- Expression of Cyclin B1 and cdc2 in Nodal Non-Hodgkin's Lymphoma and its Prognostic Implications
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Jin YH, Park CK
- KMID: 1101545
- J Korean Med Sci.
- 2002 Jun;17(3):322-327.
- doi: 10.3346/jkms.2002.17.3.322
To investigate the role of cyclin B1 and cdc2 in the pathogenesis and progression of malignant lymphoma, 68 cases of nodal non-Hodgkin's lymphoma were examined about the expression of cyclin... -
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- p53 Prevents Immature Escaping from Cell Cycle G2 Checkpoint Arrest through Inhibiting cdk2-dependent NF-Y Phosphorylation
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Yun UJ, Park HD, Shin DY
- KMID: 2166051
- Cancer Res Treat.
- 2006 Dec;38(4):224-228.
PURPOSE: Recent studies have suggested that p53 regulates the G2 checkpoint in the cell cycle and this function is required for the maintenance of genomic integrity. In this study, we... -
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- Development of a Novel Nonradioisotopic Assay and Cdc25B Overexpression Cell Lines for Use in Screening for Cdc25B Inhibitors
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Ha GS, Lee CM, Kim CW
- KMID: 2419735
- Yonsei Med J.
- 2018 Oct;59(8):995-1003.
- doi: 10.3349/ymj.2018.59.8.995
PURPOSE: The cyclin-dependent kinase 1 (Cdk1) and cyclin B complex performs important roles in the transition from the G2 to M phase in the cell cycle through removal of inhibitory... -
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- BCL2 antagonist of cell death kinases, phosphatases, and ovarian cancer sensitivity to cisplatin
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Bansal N, Marchion D, Bicaku E, Xiong Y, Chen N, Stickles X, Sawah EA, Wenham RM, Apte SM, Gonzalez-Bosquet J, Judson PL, Hakam A, Lancaster
- KMID: 2177512
- J Gynecol Oncol.
- 2012 Jan;23(1):35-42.
- doi: 10.3802/jgo.2012.23.1.35
OBJECTIVE: The BCL2 family proteins are critical mediators of cellular apoptosis and, as such, have been implicated as determinants of cancer cell chemo-sensitivity. Recently, it has been demonstrated that the... -
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- Sorbus rufopilosa Extract Exhibits Antioxidant and Anticancer Activities by Inducing Cell Cycle Arrest and Apoptosis in Human Colon Adenocarcinoma HT29 Cells
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Oh YN, Jin S, Park HJ, Kwon HJ, Kim BW
- KMID: 2367562
- J Cancer Prev.
- 2016 Dec;21(4):249-256.
- doi: 10.15430/JCP.2016.21.4.249
BACKGROUND: Sorbus rufopilosa, a tsema rowan, is a species of the small ornamental trees in the genus Sorbus and the family Rosaceae found in East Asia. The bioactivities of S.... -
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- Changes in expression of cell cycle regulators after G1 progression upon repetitive thioacetamide treatment in rat liver
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Hong SH, Lee GD, Chung JY, Cho KS, Park SH, Kim IH, Jeong JS
- KMID: 755208
- Exp Mol Med.
- 2002 Nov;34(5):361-366.
Repetitive low dose thioacetamide (TA) treatment of hepatocytes was found to induce cells in G2 arrest. In the present study, an attempt was made to investigate alterations in expression of... -
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- Helicobacter pylori inhibited cell proliferation in human periodontal ligament fibroblasts through the Cdc25C/CDK1/cyclinB1 signaling cascade
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Li H, Liang D, Hu N, Dai X, He J, Zhuang H, Zhao W
- KMID: 2454084
- J Periodontal Implant Sci.
- 2019 Jun;49(3):138-147.
- doi: 10.5051/jpis.2019.49.3.138
PURPOSE: Several studies have shown that the oral cavity is a secondary location for Helicobacter pylori colonization and that H. pylori is associated with the severity of periodontitis. This study... -
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- Anti-cancer Activity of Osmanthus matsumuranus Extract by Inducing G2/M Arrest and Apoptosis in Human Hepatocellular Carcinoma Hep G2 Cells
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Jin S, Park HJ, Oh YN, Kwon HJ, Kim JH, Choi YH, Kim BW
- KMID: 2380876
- J Cancer Prev.
- 2015 Dec;20(4):241-249.
- doi: 10.15430/JCP.2015.20.4.241
BACKGROUND: Osmanthus matsumuranus, a species of Oleaceae, is found in East Asia and Southeast Asia. The bioactivities of O. matsumuranus have not yet been fully understood. Here, we studied on... -
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- Inhibitory Effect of Melanoma Differentiation Associated Gene-7/Interleukin-24 on Invasion In Vitro of Human Melanoma Cancer Cells
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Lin BW, Jiao ZL, Fan JF, Peng L, Li L, Zhao ZG, Ding XY, Li HJ
- KMID: 2158029
- J Korean Med Sci.
- 2013 Jun;28(6):833-839.
- doi: 10.3346/jkms.2013.28.6.833
The acquisition of metastasis potential is a critical point for malignant tumors. Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24) is a potential tumor suppress gene and frequently down-regulated in malignant tumors. It... -
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- Hypoxia induces Wee1 expression and attenuates hydrogen peroxide-induced endothelial damage in MS1 cells
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Hong KS, Kim HS, Kim SH, Lim DJ, Park JY, Kim SD
- KMID: 1058702
- Exp Mol Med.
- 2011 Dec;43(12):653-659.
- doi: 10.3858/emm.2011.43.12.074
In an oxygen-depleted environment, endothelial cells initiate an adaptive pattern of synthesis, which may enable them to survive hypoxic crises. Using high-resolution two-dimensional gel electrophoresis in conjunction with mass spectroscopy,... -
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- Prognostic Implications of Cyclin B1, p34cdc2, p27(Kip1) and p53 Expression in Gastric Cancer
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Kim DH
- KMID: 2158177
- Yonsei Med J.
- 2007 Aug;48(4):694-700.
- doi: 10.3349/ymj.2007.48.4.694
PURPOSE: Cell cycle progression is regulated by interactions of specific cyclins and cyclin dependent kinases (CDKs) at the G1-S and G2-M checkpoints and cell cycle deregulation plays a major role... -
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