- Synergistic Effect of Interleukin-6 and Hyaluronic Acid on Cell Migration and ERK Activation in Human Keratinocytes
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Choi JH, Jun JH, Kim JH, Sung HJ, Lee JH
- KMID: 2151415
- J Korean Med Sci.
- 2014 Nov;29(Suppl 3):S210-S216.
- doi: 10.3346/jkms.2014.29.S3.S210
Wound healing is initiated and progressed by complex integrated process of cellular, physiologic, and biochemical events, such as inflammation, cell migration and proliferation. Interleukin 6 (IL-6) is a multifunctional cytokine,... -
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- Recombinant tetra-cell adhesion motifs supports adhesion, migration and proliferation of keratinocytes/fibroblasts, and promotes wound healing
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Jung MY, Thapa N, Kim JE, Yang JD, Cho BC, Kim IS
- KMID: 1090969
- Exp Mol Med.
- 2007 Oct;39(5):663-672.
An extracellular matrix protein plays an important role in skin wound healing. In the present study, we engineered a recombinant protein encompassing the 9th and 10th type III domains of... -
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- Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway
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Shin DH, Kim OH, Jun HS, Kang MK
- KMID: 1104802
- Exp Mol Med.
- 2008 Oct;40(5):486-494.
- doi: 10.3858/emm.2008.40.5.486
Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide), the major pungent ingredient of red pepper, has been reported to possess anti-carcinogenic and anti-mutagenic activities. In this study, the anti-migration activity of capsaicin on highly metastatic B16-F10... -
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- Inhibition of trichostatin A-induced antiangiogenesis by small-interfering RNA for thrombospondin-1
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Kang JH, Kim SA, Chang SY, Hong S, Hong KJ
- KMID: 1047092
- Exp Mol Med.
- 2007 Jun;39(3):402-411.
Expression of thrombospondin-1 (TSP-1), which is a known inhibitor of tumor growth and angiogenesis, is reciprocally regulated by positive regulators, such as VEGF. Additionally, trichostatin A (TSA) suppresses tumor progression... -
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- Tolfenamic Acid Inhibits the Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma: Involvement of p38-Mediated Down-Regulation of Slug
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Jittreetat T, Shin YS, Hwang HS, Lee BS, Kim YS, Sannikorn , Kim CH
- KMID: 2374076
- Yonsei Med J.
- 2016 May;57(3):588-598.
- doi: 10.3349/ymj.2016.57.3.588
PURPOSE: Tolfenamic acid (TA), a non-steroidal anti-inflammatory drug, is known to exhibit antitumor effects in various cancers apart from nasopharyngeal cancer (NPC). NPC exhibits high invasiveness, as well as metastatic... -
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- Lysophosphatidic acid induces cell migration through the selective activation of Akt1
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Kim EK, Yun SJ, Do KH, Kim MS, Cho M, Suh DS, Kim CD, Kim JH, Birnbaum M, Bae SS
- KMID: 1094124
- Exp Mol Med.
- 2008 Aug;40(4):445-452.
- doi: 10.3858/emm.2008.40.4.445
Akt plays pivotal roles in many physiological responses including growth, proliferation, survival, metabolism, and migration. In the current studies, we have evaluated the isoform-specific role of akt in lysophosphatidic acid... -
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- The effect of ferulic acid ethyl ester on leptin-induced proliferation and migration of aortic smooth muscle cells
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Tsai YC, Lee YM, Hsu CH, Leu SY, Chiang HY, Yen MH, Cheng PY
- KMID: 2155434
- Exp Mol Med.
- 2015 Aug;47(8):e180.
- doi: 10.1038/emm.2015.56
Leptin is a peptide hormone, which has a central role in the regulation of body weight; it also exerts many potentially atherogenic effects. Ferulic acid ethyl ester (FAEE) has been... -
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- Effect of Nitric Oxide on the Expression of Matrix Metalloproteinase and Its Association with Migration of Cultured Trabecular Meshwork Cells
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Kim JW
- KMID: 2363893
- Korean J Ophthalmol.
- 2016 Feb;30(1):66-75.
- doi: 10.3341/kjo.2016.30.1.66
PURPOSE: To determine the effect of exogenous nitric oxide (NO) on the migration of trabecular meshwork (TM) cells and its association with expression of matrix metalloproteinases (MMPs). METHODS: Primary human TM... -
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- STAT3 and ERK Signaling Pathways Are Implicated in the Invasion Activity by Oncostatin M through Induction of Matrix Metalloproteinases 2 and 9
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Ko HS, Park BJ, Choi SK, Kang HK, Kim A, Kim HS, Park IY, Shin JC
- KMID: 2374099
- Yonsei Med J.
- 2016 May;57(3):761-768.
- doi: 10.3349/ymj.2016.57.3.761
PURPOSE: Our previous studies have shown that oncostatin M (OSM) promotes trophoblast invasion activity through increased enzyme activity of matrix metalloproteinase (MMP)-2 and -9. We further investigated OSM-induced intracellular signaling... -
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- Comparative Effects of Non-Thermal Atmospheric Pressure Plasma on Migration and Invasion in Oral Squamous Cell Cancer, by Gas Type
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Kang SU, Seo SJ, Kim YS, Shin YS, Koh YW, Lee CM, Yang SS, Lee JS, Moon E, Kang H, Ryeo JB, Lee Y, Kim CH
- KMID: 2427114
- Yonsei Med J.
- 2017 Mar;58(2):272-281.
- doi: 10.3349/ymj.2017.58.2.272
PURPOSE: The fourth state of matter, plasma is known as an ionized gas with electrons, radicals and ions. The use of non-thermal plasma (NTP) in cancer research became possible because... -
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- Differential inhibition of endothelial cell proliferation and migration by urokinase subdomains: amino-terminal fragment and kringle domain
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Kim KS, Hong YK, Lee Y, Shin JY, Chang SI, Chung SI, Joe YA
- KMID: 1119342
- Exp Mol Med.
- 2003 Dec;35(6):578-585.
The serine protease urokinase-type plasminogen activator (uPA) is implicated in pericellular proteolysis in a variety of physiological and pathological processes including angiogenesis and tumor metastasis. The kringle domain of uPA... -
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- Anti-Proliferative Effects of Rutin on OLETF Rat Vascular Smooth Muscle Cells Stimulated by Glucose Variability
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Yu SH, Yu JM, Yoo HJ, Lee SJ, Kang DH, Cho YJ, Kim DM
- KMID: 2374042
- Yonsei Med J.
- 2016 Mar;57(2):373-381.
- doi: 10.3349/ymj.2016.57.2.373
PURPOSE: Proliferation of vascular smooth muscle cells (VSMCs) plays a crucial role in atherosclerosis. Rutin is a major representative of the flavonol subclass of flavonoids and has various pharmacological activities.... -
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