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Rapid identification of mycobacterium avium and mycobacterium intracellulare by the amplification of rRNA sequences

Bai GH

  • KMID: 1688015
  • J Korean Soc Microbiol.
  • 1992 Oct;27(5):443-448.
No abstract available.
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Antituberculosis Drug Resistance in Korea , 1998-1999

Bai GH, Park YK, Lee HK, Kim SJ

  • KMID: 2099360
  • J Korean Soc Microbiol.
  • 2000 Oct;35(5):368-368.
No Abstract Available.
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Clinically isolated mycobacteria other than mycobacterium tuberculosis from 1980 to 1990 in korea

Bai GH, Park KS, Kim SJ

  • KMID: 1688054
  • J Korean Soc Microbiol.
  • 1993 Feb;28(1):1-5.
No abstract available.
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Efficiency of different primers in polymerase chain reacion to detect mycobacterium tuberculosis in clinical specimens

Shim MS, Lee SY, Cho SH, Park YK, Bai GH, Kim SJ

  • KMID: 2099265
  • J Korean Soc Microbiol.
  • 1993 Oct;28(5):391-395.
No abstract available.
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The Relationship between Isoniazid Resistance and 463 CodonMutation of katG Gne in Mycobacterium Tuberculosis

Park YK, Shim MS, Cho SH, Bai GH, Kim SJ

  • KMID: 2317967
  • Tuberc Respir Dis.
  • 1996 Feb;43(1):8-13.
BACKGROUND: The 463 codon mutation of katG gene has been reported as an useful marker for the detection of isoniazid(INH) resistant strains of M. tuberculosis. This study aimed to elucidate...
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HIV - 1 p24 Expression in BCG and the Immunogenicity of Recombinant BCG in Experimental Animals

Cho SH, Myoung HJ, Jeong HR, Bai GH, Kim SJ, Bae YS

  • KMID: 1548228
  • Korean J Immunol.
  • 1997 Jun;19(2):289-300.
HIV-1 p24 was cloned into multiple cloning site of pMV261, extrachromosomal expression vectors carrying BCG replication origin and BCG-specific heat-shock promoter, and then introduced into BCG and E. coli. Western...
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Rapid Drug Susceptibility Testing for Isoniazid and Rifampicin by Reverse Hybridization Assay

Park YK, Yu HK, Ryu SW, Bai GH

  • KMID: 2318439
  • Tuberc Respir Dis.
  • 2003 Nov;55(5):440-448.
BACKGROUND: Development of rapid drug susceptibility testing provides the opportunity for rapid identification of individuals with drug resistant tubercle bacilli, allowing selection of appropriate therapeutic regimens. METHODS: A total of 502...
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Identification of Mycobacterium avium complex ( MAC ) clinical Strains to a Species Level by Sequencing and PCR - SSCP Analysis of rpoB DNA

Kim BJ, Lee SH, Lee KH, Park CK, Choi MS, Kim IS, Choi SB, Hwang ES, Cha CY, Kim SJ, Bai GH, Kook YH

  • KMID: 1543612
  • J Korean Soc Microbiol.
  • 1999 Oct;34(5):491-500.
A recent study showed that comparative sequence analysis of rpoB DNAs could reveal natural relationships in genus Mycobacterium [J Clin Microbiol. 37 (6). 1999]. rpoB DNAs showed interspecies variation and...
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Molecular Taxonomic Survey of Mycobacteria Clinical Isolates from Patients in Jeju Island by rpoB Gene Based Molecular Biological Methods

Kim H, Kim SH, Bai GH, Park YG, Cha CY, Kook YH, Kim BJ

  • KMID: 2055003
  • J Bacteriol Virol.
  • 2004 Jun;34(2):113-119.
The rpoB gene based sequencing analysis enabled not only the detection of rifampin resistant Mycobacterium tuberculosis, but also the differentiation of species in the genus Mycobacterium. In the present study,...
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IS6110 based DNA Fingerprinting of Mycobacterium tuberculosis Isolated from The Nationwide Tuberculosis Prevalence Survey in 1995

Kim SJ, Park YK, Cho SH, Bai GH, Kim Y

  • KMID: 2099296
  • J Korean Soc Microbiol.
  • 1998 Oct;33(5):475-484.
One hundred and thirty-eight strains of Mycobacterium tuberculosis isolated from the 7th nationwide tuberculosis prevalence survey in 1995 were subjected to the restriction fragment length polymorphism (RFLP) analysis using IS6110...
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Investigation of the Growth Rate Change in Recombinant BCG which was cloned Mycobacterium tuberculosis Adenylate Kinase Mutation Gene or Human Muscle-type Adenylate Kinase Synthetic Gene

