- Genetic controls of Th17 cell differentiation and plasticity
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Dong C
- KMID: 991617
- Exp Mol Med.
- 2011 Jan;43(1):1-6.
- doi: 10.3858/emm.2011.43.1.007
CD4+ T lymphocytes play a major role in regulation of adaptive immunity. Upon activation, naive T cells differentiate into different functional subsets. In addition to the classical Th1 and Th2... -
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- Differential Cell Analysis and Lymphocyte Subset Analysis in Bronchoalveolar Lavage Fluid from Patients with Miliary Tuberculosis
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Kim JE, Seol HY, Cho WH, Kim KU, Jeon DS, Park HK, Kim YS, Lee MK, Park SK
- KMID: 2319310
- Tuberc Respir Dis.
- 2010 Apr;68(4):218-225.
BACKGROUND: Bronchoalveolar lavage (BAL) is a useful technique to recover lower airway fluid and cells involved in many respiratory diseases. Miliary tuberculosis is potentially lethal, but the clinical manifestations are... -
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- Maintenance of CD8+T-cell anergy by CD4+CD25+ regulatory T cells in chronic graft-versus-host disease
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Kim J, Kim HJ, Choi WS, Nam SH, Cho HR, Kwon B
- KMID: 1098083
- Exp Mol Med.
- 2006 Oct;38(5):494-501.
In a murine model of systemic lupus erythematosus (SLE)-like chronic graft-versus-host disease (cGVHD), donor CD8+T cells rapidly fall into anergy to host cells, while donor CD4+T cells hyperactivate B cells... -
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- Peripheral blood lymphocyte subsets in patients with stomach cancer
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Hong WS, Min YI, Son YS, Hong SI
- KMID: 1054339
- J Korean Med Sci.
- 1995 Jun;10(3):164-168.
- doi: 10.3346/jkms.1995.10.3.164
The present study was conducted in order to investigate the immunologic alterations alongside the numerical changes in peripheral blood lymphocytes(PBL) and their subsets in stomach cancer patients. Lymphocyte surface markers... -
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- Quantitation of T-lymphocyte Subsets Using the CELL-DYN Sapphire Automated Haematology Analyser
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Kim J, Ryu S, Lim J, Kwon G, Koo S
- KMID: 2200452
- J Lab Med Qual Assur.
- 2014 Mar;36(1):39-47.
BACKGROUND: Quantitative analysis of T-lymphocyte subsets is used to assess immune competency. Traditionally, T-lymphocyte subset analysis has been performed using flow cytometry, which requires complex instrumentation and relatively skilled manual... -
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- In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1
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La S, Kim E, Kwon B
- KMID: 1056231
- Exp Mol Med.
- 2005 Jun;37(3):193-198.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive... -
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- Kaposi's Sarcoma Associated with Gastric Involvement
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Lee BG, Lee MH, Kim NI, Haw CR
- KMID: 2362131
- Ann Dermatol.
- 1989 Jul;1(2):114-118.
- doi: 10.5021/ad.1989.1.2.114
We report a case of classic Kaposi's sarcoma (KS) in a 67-year-old man, who had multiple cutaneous lesions of the feet and left hand as well as an internal involvement... -
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- A Case of Pulmonary Cryptococcosis with Non-Small Cell Lung Cancer in Idiopathic CD4+ T-Lymphocytopenia
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Ahn IS, Kim HG, Ryu JS, Kim L, Kwak SM, Lee HL, Yoon YH, Cho JH
- KMID: 2158131
- Yonsei Med J.
- 2005 Feb;46(1):173-176.
- doi: 10.3349/ymj.2005.46.1.173
Cryptococcus neoformans commonly causes opportunistic infections in immunocompromised patients, especially in patients with AIDS. CD4+ T-lymphocytopenia in AIDS indicates an increased risk of opportunistic infection and a decline in immunological... -
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- Serosal Cavities Contain Two Populations of Innate-like integrin α4highCD4+ T Cells, Integrin α4β1+α6β1+α4β7− and α4β1+α6β1−α4β7+ Cells
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Yang JI, Park C, Kho I, Lee S, Suh KS, Kim TJ
- KMID: 2400625
- Immune Netw.
- 2017 Dec;17(6):392-401.
- doi: 10.4110/in.2017.17.6.392
We previously reported peritoneal innate-like integrin α4 (CD49d)highCD4+ T cells that provided help for B-1a cells. Here we analyzed the expression of various integrin chains on the peritoneal and pleural... -
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- Two-signal blockade with anti-CD45RB and anti-CD154 monoclonal antibodies inhibits graft rejection via CD4-dependent mechanisms in allogeneic skin transplantation
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Kim EY, Lee EN, Lee J, Park HJ, Chang CY, Jung DY, Choi SY, Lee SK, Joh JW, Kim SJ
- KMID: 1094154
- Exp Mol Med.
- 2006 Jun;38(3):284-294.
