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Anemia in children with chronic kidney disease

Park MJ, Cho MH

Chronic kidney disease (CKD) causes numerous changes that destabilize homeostasis, of which anemia is one of its important complications. Anemia significantly reduces the quality of life in children with CKD...
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Comprehensive review of membranoproliferative glomerulonephritis: spotlighting the latest advances in revised classification and treatment

Kim JY

Membranoproliferative glomerulonephritis (MPGN) is a complex group of renal diseases characterized by a specific pattern of glomerular injury that includes thickening of the capillary wall and mesangial expansion, leading to...
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Introducing the general management of glomerular disease from a pediatric perspective based on the updated KDIGO guidelines

Lim SH

In 2021, a new chapter on the general management of glomerulonephritis (GN) was added to the Kidney Disease: Improving Global Outcomes (KDIGO). It emphasizes the importance of early general management...
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An overview of Dent disease

Yang EM, Chang SH

Dent disease is a rare inherited kidney tubulopathy caused by mutations in either the CLCN5 (Dent disease 1) or OCRL1 (Dent disease 2) genes, and which is often underdiagnosed in...
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Tolvaptan: a possible preemptive treatment option in children with autosomal dominant polycystic kidney disease?

Beak HS, Cho MH

Tolvaptan is a highly selective vasopressin receptor 2 antagonist that regulates cyclic adenosine monophosphate levels to inhibit both epithelial cell proliferation and chloride ion excretion, two mechanisms known to induce...
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Nutcracker syndrome combined with immunoglobulin A nephropathy: two case reports

Ki SH, Son MH, Park E, Yim HE

Nutcracker syndrome (NCS) is a disease caused by compression of the left renal vein between the superior mesenteric artery and the abdominal aorta. Immunoglobulin A (IgA) nephropathy (IgAN) is characterized...
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A case of cystinuria with a heterozygous SLC3A1 mutation presenting with recurrent multiple renal stones in a 14-year-old boy

Cho HW, Son MH, Yim HE

Cystinuria, a genetically inherited disorder, is a rare cause of kidney stones. It is characterized by impaired transport of cystine and amino acids in the proximal renal tubule and the...
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Angiotensin receptor blocker induced fetopathy: two case reports and literature review

Joung J, Cho H

The administration of angiotensin type 2 receptor blockers (ARBs) during pregnancy is known to cause ARB fetopathy, including renal insufficiency. We aimed to analyze the outcomes of two patients who...
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Association of body weight and urinary tract infections during infancy: a nationwide comparative matched cohort study

Park PG, Kim JH, Ahn YH, Kang HG

Purpose: This article was to investigate the association between urinary tract infections (UTIs) and high weight status in infancy. Methods: We conducted a nationwide matched cohort study from January 2018 to...
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Renal artery stenosis presenting as congenital nephrotic syndrome with hyponatremic hypertensive syndrome in a 2-month-old infant: a case report

Kim D, Ahn YH, Kang HG, Kim JH, Lim SH

Here, we present the case of a 2-month-old male infant with hyponatremic hypertensive syndrome resulting from stenosis of the right proximal and mid-renal arteries. The patient exhibited nephrotic-range proteinuria, low...
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Nutcracker syndrome in children: review of symptom, diagnosis, and treatment

Kalantar DS, Park SJ, Shin JI

Renal nutcracker syndrome (NCS) is the entrapment of the left renal vein between the abdominal aorta and superior mesenteric artery. Although uncommon in pediatric patients, early diagnosis is crucial to...
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Efficacy and safety of losartan in childhood immunoglobulin A nephropathy: a prospective multicenter study

Hyun H, Ahn YH, Park E, Choi HJ, Han KH, Lee JW, Kim SY, Yang EM, Suh JS, Shin JI, Cho MH, Koo JW, Kim KH, Park HW, Ha IS, Cheong HI, Kang HG, Kim SH

Purpose: Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers (ARBs) are frequently employed to counteract the detrimental effects of proteinuria on glomerular diseases. However, the effects of ARBs remain poorly...
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Hypokalemia as a risk factor for prolonged QT interval and arrhythmia in inherited salt-losing tubulopathy

Kang SR, Ahn YH, Kang HG, Choi N

Purpose: To analyze electrocardiograms (ECGs) of patients with a salt-losing tubulopathy (SLT) and to determine the frequency and risk factors for long QT and arrhythmia. Methods: A total of 203 patients...
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