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Distinctive bone regeneration of calvarial defects using biphasic calcium phosphate supplemented ultraviolet-crosslinked collagen membrane

Hong I, Khalid AW, Pae HC, Cha JK, Lee JS, Paik JW, Jung UW, Choi SH

PURPOSE: To overcome several drawbacks of chemically-crosslinked collagen membranes, modification processes such as ultraviolet (UV) crosslinking and the addition of biphasic calcium phosphate (BCP) to collagen membranes have been introduced....
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Horizontal ridge augmentation using guided bone regeneration technique in two young patients with localized alveolar ridge defect: A case report

Kim DH, Jeong SN

Lateral ridge augmentation using guided bone regeneration technique is a frequently performed procedure that is used for restoring localized bone defects after extraction. In particular, demineralized bovine bone material and...
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Guided bone regeneration in peri-implant defects using a 1:1 mixture of cancellous and cortical freeze-dried bone allograft: A randomized controlled trial

Lee WP, Park DY, Lee KW, Yang KI, Kim BO, Yu SJ

The results of guided bone regeneration (GBR) in peri-implant defects using anorganic bovine bone (ABB) were compared with those using a 1:1 mixture of cancellous and cortical freeze-dried bone allograft...
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Clinical Use of Mesenchymal Stem Cells in Bone Regeneration

Park CW, Lim SJ, Park YS

Owing to the recent advances in biological knowledge on stem cells, many efforts are being made to apply them to clinical practice. Although mesenchymal stem cells were first found in...
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Clinical effect of porous titanium mesh with cross-linked collagen membrane for guided bone regeneration

Jung SH, Chang HY, You HK, Pi SH

Titanium mesh, a barrier membrane, has excellent mechanical properties and space maintaining ability. However, one of its disadvantages is that soft tissue over the membrane could be interposed through the...
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Stimulatory Effects of KPR-A148 on Osteoblast Differentiation and Bone Regeneration

Lim S, Kim JA, Lee T, Lee D, Nam SH, Lim J, Park EK

BACKGROUND: Xanthine derivatives have been used to treat a variety of medical conditions including respiratory disease and neural degeneration. However, few studies have reported their effects on bone regeneration. Therefore,...
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Use of platelet-rich fibrin and natural bone regeneration in regenerative surgery

Jee YJ

No abstract available.
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Assessment of clinical and radiographic outcomes of guided bone regeneration with dehydrothermally cross-linked collagen membrane around peri-implant dehiscence defects: Results from a 3-year randomized clinical trial

Lee JH, Park SH, Kim DH, Jung UW

The objective of this study was to determine the clinical and radiographic efficacy of dehydrothermally (DHT) cross-linked collagen membrane in the treatment of peri-implant dehiscence defects through a 3-year randomized...
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Spontaneous bone regeneration after surgical extraction of a horizontally impacted mandibular third molar: a retrospective panoramic radiograph analysis

Kim E, Eo MY, Nguyen TT, Yang HJ, Myoung H, Kim SM

BACKGROUND: The mandibular third molar (M3) is typically the last permanent tooth to erupt because of insufficient space and thick soft tissues covering its surface. Problems such as alveolar bone...
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Bone Regeneration Using Block-type Deproteinized Porcine Bone Mineral with Collagen Membrane Using 3,4-Dihydroxyphenylalanine as Bone Adhesive

Kang JH, Pae HC, Cha JK, Lee JS, Paik JW, Jung UW, Choi SH

PURPOSE: The purpose of this study was to assess the adhesiveness and cytotoxicity of 3, 4-dihydroxyphenylalanine (DOPA), and to evaluate the role of collagen membrane with DOPA in the guided...
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Determination of the optimal diabetes duration for bone regeneration experiments in an alloxan-induced diabetic rabbit calvarial defect model

Jeong SH, Jung BH, Yoo KY, Um HS, Chang BS, Lee JK, Choi WY

PURPOSE: The purpose of this study was to evaluate the optimal diabetes duration for bone regeneration experiments in an alloxan monohydrate (ALX)–induced diabetic rabbit calvarial defect model by evaluating the...
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Biomimetic characteristics of mussel adhesive protein-loaded collagen membrane in guided bone regeneration of rabbit calvarial defects

Song WK, Kang JH, Cha JK, Lee JS, Paik JW, Jung UW, Kim BH, Choi SH

PURPOSE: The aim of the present study was to evaluate the biocompatibility and barrier function of mussel adhesive protein (MAP)-loaded collagen membranes in guided bone regeneration (GBR). METHODS: Eight male New...
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Bone regeneration with umbilical cord blood mesenchymal stem cells in femoral defects of ovariectomized rats

Hong B, Lee S, Shin N, Ko Y, Kim D, Lee J, Lee W

OBJECTIVES: Current treatments for osteoporosis were prevention of progression, yet it has been questionable in the stimulation of bone growth. The mesenchymal stem cells (MSCs) treatment for osteoporosis aims to...
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Mesenchymal Stem Cell Therapy for Bone Regeneration

Jin YZ, Lee JH

Mesenchymal stem cells (MSCs) have been used in clinic for approximately 20 years. During this period, various new populations of MSCs have been found or manipulated. However, their characters and...
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Wicking Property of Graft Material Enhanced Bone Regeneration in the Ovariectomized Rat Model

Kim S, Ahn T, Han MH, Bae C, Oh DS

BACKGROUND: Recruitment and homing cells into graft materials from host tissue is crucial for bone regeneration. METHODS: Highly porous, multi-level structural, hydroxyapatite bone void filler (HA-BVF) have been investigated to restore...
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Guided bone regeneration using K-incision technique

Cho YD, Ku Y

PURPOSE: The present study describes 3 patients with chronic periodontitis and consequent vertical resorption of the alveolar ridge who were treated using implant-based restoration with guided bone regeneration (GBR). METHODS: After...
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Effect of herbal extracts on bone regeneration in a rat calvaria defect model and screening system

Lee DH, Kim IK, Cho HY, Seo JH, Jang JM, Kim J

OBJECTIVES: The aim of this study was to evaluate the effects of herbal extracts on bone regeneration. Two known samples were screened. MATERIALS AND METHODS: We previously established a rat calvaria...
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Trans-differentiation via Epigenetics: A New Paradigm in the Bone Regeneration

Cho YD, Ryoo HM

In regenerative medicine, growing cells or tissues in the laboratory is necessary when damaged cells can not heal by themselves. Acquisition of the required cells from the patient's own cells...
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Mesenchymal Stromal Cells from the Maternal Segment of Human Umbilical Cord is Ideal for Bone Regeneration in Allogenic Setting

Lim J, Razi ZR, Law JX, Nawi AM, Idrus RB, Chin TG, Mustangin , Ng MH

Umbilical cord (UC) is a discarded product from the operating theatre and a ready source of mesenchymal stromal cells (MSCs). MSCs from UC express both embryonic and adult mesenchymal stem...
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Development of an experimental model for radiation-induced inhibition of cranial bone regeneration

Jung HM, Lee JE, Lee SJ, Lee JT, Kwon TY, Kwon TG

BACKGROUND: Radiation therapy is widely employed in the treatment of head and neck cancer. Adverse effects of therapeutic irradiation include delayed bone healing after dental extraction or impaired bone regeneration...
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