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METTL3 Affects Spinal Cord Neuronal Apoptosis by Regulating Bcl-2 m6A Modifications After Spinal Cord Injury

Guo S, Lin T, Chen G, Shangguan Z, Zhou L, Chen Z, Shi T, Chen D, Wang Z, Liu W

Objective: Spinal cord injury (SCI) is a severe type of neurological trauma. N6-methyladenosine (m6A) modification is one of the most common internal modifications of RNA. The role of METTL3, the...
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Nomogram for predicting overall survival in children with neuroblastoma based on SEER database

Liang SW, Chen G, Luo YG, Chen P, Gu JH, Xu QQ, Dang YW, Qin LT, Lu HP, Huang WT, Huang ZG, Gao L, Chen JB

Purpose: This study was performed to establish and validate a nomogram for predicting the overall survival in children with neuroblastoma. Methods: The latest clinical data of neuroblastoma in Surveillance, Epidemiology, and...
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What’s new in molecular genetic pathology 2022: immune checkpoint inhibitor biomarkers and select solid tumors

Tsang PC, Chen G

Predictive biomarker testing plays a critical role in targeted immuno-oncology, including the use of immune checkpoint inhibitors (ICI) for various solid tumors. Molecular advancements in cancers of the breast, kidney...
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Polysomnography and Neuropsychological Analysis of Patients With Post-Traumatic Stress Disorder Two Years After the COVID-19 Pandemic in Wuhan

Mei J, Xu Y, Gong X, Xu J, Chen G, Chen W, Wang Y, Kong Z, Wang Y, Yang Q

Objective We used polysomnography (PSG) monitoring and neuropsychological scales to explore the characteristics of coronavirus disease-2019 (COVID-19) patients diagnosed with post-traumatic stress disorder (PTSD) in Wuhan, two years after the...
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A Modified NHL-BFM-95 Regimen Produces Better Outcome ThanHyperCVAD in Adult Patients with T-Lymphoblastic Lymphoma,a Two-Institution Experience

Li C, Wuxiao ZJ, Chen X, Chen G, Lu Y, Xia Z, Liang Y, Wang H

Purpose Lymphoblastic lymphoma (LBL) is an invasive neoplasm of precursor T-cell or B-cell lineage. A broadly accepted standard treatment for adult LBL has not yet been defined. Materials and Methods To address this issue,...
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What’s new in molecular genetic pathology 2021: solid tumors and NGS panel selection

Chen G, Tsang PC

The linchpin of precision medicine is molecular genetic and genomic testing. Molecular biomarkers are important for establishing precise diagnoses and for predicting therapeutic responses that enable cancer patients to receive...
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Learning Curve of ROSA ONE Spine System for Transpedicular Screw Placement

Hsu BH, Liu HW, Lee KL, Lin MC, Chen G, Yu J, Chen CL, Su IC, Lin CM

Objective: The study investigated our institutional learning curve for the ROSA ONE spine system (ROSA) based on ROSA usage time. Methods: ROSA was designed to provide high accuracy for spinal pedicle...
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Discovery of a Fluoroquinolone-Resistant Serratia marcescens Clinical Isolate without Quinolone Resistance-Determining Region Mutations

Yang H, Chen G, Cheng J, Liu Y, Hu L, Ye Y, Li J

No abstract available.
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Evidence of two genetically different lymphotropic herpesviruses present among red deer, sambar, and milu herds in China

Zhu H, Liu H, Yu X, Zhang J, Jiang L, Chen G, Feng Z, Li Y, Feng T, Zhang X

Herpesvirus infections in Cervidae are a serious threat affecting some deer species worldwide. In our attempt to identify malignant catarrhal fever-associated herpesviruses in deer herds, ten gammaherpesviral DNA fragments were...
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Comparison of gastric-jejunum pouch anastomosis and Billroth-II reconstructions after distal gastrectomy: a propensity score matching analysis

Chen G, Cheng L, Liu L, Luo G, Li M, Wen Y, Wang T, Cao Y

Purpose: Our study aimed to make a propensity score matching (PSM) analysis on the clinical application of gastricjejunum pouch anastomosis (GJPA) and Billroth-II anastomosis after distal gastrectomy. Methods: We collected clinical...
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The independent effect of exercise on biopsy-proven non-alcoholic fatty liver disease: A systematic review