Lee SH, Kim HJ, Park YK, Bai GH

  • KMID: 2318818
  • Tuberc Respir Dis.
  • 2006 Feb;60(2):187-193.
BACKGROUND: Normal cell proliferation and viability is strongly depends on the availability of metabolic energy and the maintenance of the appropriate adenylate-nucleotide pools. Hypothetically, changes in adenylate kinase (AK) expression...
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Construction of Recombinant BCGs Overexpressing Antigen 85 Complex and Their Protective Efficacy against Mycobacterium tuberculosis Infection in a Mouse Model

Lee SH, Jeon BY, Park YG, Lee HY, Cho SN, Kim HJ, Bai GH

Tuberculosis (TB) remains an enormous global health problem, and a new vaccine against TB more potent than the current inadequate BCG vaccine is urgently needed. We constructed three recombinant Mycobacterium...
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Mycobacterium kansasii Pulmonary Diseases in Korea

Yim JJ, Park YK, Lew WJ, Bai GH, Han SK, Shim YS

Mycobacterium kansasii is one of the most common cause of pulmonary diseases due to nontuberculous mycobacteria. We investigated the changing in the number of isolation of M. kansasii and the...
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Prevention of Virus - induced Diabetes by Single Immunization with Recombinant BCG in SJL/J Male Mice

Cho SH, Choe YK, Bai GH, Kim SJ, Bae YS, Choi BK, Hyun BH, Lee HH

  • KMID: 1550775
  • Korean J Immunol.
  • 1999 Sep;21(3):259-269.
D variant of encephalomyocarditis (EMC-D) virus causes diabetes in susceptible mice by direct infection and cytolysis of pancreatic beta cells. cDNA covering the major outer capsid protein (VP1) of EMC-D...
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Analysis of the Cell Lysate Proteome of a Korean Mycobacterium tuberculosis Isolate K01 with H37Rv and H37Ra Strains

Ryu SW, Park SC, Bang MN, Han SS, Park YK, Park SN, Shim YS, Kang S, Bai GH

  • KMID: 2055002
  • J Bacteriol Virol.
  • 2004 Jun;34(2):107-112.
Despite recent economic prosperity, Korea still has high prevalence of tuberculosis. Molecular biologic characterization of Korean Mycobacterium tuberculosis strains might provide a deeper understanding of the forces contributing to the...
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Identification of Fastidious Mycobacteria other than M. tuberculosis ( MOTT ) by Comparative Sequence Analysis of rpoB and 16S rDNA

Kim BJ, Im SI, Kim YW, Bai GH, Kim SJ, Lee KH, Cha CY, Kook YH

  • KMID: 1572904
  • J Bacteriol Virol.
  • 2002 Mar;32(1):39-45.
Conventional tests for the identification of mycobacteria may frequently result in erroneous identification and underestimate the diversity within the genus Mycobacterium. However, this problem can be overcome by molecular approach...
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A Case Report of Three Patients with Nontuberculous Mycobacterial Pulmonary Disease Caused by Mycobacterium kansasii

Koh WJ, Kwon OJ, Suh GY, Chung MP, Kim H, Lee NY, Kim TS, Lee KS, Park EM, Park YK, Bai GH

  • KMID: 2318418
  • Tuberc Respir Dis.
  • 2003 Apr;54(4):459-466.
Mycobacterium kansasii is the second most common cause of nontuberculous mycobacterial pulmonary disease in Western countries and Japan. The clinical and radiological features of pulmonary disease caused by M. kansasii...
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Differentiation of Mycobacterium avium Complex Isolated in Korea by DT1-BT6 PCR

Kim BJ, Byun KH, Bai GH, Kim SJ, Lee KH, Hwang ES, Cha CY, Kook YH

  • KMID: 1572902
  • J Bacteriol Virol.
  • 2002 Mar;32(1):33-38.
Recently, selective PCR method using DT1 and DT6 sequences was introduced to identify and differentiate the Mycobacterium avium complex (MAC) into M. intracellulare and M. avium. We applied this method...
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The Proportion of Rifabutin-susceptible Strains among Rifampicin- resistant Isolates and Its Specific rpoB Mutations

Lew WJ, Park YK, Kim HJ, Chang C, Bai GH, Kim SK

  • KMID: 2318662
  • Tuberc Respir Dis.
  • 2005 Sep;59(3):257-265.
BACKGROUND: Rifabutin (ansamycin) is a spiro-piperidyl rifamycin, which is highly active against Mycobacterium tuberculosis. It has been found that some clinical isolates of tubercle bacilli that are resistant to rifampicin...
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Detection of embB Gene Mutation of Mycobacterium tuberculosis by Reverse Hybridization Assay

Park YK, Yu HK, Park CH, Ryu SW, Lee SH, Shim MS, Lew WJ, Koh WJ, Kwon OJ, Cho SN, Bai GH

  • KMID: 2318534
  • Tuberc Respir Dis.
  • 2005 Feb;58(2):129-134.
BACKGROUND: Ethambutol (EMB) is one of important first-line drug in the treatment of tuberculosis. Molecular techniques to detect embB gene mutations have been considered as an method to define the...
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