- Efflux Pump Inhibitor Carbonyl Cyanide-m-chlorophenylhydrazone (CCCP) Enhances Bacteriostatic Activity of Trimethoprim-sulfamethoxazole Against Clinical Stenotrophomonas maltophilia Isolates from Korea
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Rhee JY, Choi JY, Ko KS
- KMID: 2366863
- J Bacteriol Virol.
- 2016 Dec;46(4):185-192.
- doi: 10.4167/jbv.2016.46.4.185
Although trimethoprim-sulfamethoxazole (TMP-SXT) is considered the first-line therapy for Stenotrophomonas maltophilia infections, there is debate on the use of the bacteriostatic drug in serious infections, and recently, there has been... -
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- Spread of Efflux Pump Overexpressing-Mediated Fluoroquinolone Resistance and Multidrug Resistance in Pseudomonas aeruginosa by using an Efflux Pump Inhibitor
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Adabi M, Talebi-Taher M, Arbabi L, Afshar M, Fathizadeh S, Minaeian S, Moghadam-Maragheh N, Majidpour
- KMID: 2068993
- Infect Chemother.
- 2015 Jun;47(2):98-104.
- doi: 10.3947/ic.2015.47.2.98
BACKGROUND: Fluoroquinolone resistance in Pseudomonas aeruginosa may be due to efflux pump overexpression and/or target mutations. We designed this study to investigate the efflux pump mediated fluoroquinolone resistance and check... -
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- Salicylic Acid Reduces OmpF Expression, Rendering Salmonella enterica Serovar Typhimurium More Resistant to Cephalosporin Antibiotics
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Choi KM, Kim MH, Cai H, Lee YJ, Hong Y, Ryu PY
- KMID: 2458580
- Chonnam Med J.
- 2018 Jan;54(1):17-23.
- doi: 10.4068/cmj.2018.54.1.17
Salmonella enterica serovar Typhimurium is one of the most important bacterial pathogens causing diarrhea. The resistance of S. typhimurium to antimicrobial agents, which has recently been isolated from patients, is... -
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- Protective Effect of Ketamine on DNA Fragmentation in Astroglial Ischemic Model: Use of the TUNEL Assay to Determine Apoptosis
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Kim MH, Lee JJ
- KMID: 2237669
- Korean J Anesthesiol.
- 1998 May;34(5):915-919.
- doi: 10.4097/kjae.1998.34.5.915
BACKGROUND: Ketamine, a dissociative anesthetic, was known to be beneficial in reducing neuronal or astroglial damage by anoxic or ischemic insults. Detection of DNA fragments in situ using the terminal... -
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- The Effects of DTBNP on Intracellular Ca2+ Signaling in Cultured Bovine Aortic Endothelial Cells
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Park SJ, Kim BJ, Zhu MH, So I, Kim KW
- KMID: 2071617
- Korean J Physiol Pharmacol.
- 2005 Dec;9(6):341-346.
The mechanism underlying oxidant-induced intracellular Ca2+ ([Ca2+]i) increase was studied in cultured bovine aortic endothelial cells (BAECs) using fura-2 AM. In the presence of 2 mM extracellular Ca2+, the application... -
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- Buffering Contribution of Mitochondria to the [Ca2+]i Increase by Ca2+ Influx through Background Nonselective Cation Channels in Rabbit Aortic Endothelial Cells
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Kim YC, Lee SJ, Kim KW
- KMID: 2285307
- Korean J Physiol Pharmacol.
- 2005 Feb;9(1):29-35.
To prove the buffering contribution of mitochondria to the increase of intracellular Ca2+ level ([Ca2+]i) via background nonselective cation channel (background NSCC), we examined whether inhibition of mitochondria by protonophore... -
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- Assessment of Efflux Activity Using H33342 Accumulation in Tigecycline-Resistant Acinetobacter baumannii Clinical Isolates
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Kim CM, Choi IS, Jang SJ, Yun NR, Kim DM, Lim D, Ahn YJ, Kang SH, Park G, Moon DS
- KMID: 2398124
- Ann Clin Microbiol.
- 2017 Dec;20(4):90-96.
- doi: 10.5145/ACM.2017.20.4.90
BACKGROUND: Tigecycline resistance has emerged recently and has shown diverse mechanisms. The aim of this study was to assess the role of efflux activity in tigecycline resistance in 120 clinical... -
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- Glucose Oxidation and Production of Reactive Oxygen Species (ROS) in INS-1 Cells and Rat Islet Cells Exposed to High Glucose
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Yoon JS, Won KC, Lee HW
- KMID: 2177594
- J Korean Diabetes Assoc.
- 2006 Jul;30(4):246-253.
- doi: 10.4093/jkda.2006.30.4.246
BACKGROUND: Chronic exposure of pancreatic islets to supraphysiologic concentrations of glucose causes beta cell dysfunction that is a process known as glucose toxicity. It has been reported that hyperglycemia increases... -
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- Effect of Ketamine on Apoptosis by Energy Deprivation in Astroglioma Cells using Flow Cytometry System
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Choi SJ, Kim MH, Lim SW, Gwak MS
- KMID: 1781737
- J Korean Med Sci.
- 2005 Feb;20(1):113-120.
- doi: 10.3346/jkms.2005.20.1.113
Apoptosis is a programmed, physiologic mode of cell death that plays an important role in tissue homeostasis. As for the central nervous system, ischemic insults can induce pathophysiologic cascade of... -
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