- Calreticulin Exon 9 Mutations in Myeloproliferative Neoplasms
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Ha JS, Kim YK
- KMID: 2363143
- Ann Lab Med.
- 2015 Jan;35(1):22-27.
- doi: 10.3343/alm.2015.35.1.22
BACKGROUND: Calreticulin (CALR) mutations were recently discovered in patients with myeloproliferative neoplasms (MPNs). We studied the frequency and type of CALR mutations and their hematological characteristics. METHODS: A total of 168... -
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- Molecular and Biochemical Characterization of Opisthorchis viverrini Calreticulin
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Chaibangyang W, Geadkaew-Krenc A, Vichasri-Grams S, Tesana S, Grams R
- KMID: 2403715
- Korean J Parasitol.
- 2017 Dec;55(6):643-652.
- doi: 10.3347/kjp.2017.55.6.643
Calreticulin (CALR), a multifunctional protein thoroughly researched in mammals, comprises N-, P-, and C-domain and has roles in calcium homeostasis, chaperoning, clearance of apoptotic cells, cell adhesion, and also angiogenesis.... -
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- Straightforward Identification of Masked Polycythemia Vera Based on Proposed Revision of World Health Organization Diagnostic Criteria for BCR-ABL1-Negative Myeloproliferative Neoplasms
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Chu D, Cho YU, Jang S, Seo EJ, Park CJ
- KMID: 2363272
- Ann Lab Med.
- 2015 Nov;35(6):651-653.
- doi: 10.3343/alm.2015.35.6.651
No abstract available. -
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- Immunogenic Cell Death Induced by Ginsenoside Rg3: Significance in Dendritic Cell-based Anti-tumor Immunotherapy
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Son KJ, Choi KR, Lee SJ, Lee H
- KMID: 2154813
- Immune Netw.
- 2016 Feb;16(1):75-84.
- doi: 10.4110/in.2016.16.1.75
Cancer is one of the leading causes of morbidity and mortality worldwide; therefore there is a need to discover new therapeutic modules with improved efficacy and safety. Immune-(cell) therapy is... -
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- Chemotherapeutic Candidate Inducing Immunological Death of Human Tumor Cell Lines
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Oh SJ, Ryu CK, Choi I, Baek SY, Lee H
- KMID: 2150736
- Immune Netw.
- 2012 Apr;12(2):66-69.
- doi: 10.4110/in.2012.12.2.66
The immunological death induction by EY-6 on the human tumor cell lines was screened. Human colon carcinoma (HCT15, HCT116), gastric carcinoma (MKN74, SNU668), and myeloma (KMS20, KMS26, KMS34) cells were... -
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- IL-13 R110Q, a Naturally Occurring IL-13 Polymorphism, Confers Enhanced Functional Activity in Cultured Human Bronchial Smooth Muscle Cells
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He YF, Hua L, Bao YX, Liu QH, Chu Y, Fang DZ
- KMID: 2260281
- Allergy Asthma Immunol Res.
- 2013 Nov;5(6):377-382.
- doi: 10.4168/aair.2013.5.6.377
PURPOSE: Interleukin (IL)-13, a Th2-type cytokine, plays a pivotal role in the pathogenesis of asthma through its direct effects on airway smooth muscles. A naturally occurring IL-13 polymorphism, R110Q, is... -
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- Differences in Hematological and Clinical Features Between Essential Thrombocythemia Cases With JAK2- or CALR-Mutations
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Kubuki Y, Shide K, Kameda T, Yamaji T, Sekine M, Kamiunten , Akizuki K, Shimoda H, Tahira Y, Nakamura K, Abe H, Miike T, Iwakiri H, Tahara Y, Sueta M, Hashimoto , Yamamoto S, Hasuike S, Hidaka T, Nagata K, Kitanaka A, Shimoda K
- KMID: 2373635
- Ann Lab Med.
- 2017 Mar;37(2):159-161.
- doi: 10.3343/alm.2017.37.2.159
No abstract available. -
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- Incidence, Clinical Features, and Prognostic Impact of CALR Exon 9 Mutations in Essential Thrombocythemia and Primary Myelofibrosis: An Experience of a Single Tertiary Hospital in Korea
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Park SH, Kim SY, Lee SM, Yi J, Kim IS, Kim HH, Chang CL, Lee EY, Song MK, Shin HJ, Chung JS
- KMID: 2363184
- Ann Lab Med.
- 2015 Mar;35(2):233-237.
- doi: 10.3343/alm.2015.35.2.233
We evaluated the incidence, clinical characteristics, and prognostic impact of calreticulin (CALR) mutations in essential thrombocythemia (ET) and primary myelofibrosis (PMF) patients. In all, 48 ET and 14 PMF patients... -
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- Screening PCR Versus Sanger Sequencing: Detection of CALR Mutations in Patients With Thrombocytosis
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Jeong JH, Lee HT, Seo JY, Seo YH, Kim KH, Kim MJ, Lee JH, Park J, Hong JS, Park PW, Ahn JY
- KMID: 2373547
- Ann Lab Med.
- 2016 Jul;36(4):291-299.
- doi: 10.3343/alm.2016.36.4.291
BACKGROUND: Mutations in calreticulin (CALR) have been reported to be key markers in the molecular diagnosis of myeloid proliferative neoplasms. In most previous reports, CALR mutations were analyzed by using... -
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- Inhibition of Indoleamine 2,3-Dioxygenase Enhances the Therapeutic Efficacy of Immunogenic Chemotherapeutics in Breast Cancer
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Gao J, Deng F, Jia W
- KMID: 2450115
- J Breast Cancer.
- 2019 Jun;22(2):196-209.
- doi: 10.4048/jbc.2019.22.e23
PURPOSE: Breast cancer has become a major public health threat in the current society. Anthracycline doxorubicin (DOX) is a widely used drug in breast cancer chemotherapy. We aimed to investigate... -
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- JAK2 V617F, MPL, and CALR Mutations in Korean Patients with Essential Thrombocythemia and Primary Myelofibrosis
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Kim BH, Cho YU, Bae MH, Jang S, Seo EJ, Chi HS, Choi Y, Kim DY, Lee JH, Lee JH, Lee KH, Park YM, Lee JK, Park CJ
- KMID: 2164472
- J Korean Med Sci.
- 2015 Jul;30(7):882-888.
- doi: 10.3346/jkms.2015.30.7.882
Mutations in the calreticulin gene, CALR, have recently been discovered in subsets of patients with essential thrombocythemia (ET) or primary myelofibrosis (PMF). We investigated Korean patients with ET and PMF... -
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