Chen G, Banini B, Do A, Lim JK

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Although previous studies have demonstrated that exercise independently reduces hepatic steatosis measured by imaging modalities...
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Excessive Startle with Novel GLRA1 Mutations in 4 Chinese Patients and a Literature Review of GLRA1-Related Hyperekplexia

Zhan F, Zhang C, Wang S, Zhu Z, Chen G, Zhao M, Cao L

Background and Purpose Hyperekplexia (HPX), a rare neurogenetic disorder, is classically characterized by neonatal hypertonia, exaggerated startle response provoked by the sudden external stimuli and followed by a shortly general stiffness....
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Anti-arthritic activity of D-carvone against complete Freund’s adjuvant-induced arthritis in rats through modulation of inflammatory cytokines

Chen G, Song Y, Ma F, Ma Y

Chronic joint pain due to loss of cartilage function, degradation of subchondral bone, and related conditions are common plights of an arthritis patient. Antioxidant compounds could solve the problems in arthritic...
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Effects of Acute Sacral Neuromodulation at Different Frequencies on Bladder Overactivity in Pigs

Li X, Liao L, Chen G, Wang Z, Deng H

PURPOSE: We investigated the effects of different stimulation frequencies on the inhibition of bladder overactivity by sacral neuromodulation (SNM) in pigs. METHODS: Implant-driven stimulators were used to stimulate the S3 spinal...
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Hookworm Infection Caused Acute Intestinal Bleeding Diagnosed by Capsule: A Case Report and Literature Review

Tan X, Cheng M, Zhang J, Chen G, Liu D, Liu Y, Liu H

Hookworm infections are rare causes of acute gastrointestinal bleeding. We report a middle aged man with primary nephrotic syndrome and pulmonary embolism. During the treatment with steroids and anticoagulants, the...
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Drainage procedure for pancreatolithiasis: re-examination of the pancreatic duct diameter standard

Chen G, You Y, Yan H, He J, Gong J, Wei S

Purpose: Pancreatic duct decompression relieves pancreatic duct stone (PDS)-associated abdominal pain, though a consensus indication for the drainage procedure of the main pancreatic duct (MPD) is lacking. Moreover, major prognostic...
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Molecular evolutionary analysis reveals Arctic-like rabies viruses evolved and dispersed independently in North and South Asia

Yu X, Zhu H, Bo Y, Li Y, Zhang J, Jiang L, Chen G, Zhang X, Wen Y

Background: Arctic-like (AL) lineages of rabies viruses (RABVs) remains endemic in some Arctic and Asia countries. However, their evolutionary dynamics are largely unappreciated. Objectives: We attempted to estimate the evolutionary history,...
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Changes in buccal facial depth of female patients after extraction and nonextraction orthodontic treatments: A preliminary study

Dai F, Yu J, Chen G, Xu T, Jiang R

OBJECTIVE: This study was performed to investigate buccal facial depth (BFD) changes after extraction and nonextraction orthodontic treatments in post-adolescent and adult female patients, and to explore possible influencing factors. METHODS:...
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PM2.5 in poultry houses synergizes with Pseudomonas aeruginosa to aggravate lung inflammation in mice through the NF-κB pathway

Li M, Wei X, Li Y, Feng T, Jiang L, Zhu H, Yu X, Tang J, Chen G, Zhang J, Zhang X

Background: High concentrations of particulate matter less than 2.5 μm in diameter (PM2.5) in poultry houses is an important cause of respiratory disease in animals and humans. Pseudomonas aeruginosa is...
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Effect of Occupational Health and Safety Management System on Work-Related Accident Rate and Differences of Occupational Health and Safety Management System Awareness between Managers in South Korea's Construction Industry

Yoon SJ, Lin HK, Chen G, Yi S, Choi J, Rui Z

  • KMID: 2317104
  • Saf Health Work.
  • 2013 Dec;4(4):201-209.
BACKGROUND: The study was conducted to investigate the current status of the occupational health and safety management system (OHSMS) in the construction industry and the effect of OHSMS on accident...
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