Blockade of signal 1 or 2 for T-cell activation by the use of anti-CD45RB and anti-CD154 monoclonal antibodies (mAb) (two-signal blockade) has been proven effective in preventing or delaying graft... -
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- The Expression of Programmed Death-1 in Circulating CD4+ and CD8+ T Cells during Hepatitis B Virus Infection Progression and Its Correlation with Clinical Baseline Characteristics
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Xu P, Chen YJ, Chen H, Zhu XY, Song HF, Cao LJ, Wang XF
- KMID: 1774547
- Gut Liver.
- 2014 Mar;8(2):186-195.
BACKGROUND/AIMS: Programmed death-1 (PD-1) expression was investigated in CD4+ and CD8+ T cells from hepatitis B virus (HBV)-infected patients at the chronic hepatitis B (CHB) infection, liver cirrhosis (LC), and... -
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- A simple human immunodeficiency virus vector system for selective infection of CD4(+) cells and inducible expression of foreign genes
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Kim YS
- KMID: 2045605
- Exp Mol Med.
- 1997 Jun;29(2):103-110.
The alteration of T lymphocyte functions as a consequence of human immunodeficiency virus (HIV) infection is a potential target for the genetic treatment of the acquired immunodeficiency syndrome (AIDS). One... -
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- Unusual Histology of Eosinophilic Myenteric Ganglionitis: A Case Report
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Lee H, Kang D, Kim H, Cho B, Jang J
- KMID: 2392599
- J Pathol Transl Med.
- 2017 May;51(3):320-324.
- doi: 10.4132/jptm.2016.09.07
Eosinophilic myenteric ganglionitis is a disorder characterized by infiltration of the Auerbach myenteric plexus by eosinophils. As a cause of chronic intestinal pseudo-obstruction (CIPO), eosinophilic myenteric ganglionitis has been rarely... -
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- Apoptosis of T Lymphocytes Isolated from Peripheral Blood of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
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Lim SC, Ju JY, Chi SY, Ban HJ, Kwon YS, Oh IJ, Kim KS, Kim YI, Kim YC
- KMID: 1727989
- Yonsei Med J.
- 2011 Jul;52(4):581-587.
- doi: 10.3349/ymj.2011.52.4.581
PURPOSE: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of the airways and progressive destruction of lung parenchyma. Apoptosis is critical for the maintenance of normal tissue homeostasis... -
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- The Effects of Fungi on the Activation of Monocyte Derived Dendritic Cells and Its Impact on Priming Th Polarization
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Shin SH, Ye MK, Han BD
- KMID: 2132003
- J Rhinol.
- 2010 Nov;17(2):112-117.
BACKGROUND AND OBJECTIVES: The mucosal immune response depends on the surveillance network established by dendritic cells (DC) localized within the respiratory epithelium. Fungi have been increasingly recognized as important pathogens... -
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- Expression of 4-1BB and 4-1BBL in thymocytes during thymus regeneration
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Kim YM, Kim HK, Kim HJ, Lee HW, Ju SA, Choi BK, Kwon BS, Kim BS, Kim JB, Lim YT, Yoon S
- KMID: 1099866
- Exp Mol Med.
- 2009 Dec;41(12):896-911.
- doi: 10.3858/emm.2009.41.12.095
4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily, is a major costimulatory receptor that is rapidly expressed on the surface of CD4+ and CD8+ T cells after... -
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- Prevention of chronic graft-versus-host disease by stimulation with glucocorticoid-induced TNF receptor
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Kim J, Choi WS, Kim HJ, Kwon B
- KMID: 1105281
- Exp Mol Med.
- 2006 Feb;38(1):94-99.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive... -
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- Constitutive expression of 4-1BB on T cells enhances CD4+ T cell responses
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Kim J, Choi SP, La S, Seo JS, Kim KK, Nam SH, Kwon B
- KMID: 1119332
- Exp Mol Med.
- 2003 Dec;35(6):509-517.
4-1BB, a transmembrane molecule, member of the tumor necrosis factor receptor superfamily, is an important costimulatory molecule in the immune response, plays a key role in the clonal expansion and... -
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- Unique features of bovine lymphocytes exposed to a staphylococcal enterotoxin
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Park YH, Lee SU, Ferens WA, Samuels S, Davis WC, Fox LK, Ahn JS, Seo KS, Chang BS, Hwang SY, Bohach GA
- KMID: 1089907
- J Vet Sci.
- 2006 Sep;7(3):233-239.
- doi: 10.4142/jvs.2006.7.3.233
We previously demonstrated that stimulation of bovine peripheral blood mononuclear cells (PBMCs) with staphylococcal enterotoxin C (SEC), led to an inversion of the CD4(+):CD8(+) T cell ratio and generation of... -
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- Antitumor immunity induced by tumor cells engineered to express a membrane-bound form of IL-2
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Chang MR, Lee WH, Choi JW, Park SO, Paik SG, Kim YS
- KMID: 1056237
- Exp Mol Med.
- 2005 Jun;37(3):240-249.
Transduction of cytokine gene into tumor cells is a promising method of tumor therapy, but the value is limited by accompanying side effects. To focus antitumor immune response to tumor... -
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