J Korean Assoc Oral Maxillofac Surg.  2002 Aug;28(4):256-263.

The Effect On Guided Bone Regeneration Of The Chitosan Membrane

• Moon JS
• Park YJ
• Park JW
• Lee YC
• Cho BO
• Ahn BK

Abstract

Using the rat's skull, the study on the biodegradability and guided bone regeneration of the chitosan membrane was performed. The results are as follows: 1. The biodegradability of the chitosan membrane could not be confirmed, but after 12 weeks, this membrane did not yet break into small pieces and there was no specific local tissue reaction. 2. It was not certain whether the pore size of this membrane was affected on osteoblastic activity. 3. After 6 weeks, the bony defect area of rat's skull was not completely filled, but on high magnification it showed that the osteoclasts and the osteoblasts were observed in the regenerating area. In conclusion, the chitosan membrane developed in this study was fit for guided bone regeneration.

Keyword

Chitosan membrane; Guided bone regeneration

MeSH Terms

Bone Regeneration*
Chitosan*
Membranes*
Osteoblasts
Osteoclasts
Skull
Chitosan