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Elevated Aurora Kinase A Protein Expression in Diabetic Skin Tissue

Cho MK, An JM, Kim CH, Kang SG

BACKGROUND: Aurora kinase A (Aurora-A) plays an important role in the regulation of mitosis and cytokinesis. Dysregulated Aurora-A leads to mitotic faults and results in pathological conditions. No studies on...
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Characterization of the Indirubin Derivative LDD970 as a Small Molecule Aurora Kinase A Inhibitor in Human Colorectal Cancer Cells

Ndolo KM, Park KR, Lee HJ, Yoon KB, Kim YC, Han SY

Aurora kinase A plays an essential role in mitosis including chromosome separation and cytokinesis. Aberrant expression and activity of Aurora kinase A is associated with numerous malignancies including colorectal cancer...
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A study of APin-protein interactions using protein microarray

Park JC, Park SH, Kim HJ, Park JT, Youn SH, Kim JW, Lee TY, Son HH

Protein microarray or protein chips is potentially powerful tools for analysis of protein-protein interactions. APin cDNA was previously identified and cloned from a rat odontoblast cDNA library. The purpose of...
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Aurora Kinase A Is a Prognostic Marker in Colorectal Adenocarcinoma

Koh HM, Jang BG, Hyun CL, Kim YS, Hyun JW, Chang WY, Maeng YH

BACKGROUND: Aurora kinase A (AURKA), or STK15/BTAK, is a member of the serine/threonine kinase family and plays important roles in mitosis and chromosome stability. This study investigated the clinical significance...
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