- Bicuculline Induced Epileptiform Activity
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Choi BJ
- KMID: 2177013
- J Korean Child Neurol Soc.
- 2005 May;13(1):57-62.
PURPOSE: The goal of this study was to investigate the effects of bicuculline(BIC) on the excitability of visual cortex, observe the induction of epileptiform activity and define the characteristics of... -
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- Influence of Glutamate on the Circling Movement In the Unilateral Substantia Nigra-lesioned Rats
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Han MI, Chung YC, Eun HB
- KMID: 2340101
- J Korean Neuropsychiatr Assoc.
- 1997 Sep;36(5):919-926.
The aim of this study was to examine the effects of various concentrations of glutamate(10(-8), 10(-6) and 10(-4) M) on the circling movement induced by apomorphine in the unilateral substantia... -
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- Suppression by Microinjection of Bicuculline into Brain Stem Nuclei of Dorsal Horn Neuron Responsiveness in Neuropathic Rats
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Leem JW, Choi Y, Lee JH, Nam TS, Paik KS
- KMID: 2104785
- J Korean Pain Soc.
- 1998 May;11(1):23-29.
BACKGROUND: The present study was conducted to investigate effects of mieroinjection of bicuculline, GABA-A receptor antagonist, into the brain stem nuclei on the dorsal horn neuron responsiveness in rats with an experimental... -
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- A Study on the Neurotransmitters Acting on the Medullospinal Tract Cells Related to the Cardiovascular Activity
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Seo DM, Kim SJ, Lim WI, Kim J, Kim CW
- KMID: 2115187
- Korean J Thorac Cardiovasc Surg.
- 1998 May;31(5):441-450.
The medullospinal tract cells are known to play an important role in the control of the cardiovascular activities. To clarify the modes of action of the neurotransmitters on these cells,... -
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- Effect of GABA on the Contractility of Canine Trachealis Muscle
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Koo CH, Kwon OC, Choi EM, Lee KY, Kim WJ
- KMID: 2352247
- Yeungnam Univ J Med.
- 1994 Dec;11(2):314-322.
- doi: 10.12701/yujm.1994.11.2.314
This study aimed to investigate the existence of GABA receptor and the mechanisms of action of GABA and diazepam of the trachealis muscle isolated from dog. Horizontal muscle strips of... -
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- Effect of Potassium, Bicuculline and CNQX on Epileptiform Activity Induced by Pilocarpine in the Rat Visual Cortex Slice
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Choi BJ, Kim YI
- KMID: 1636113
- J Korean Neurol Assoc.
- 2006 Dec;24(6):571-576.
BACKGROUND: The purpose of this study was to investigate the effect of potassium, bicuculline (BIC) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) on epileptiform activity induced by pilocarpine in the rat visual cortex slices.... -
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- Effects of taurine on generalized seizure activity in the rat thalamocortical slice
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Yang SG, Lee IK, Lee CJ
- KMID: 2066109
- J Korean Neurol Assoc.
- 1997 Dec;15(6):1236-1246.
Rat thalamocortical slices maintain synoptic connections between thalamus and cortex. When perfused with low Mg++-ACSF, thalamocortical slices exhibited two main types of spontaneous bursting activity. One is monotonic burst of... -
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- Studies on the Changes of Blood Pressure and Heart Rate by Intracerebroventricular Bicuculline in Rabbits
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Lee JG, Kang SS, Lee JH, Kim JK
- KMID: 1690979
- J Korean Neurosurg Soc.
- 1992 May;21(5):553-560.
To elucidate the role of CNS GABA ergic system in the regulation of cardiovascular function, the effects of intracerebroventricular(icv) bicuculline(BIC), a selective GABAA antagonist, on blood pressure and heart rate... -
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- The Effects of GABA-receptor Antagonists on the Spinal Cord Stimulation-induced Antinociception in Cats
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Youn MJ, Jung SJ, Park JM, Lee SC, Kim J, Kim NS
- KMID: 2031954
- Korean J Anesthesiol.
- 2002 Mar;42(3):383-392.
- doi: 10.4097/kjae.2002.42.3.383
BACKGROUND: Spinal cord stimulation (SCS) is a clinical off spring of the gate-control theory and known as an effective treatment for pain from a neurogenic origin. The prolonged... -
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- Interhemispheric Modulation on Afferent Sensory Transmission to the Ventral Posterior Medial Thalamus by Contralateral Primary Somatosensory Cortex
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Jung SC, Choi IS, Cho JH, Kim JH, Bae YC, Lee MG, Shin HC, Choi BJ
- KMID: 2285296
- Korean J Physiol Pharmacol.
- 2004 Jun;8(3):129-132.
Single unit responses of the ventral posterior medial (VPM) thalamic neurons to stimulation were monitored in anesthetized rats during activation of contralateral primary somatosensory (SI) cortex by GABA antagonist. The... -
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- GABAB Receptor Modulation on the Antinociception of Intrathecal Sildenafil in the Rat Formalin Test
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Kim WM, Yoon MH, Lee HG, Han YG, Kim YO, Huang LJ, Cui JH
- KMID: 2278049
- Korean J Pain.
