- A Public-Private Collaboration Model for Treatment Intervention to Improve Outcomes in Patients with Tuberculosis in the Private Sector
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Kim HJ, Bai GH, Kang MK, Kim SJ, Lee JK, Cho SI, Lew WJ
- KMID: 1846397
- Tuberc Respir Dis.
- 2009 May;66(5):349-357.
- doi: 10.4046/trd.2009.66.5.349
BACKGROUND: The treatment success rates in patients with tuberculosis are known to be lower in the private sector compared to the public sector. To improve treatment outcomes in the private... -
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- Evaluation of the Broth Microdilution Method Using 2,3-Diphenyl-5-thienyl-(2)-tetrazolium Chloride for Rapidly Growing Mycobacteria Susceptibility Testing
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Lee SM, Kim JM, Jeong J, Park YK, Bai GH, Lee EY, Lee MK, Chang CL
- KMID: 1713281
- J Korean Med Sci.
- 2007 Oct;22(5):784-790.
- doi: 10.3346/jkms.2007.22.5.784
As the incidence of nontuberculous mycobacterial infection has been increasing recently in Korea, the importance of drug susceptibility test for clinical isolates of mycobacteria has become larger. In this study... -
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- Pulmonary Disease Caused by Mycobacterium xenopi: The First Case in Korea
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Park HY, Koh WJ, Kwon OJ, Lee NY, Shim YM, Park YK, Bai GH, Mun HS, Kim BJ
- KMID: 1122628
- Yonsei Med J.
- 2007 Oct;48(5):871-875.
- doi: 10.3349/ymj.2007.48.5.871
Mycobacterium xenopi is a nontuberculous mycobacterium (NTM) that rarely causes pulmonary disease in Asia. Here we describe the first case of M. xenopi pulmonary disease in Korea. A 66-year-old man... -
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- Drug Resistance Rates of Mycobacterium tuberculosis at a Private Referral Center in Korea
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Choi JC, Lim SY, Suh GY, Chung MP, Kim H, Kwon OJ, Lee NY, Park YK, Bai GH, Koh WJ
- KMID: 1127086
- J Korean Med Sci.
- 2007 Aug;22(4):677-681.
- doi: 10.3346/jkms.2007.22.4.677
The goals of this study were to identify first-line drug resistance in new and previously treated tuberculosis (TB) cases and to determine risk factors for multidrugresistant TB (MDR-TB) at a... -
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- The Interval Between Initiation of Anti-tuberculosis Treatment in Patients with Culture-positive Pulmonary Tuberculosis and Receipt of Drug-susceptibility Test Results
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Joh JS, Lee CH, Lee JE, Park YK, Bai GH, Kim EC, Han SK, Shim YS, Yim JJ
- KMID: 1713225
- J Korean Med Sci.
- 2007 Feb;22(1):26-29.
- doi: 10.3346/jkms.2007.22.1.26
Although mycobacterial culture and the subsequent drug-susceptibility test (DST) for anti-tuberculosis (TB) drugs take several months to complete using solid media, there are no reports on the turnaround times of... -
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- Evaluation of Automatic Acid-Fast Bacilli Stainer AT-2000F
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Kim SY, Yang EK, Kim YJ, Lee SM, Lee EY, Park YK, Bai GH, Chang CL
- KMID: 2224723
- Korean J Clin Microbiol.
- 2006 Oct;9(2):115-118.
BACKGROUND: Sputum smear microscopy is rapid, economic, and useful to detect patients with transmittable tuberculosis, albeit laborious. We aimed to evaluate the usefulness of an automated acid-fast bacilli stainer, which... -
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- The Current Status of Multidrug-resistant Tuberculosis in Korea
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Kim BJ, Lee IH, Lee DH, Bai GH, Kong SJ, Lee SH, Moon HR, Lee KR, Lee JY, Park SK
- KMID: 1719365
- Tuberc Respir Dis.
