- RNA-sequencing Profiles of Cell Cycle–Related Genes Upregulated during the G2-Phase in Giardia lamblia
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Kim J, Shin MY, Park SJ
- KMID: 2448151
- Korean J Parasitol.
- 2019 Apr;57(2):185-189.
- doi: 10.3347/kjp.2019.57.2.185
To identify the component(s) involved in cell cycle control in the protozoan Giardia lamblia, cells arrested at the G1/S- or G2-phase by treatment with nocodazole and aphidicolin were prepared from... -
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- Molecular Aspects of Radiotherapy
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Park HJ
- KMID: 2200190
- J Lung Cancer.
- 2003 Mar;2(1):10-15.
When tumor cells are exposed to ionizing radiation, various and complicated molecular biological changes take place leading to cell death, mutation, and recovery from sublethal damage. It has been known... -
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- Expression of the D1 and E Cyclins in Carcinoma of the Cervix
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Kim YT, Lee JW, Kim JU, Cho NH
- KMID: 2269558
- Korean J Obstet Gynecol.
- 1998 Jun;41(6):1545-1551.
Multiple genetic changes occur during the evolution of normal cells into cancer cells. Recent work has identified another category of genes that, when mutated, increase genetic instability and accelerate cellular... -
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- Apoptosis and Cell Cycle Arrest in Two Human Breast Cancer Cell Lines by Dieckol Isolated from Ecklonia cava
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You SH, Kim JS, Kim YS
- KMID: 2434903
- J Breast Dis.
- 2018 Dec;6(2):39-45.
- doi: 10.14449/jbd.2018.6.2.45
PURPOSE: Dieckol, a phlorotannin compound isolated from Ecklonia cava, has been reported to have antioxidant, antiviral, anti-inflammatory, and anticancer properties. The purpose of this study was to investigate its anticancer... -
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- Down-regulation of Type I Collagen Gene Expression in Human Skin Fibroblasts by G1 Cell Cycle Arrest
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Park YD, Lee KS
- KMID: 1931117
- Korean J Dermatol.
- 2007 Apr;45(4):362-368.
BACKGROUND: Type I collagen is a major component of extracellular cellular matrix in tissue. It is synthesized by human skin fibroblasts. However, synthesis of type I collagen is markedly-decreased in... -
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- Cell cycle checkpoint control
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Murakami H, Okayama H
- KMID: 2128619
- Exp Mol Med.
- 1997 Mar;29(1):1-11.
Genetic instability is considered to be a major driving force of malignancy of cancer cells, and at least some of cancer-associated genetic instability is known to be caused by defects... -
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- MAD2 Expression in Ovarian Carcinoma: Different Expression Patterns and Levels among Various Types of Ovarian Carcinoma and Its Prognostic Significance in High-Grade Serous Carcinoma
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Park PE, Jeong JY, Kim SZ, Park JY
- KMID: 2141002
- Korean J Pathol.
- 2013 Oct;47(5):418-425.
BACKGROUND: Mitotic arrest deficiency protein 2 (MAD2) is a key component of spindle assembly checkpoint function, which mediates cell apoptosis through microtubule kinetics. Aberrant expression of MAD2 is believed to... -
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- Effects of p27 Overexpression on Head and Neck Squamous Cell Carcinoma Cell Lines
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Park SY, Lee DW
- KMID: 2030780
- Korean J Anat.
- 2005 Jun;38(3):227-234.
p27 is a cyclin dependent kinase inhibitor and plays an important role in negative regulation of the cell cycle. It has been revealed that down-regulation of p27 is frequently found... -
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- Apoptosis and Cell Cycle Arrest with EGF, TGF- a and TGF- 8 in Cervical Cancer Cell Lines
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Kim SY, Moon HS, Chung HW, Park HY, Kim SC
- KMID: 2305029
- Korean J Gynecol Oncol Colposc.
- 1999 Mar;10(1):58-66.
BACKGROUND: EGF and TGF-a are ligands for the EGF-receptor and act as mitogens for a variety of tissues. TGF-a, in particular, has been implicated as an autocrine growth factor for... -
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- p53 Prevents Immature Escaping from Cell Cycle G2 Checkpoint Arrest through Inhibiting cdk2-dependent NF-Y Phosphorylation
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Yun UJ, Park HD, Shin DY
- KMID: 2166051
- Cancer Res Treat.
- 2006 Dec;38(4):224-228.
PURPOSE: Recent studies have suggested that p53 regulates the G2 checkpoint in the cell cycle and this function is required for the maintenance of genomic integrity. In this study, we... -
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- A Natural Product, Chios Gum Mastic, Induces the Death of HL-60 Cells via Apoptosis and Cell Cycle Arrest
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Koo BC, Kim DH, Kim IR, Kim GC, Kwak HH, Park BS
- KMID: 2135279
- Int J Oral Biol.