- 2007 Dec;20(2):106-110.
- doi: 10.3344/kjp.2007.20.2.106
BACKGROUND: A phosphodiesterase 5 inhibitor, sildenafil, has been effective against nociception. Several lines of evidence have demonstrated the role of the GABAergic pathway in the modulation of nociception. The impact... -
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- Effect of intrathecal glycine and related amino acids on the allodynia and hyperalgesic action of strychnine or bicuculline in mice
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Lim ES, Lee IO
- KMID: 2031786
- Korean J Anesthesiol.
- 2010 Jan;58(1):76-86.
- doi: 10.4097/kjae.2010.58.1.76
BACKGROUND: The intrathecal (IT) administration of glycine or GABAA receptor antagonist result in a touch evoked allodynia through disinhibition in the spinal cord. Glycine is an inhibitory neurotransmitter that appears... -
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- Effect of diazepam on the oxytocin induced contraction of the isolated rat uterus
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Park YK, Lee SH, Kwon OC, Ha JH, Lee KY, Kim WJ
- KMID: 2377592
- Yeungnam Univ J Med.
- 1992 Dec;9(2):359-381.
- doi: 10.12701/yujm.1992.9.2.359
This study was designed to investigate the effect of diazepam on the spontaneous contraction and oxytocin induced contraction of the isolated rat uterus. Female rat (Sprague-Dawley) pretreated with oophorectomy and... -
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- Intraocular Injection of Muscimol Induces Illusory Motion Reversal in Goldfish
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Lee SY, Jung CS
- KMID: 2285383
- Korean J Physiol Pharmacol.
- 2009 Dec;13(6):469-473.
- doi: 10.4196/kjpp.2009.13.6.469
Induced activation of the gamma-aminobutyric acidA (GABA(A)) receptor in the retina of goldfish caused the fish to rotate in the opposite direction to that of the spinning pattern during an... -
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- Changes of CA1 Excitability in Rats after Prenatal Methylazoxymethanol Treatment
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Jang SY, Choi IS, Cho JH, Jang IS, Lee MG, Choi BJ
- KMID: 1512936
- Korean J Physiol Pharmacol.
- 2006 Feb;10(1):13-17.
Experimentally induced cortical disorganization exhibits many anatomical features which are characteristic of cortical malformations in children with early-onset epilepsy. We used an immunocytochemical technique and extracellular field potential recordings from... -
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- Combined Application of Bicuculline and 4-Aminopyridine-Induced Epileptiform Activity are Resistant to Conventional Anticonvulsants and AMPA in Young Rat Visual Cortex
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Choi BJ
- KMID: 1816508
- J Korean Epilepsy Soc.
- 2006 Jun;10(1):35-40.
PURPOSE: The goal of the present study was to find out whether blockade of GABAergic synaptic transmission by bicuculline (BIC) in the presence of 4-aminopyridine (4-AP) would lead to expression... -
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- Effect of GABA on the contratility of small intestine isolated from rat
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Huh JY, Kwon OC, Ha JH, Lee KY, Kim WJ
- KMID: 2377364
- Yeungnam Univ J Med.
- 1991 Dec;8(2):95-105.
- doi: 10.12701/yujm.1991.8.2.95
This study was designed to investigate the effect of GABA and related substances on the spontaneous contraction of rat small intestine. The rats (Sprague-Dawley), weighing 200-250g, were sacrificed by cervical... -
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- The Effect of Treatment with Intrathecal Ginsenosides in a Rat Model of Postoperative Pain
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Shin DJ, Yoon MH, Lee HG, Kim WM, Park BY, Kim YO, Huang LJ, Cui JH
- KMID: 2278048
- Korean J Pain.
- 2007 Dec;20(2):100-105.
- doi: 10.3344/kjp.2007.20.2.100
BACKGROUND: Ginseng has been used to manage various types of pain in folk medicine. This study characterized the effect of treatment with intrathecal ginsenosides, the active components of ginseng in... -
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- Morphine-induced Modulation of Nociceptive Spinal Dorsal Horn Neuronal Activities after Formalin-induced Inflammatory Pain
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Park JM, Li KW, Jung SJ, Kim J, Kim SJ
- KMID: 2285313
- Korean J Physiol Pharmacol.
- 2005 Apr;9(2):77-86.
In this study, we examined the morphine-induced modulation of the nociceptive spinal dorsal horn neuronal activities before and after formalin-induced inflammatory pain. Intradermal injection of formalin induced time-dependent changes in... -
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- The antinociceptive effect of artemisinin on the inflammatory pain and role of GABAergic and opioidergic systems
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Dehkordi F, Kaboutari , Zendehdel , Javdani M
- KMID: 2455611
- Korean J Pain.
- 2019 Jul;32(3):160-167.
- doi: 10.3344/kjp.2019.32.3.160
BACKGROUND: Pain is a complex mechanism which involves different systems, including the opioidergic and GABAergic systems. Due to the side effects of chemical analgesic agents, attention toward natural agents have... -
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