- 2006 Apr;60(4):404-411.
- doi: 10.4046/trd.2006.60.4.404
PURPOSE: Multidrug-resistant tuberculosis (MDR-TB) is an emerging threat to human beings. However, there is little data on the current status of MDR-TB in Korea. This study investigated the current status... -
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- Analysis of DNA fingerprints of Mycobacterium Tuberculosis Isolates from Patients Registered at Health Center in Gyeonggi Province in 2004
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Park YK, Kang HY, Lim JG, Ha JS, Cho JO, Lee KC, Choi HS, Choi YH, Sheen SS, Bai GH
- KMID: 2318843
- Tuberc Respir Dis.
- 2006 Mar;60(3):290-296.
BACKGROUND: IS6110 DNA fingerprint is a very useful tool for investigating the transmission of tuberculosis. The aim of this study was to identify the epidemiological situations within a given area... -
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- Investigation of the Growth Rate Change in Recombinant BCG which was cloned Mycobacterium tuberculosis Adenylate Kinase Mutation Gene or Human Muscle-type Adenylate Kinase Synthetic Gene
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Lee SH, Kim HJ, Park YK, Bai GH
- KMID: 2318818
- Tuberc Respir Dis.
- 2006 Feb;60(2):187-193.
BACKGROUND: Normal cell proliferation and viability is strongly depends on the availability of metabolic energy and the maintenance of the appropriate adenylate-nucleotide pools. Hypothetically, changes in adenylate kinase (AK) expression... -
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- A Trend in Acquired Drug Resistances of Tuberculosis Patients Registered in Health Centers from 1981 to 2004
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Chang CL, Lee EY, Park SK, Jeong SH, Park YK, Choi YW, Kim HJ, Lew WJ, Bai GH
- KMID: 2318747
- Tuberc Respir Dis.
- 2005 Dec;59(6):619-624.
BACKGROUND: The drug resistance rate in tuberculosis patients with history of chemotherapy is an important indicator of for evaluation of appropriateness of treatment regimens and compliance of patients. This... -
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- Mycobacterium kansasii Pulmonary Diseases in Korea
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Yim JJ, Park YK, Lew WJ, Bai GH, Han SK, Shim YS
- KMID: 2157744
- J Korean Med Sci.
- 2005 Dec;20(6):957-960.
- doi: 10.3346/jkms.2005.20.6.957
Mycobacterium kansasii is one of the most common cause of pulmonary diseases due to nontuberculous mycobacteria. We investigated the changing in the number of isolation of M. kansasii and the... -
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- Implication of embB Gene Mutation in Ethambutol-Susceptible Clinical Isolates of Mycobacterium tuberculosis
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Park YK, Shin S, Kim SJ, Koh WJ, Kwon OJ, Kim BJ, Kook YH, Cho SN, Lew WJ, Bai GH
- KMID: 2318663
- Tuberc Respir Dis.
- 2005 Sep;59(3):266-271.
BACKGROUND: Ethambutol(EMB) is one of the first-line drugs included in short-course anti-tuberculosis therapy. The point mutations in embB gene have been speculated to be associated EMB resistance. However, detection of... -
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- The Proportion of Rifabutin-susceptible Strains among Rifampicin- resistant Isolates and Its Specific rpoB Mutations
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Lew WJ, Park YK, Kim HJ, Chang C, Bai GH, Kim SK
- KMID: 2318662
- Tuberc Respir Dis.
- 2005 Sep;59(3):257-265.
BACKGROUND: Rifabutin (ansamycin) is a spiro-piperidyl rifamycin, which is highly active against Mycobacterium tuberculosis. It has been found that some clinical isolates of tubercle bacilli that are resistant to rifampicin... -
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- Cross Resistance of Fluoroquinolone Drugs on gyrA Gene Mutation in Mycobacterium tuberculosis
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Park YK, Park CH, Koh WJ, Kwon OJ, Kim BJ, Kook YH, Cho SN, Chang CH, Bai GH
- KMID: 2318661
- Tuberc Respir Dis.