- 2011 Mar;36(1):13-21.
Chios gum mastic (CGM) is produced from Pistiacia lentiscus L var chia, which grows only on Chios Island in Greece. CGM is a kind of resin extracted from the stem... -
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- Cellular Effects of Troglitazone on YD15 Tongue Carcinoma Cells
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Ta Thi L, Yoo H
- KMID: 2354198
- Int J Oral Biol.
- 2016 Sep;41(3):113-118.
- doi: 10.11620/IJOB.2016.41.3.113
An FDA approved drug for the treatment of type II diabetes, Troglitazone (TRO), a peroxisome proliferator–activated receptor gamma agonist, is withdrawn due to severe idiosyncratic hepatotoxicity. In the search for... -
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- Ethanol extract of Innotus obliquus (Chaga mushroom) induces G1 cell cycle arrest in HT-29 human colon cancer cells
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Lee HS, Kim EJ, Kim SH
- KMID: 2313817
- Nutr Res Pract.
- 2015 Apr;9(2):111-116.
- doi: 10.4162/nrp.2015.9.2.111
BACKGROUND/OBJECTIVES: Inonotus obliquus (I. obliquus, Chaga mushroom) has long been used as a folk medicine to treat cancer. In the present study, we examined whether or not ethanol extract of... -
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- Cellular Effect of Curcumin and Citral Combination on Breast Cancer Cells: Induction of Apoptosis and Cell Cycle Arrest
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Patel PB, Thakkar VR, Patel JS
- KMID: 2407569
- J Breast Cancer.
- 2015 Sep;18(3):225-234.
- doi: 10.4048/jbc.2015.18.3.225
PURPOSE: The unmanageable side effects caused by current chemotherapy regimens to treat cancer are an unresolved problem. Although many phytonutrients are useful as chemoprevention without side effects, their effects are... -
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- High-Dose 111In Induces G1 Cell Cycle Arrest and Cell Death in Rat Bone Marrow Mesenchymal Stem Cells
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Park BN, Shim W, Ahn YH, Lee JH, An YS, Yoon JK
- KMID: 2052002
- Nucl Med Mol Imaging.
- 2012 Jun;46(2):81-88.
PURPOSE: This study was performed to evaluate the effect of 111In-labeling on the cell growth, cycle and viability of bone marrow mesenchymal stem cells (BMSCs). METHODS: Rat BMSCs were labeled with... -
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- The Correlation between the Expression of CD99 and the Cell Cycle
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Yu CS, Chang MC, Oh SK
- KMID: 2145187
- J Korean Surg Soc.
- 2001 Oct;61(4):347-356.
PURPOSE: The cell cycle control system is necessary for the normal growth and differentiation of cells. The purposes of this study were to compare CD99 expression with a known... -
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- Effects of Replicative Senescence on the Cell Cycle Regulation in Human Gingival Fibroblasts
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Park YC, Yang DS, Kim JH, Kim HA, You YO, You HK, Shin HS
- KMID: 2045141
- J Korean Acad Periodontol.
- 2001 Mar;31(1):135-147.
- doi: 10.5051/jkape.2001.31.1.135
Gingival fibroblasts are major cellular component of gingiva. However, the molecular mechanisms of senescence of human gingival fibroblasts are unknown. Human fibroblasts undergo replicative senescence in vitro after a limited... -
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- Chios Gum Mastic Induces Cell Cycle Arrest and Apoptosis in Human Osteosarcoma Cells
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Min JH, Kim DK, Kwak HH, Kim GC, Lee SE, Kim IR, Kim CH, Park BS
- KMID: 1472476
- Korean J Anat.
- 2009 Dec;42(4):245-256.
Chios gum mastic (CGM) is a resin produced from the stem and leaves of Pistiacia lentiscus L var chia, a plant which grows only on Chios Island in Greece. CGM... -
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- Viriditoxin Induces G2/M Cell Cycle Arrest and Apoptosis in A549 Human Lung Cancer Cells
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Park JH, Noh TH, Wang H, Kim ND, Jung JH
- KMID: 2312911
- Nat Prod Sci.
- 2015 Dec;21(4):282-288.
- doi: 10.20307/nps.2015.21.4.282
Viriditoxin is a fungal metabolite isolated from Paecilomyces variotii, which was derived from the giant jellyfish Nemopilema nomurai. Viriditoxin was reported to inhibit polymerization of FtsZ, which is a key... -
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- Kaempferol induced the apoptosis via cell cycle arrest in human breast cancer MDA-MB-453 cells
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Choi EJ, Ahn WS
- KMID: 2139210
- Nutr Res Pract.
- 2008 Dec;2(4):322-325.
- doi: 10.4162/nrp.2008.2.4.322
The aim of present study was to investigate the effects of kaempferol on cellular proliferation and cell cycle arrest and explore the mechanism for these effects in human breast carcinoma... -
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