- Hypermethylation of Tumor-related Genes in Genitourinary Cancer Cell Lines
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Chung WB, Hong SH, Kim JA, Sohn YK, Kim BW, Kim JW
- KMID: 648358
- J Korean Med Sci.
- 2001 Dec;16(6):756-761.
- doi: 10.3346/jkms.2001.16.6.756
Hypermethylation of CpG island is a common mechanism for the inactivation of tumor-related genes. In the present study, we analyzed 13 genitourinary cancer cell lines for aberrant DNA methylation of... -
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- DNA Methylation Patterns of Ulcer-Healing Genes Associated with the Normal Gastric Mucosa of Gastric Cancers
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Hong SJ, Oh JH, Jung YC, Kim YH, Kim SJ, Kang SJ, Seo EJ, Choi SW, Kang MI, Rhyu MG
- KMID: 1778036
- J Korean Med Sci.
- 2010 Mar;25(3):405-417.
- doi: 10.3346/jkms.2010.25.3.405
Recent evidence suggests that gastric mucosal injury induces adaptive changes in DNA methylation. In this study, the methylation status of the key tissue-specific genes in normal gastric mucosa of healthy... -
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- Hypoxia Induces Epithelial-Mesenchymal Transition in Follicular Thyroid Cancer: Involvement of Regulation of Twist by Hypoxia Inducible Factor-1alpha
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Yang YJ, Na HJ, Suh MJ, Ban MJ, Byeon HK, Kim WS, Kim JW, Choi EC, Kwon HJ, Chang JW, Koh YW
- KMID: 2345876
- Yonsei Med J.
- 2015 Nov;56(6):1503-1514.
- doi: 10.3349/ymj.2015.56.6.1503
PURPOSE: Although follicular thyroid cancer (FTC) has a relatively fair prognosis, distant metastasis sometimes results in poor prognosis and survival. There is little understanding of the mechanisms contributing to the... -
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- Cyclooxygenase-2 Expression Is Related to the Epithelial-to-Mesenchymal Transition in Human Colon Cancers
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Jang TJ, Jeon KH, Jung KH
- KMID: 1777097
- Yonsei Med J.
- 2009 Dec;50(6):818-824.
- doi: 10.3349/ymj.2009.50.6.818
PURPOSE: Down-regulation of E-cadherin is a hallmark of the epithelial-to-mesenchymal transition (EMT). EMT progression in cancer cells is associated with the loss of certain epithelial markers and the acquisition of... -
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- Significance of Preoperative Tissue Levels of Vascular-endothelial Cadherin, Liver-intestine Cadherin and Vascular Endothelial Growth Factor in Gastric Cancer
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Ryu KH, Shim KN, Jung SA, Yoo K, Joo YH, Lee JH
- KMID: 1775807
- Korean J Gastroenterol.
- 2012 Oct;60(4):229-241.
- doi: 10.4166/kjg.2012.60.4.229
BACKGROUND/AIMS: The aims of this study were to examine the expressions of endothelium specific VE-cadherin, intestine specific LI-cadherin, and vascular endothelial growth factor (VEGF), and to determine their relationships with... -
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