- 2005 Sep;59(3):250-256.
BACKGROUND: Fluoroquinolone drugs are an important anti-tuberculous agent for the treatment of multi-drug resistant tuberculosis. However, many drugs belonging to the fluoroquinolones have different cross resistance to each other. METHODS: Sixty-three... -
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- Protective Efficacy of Recombinant Proteins Adenylate Kinase, Nucleoside Diphosphate Kinase, and Heat-Shock Protein 70 against Mycobacterium tuberculosis Infection in Mice
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Lee SH, Lee EG, Kim SY, Cho SN, Park YK, Bai GH
- KMID: 2318536
- Tuberc Respir Dis.
- 2005 Feb;58(2):142-151.
BACKGROUND: Priming and boosting vaccination strategy has been widely explored for new vaccine development against tuberculosis. As an effort to identify other vaccine candidates, this study was initiated to evaluate... -
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- Detection of embB Gene Mutation of Mycobacterium tuberculosis by Reverse Hybridization Assay
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Park YK, Yu HK, Park CH, Ryu SW, Lee SH, Shim MS, Lew WJ, Koh WJ, Kwon OJ, Cho SN, Bai GH
- KMID: 2318534
- Tuberc Respir Dis.
- 2005 Feb;58(2):129-134.
BACKGROUND: Ethambutol (EMB) is one of important first-line drug in the treatment of tuberculosis. Molecular techniques to detect embB gene mutations have been considered as an method to define the... -
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- Multi-center Study on Cost Effectiveness of Anti-Tuberculosis Drug Susceptibility Test
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Jeong SH, Lee DD, Choi JC, Kim S, Shin JH, Jeong J, Lee EY, Oh SH, Bai GH, Chang CL
- KMID: 2285097
- Infect Chemother.
- 2005 Feb;37(1):16-21.
BACKGROUND: The anti-mycobacterial susceptibility test is performed on only a small percentage of clinical isolates in Korea. The aim of this study is to propose an anti-mycobacterial susceptibility testing scheme,... -
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- Treatment of Mycobacterium avium Complex (MAC) Pulmonary Disease
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Koh WJ, Kwon OJ, Kang EH, Suh GY, Chung MP, Kim H, Chung MJ, Kim TS, Lee KS, Lee NY, Park YK, Bai GH
- KMID: 1656512
- Tuberc Respir Dis.
- 2004 Sep;57(3):234-241.
- doi: 10.4046/trd.2004.57.3.234
BACKGROUND: There has been a gradual increase in the number of newly diagnosed cases of Mycobacterium avium complex (MAC) pulmonary disease. However, the optimal therapeutic regimen for the disease has... -
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- Construction of Recombinant BCGs Overexpressing Antigen 85 Complex and Their Protective Efficacy against Mycobacterium tuberculosis Infection in a Mouse Model
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Lee SH, Jeon BY, Park YG, Lee HY, Cho SN, Kim HJ, Bai GH
- KMID: 2132493
- Tuberc Respir Dis.
- 2004 Aug;57(2):125-131.
- doi: 10.4046/trd.2004.57.2.125
Tuberculosis (TB) remains an enormous global health problem, and a new vaccine against TB more potent than the current inadequate BCG vaccine is urgently needed. We constructed three recombinant Mycobacterium... -
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- Molecular Taxonomic Survey of Mycobacteria Clinical Isolates from Patients in Jeju Island by rpoB Gene Based Molecular Biological Methods
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Kim H, Kim SH, Bai GH, Park YG, Cha CY, Kook YH, Kim BJ
- KMID: 2055003
- J Bacteriol Virol.
- 2004 Jun;34(2):113-119.
The rpoB gene based sequencing analysis enabled not only the detection of rifampin resistant Mycobacterium tuberculosis, but also the differentiation of species in the genus Mycobacterium. In the present study,... -
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