: Circulating free DNA (cfDNA) in plasma is promising to be a surrogate for tumor tissue DNA. However, not all epidermal growth factor receptor (EGFR) mutations in tumor tissue DNA...
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The Characteristics of the Appearance and Health Risks of Volatile Organic Compounds in Industrial (Pohang, Ulsan) and Non-Industrial (Gyeongju) Areas

Jung JH, Choi BW, Kim MH, Baek SO, Lee GW, Shon BH

  • KMID: 2380179
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012012.
OBJECTIVES: The aim of this study was to identify the health and environmental risk factors of air contaminants that influence environmental and respiratory diseases in Gyeongju, Pohang and Ulsan in...
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Isolation and characterization of fowl adenovirus serotype 4 from chickens with hydropericardium syndrome in Korea

Park HS, Lim IS, Kim SK, Kim TK, Yeo SG

  • KMID: 1991801
  • Korean J Vet Res.
  • 2011 Sep;51(3):209-216.
Four strains of fowl adenovirus (FAdV) were isolated from 4 flocks of broiler or layer chickens affected by hydropericardium syndrome in Korea. These FAdVs were classified as serotype 4 by...
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