- Leukotriene C4 synthase promoter polymorphism in aspirin - induced asthma
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Cho JY, Lee SY, Han SA, Yoo SH, Kim SS, Park HS, Park JW, Hong CS, In KH
- KMID: 2054840
- J Asthma Allergy Clin Immunol.
- 1999 Aug;19(4):542-547.
BACKGROUND: Aspirin/NSAIDs can release cysteinyl-leukotriene (cys-LTs) into airways and precipitate asthmatic symptoms in aspirin - induced asthma(AIA). It has been reported that there is profound overexpression of LTC4 synthase in... -
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- Prevalence of aspirin sensitivity among asthmatic patients with mild to moderate severity and its clinical characteristics
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Lee JY, Kim TB, Sohn SW, Chang YS, Chung JW, Kim SH, Kim YK, Cho SH, Min KU, Kim YY
- KMID: 2285909
- J Asthma Allergy Clin Immunol.
- 2002 Mar;22(1):100-108.
BACKGROUND: While aspirin sensitivity has been known to be common among patients with severe asthma, its frequency among asthmatics with mild to moderate severity remains to be learned. OBJECTIVES: To elucidate... -
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- Protection of leukotriene receptor antagonist against aspirin-induced bronchospasm in asthmatics
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Park JS, Jang AS, Park SW, Lee YM, Uh ST, Kim YH, Cha JY, Park SM, Park CS
- KMID: 2260419
- Allergy Asthma Immunol Res.
- 2010 Jan;2(1):48-54.
- doi: 10.4168/aair.2010.2.1.48
PURPOSE: Leukotriene receptor antagonists (LTRAs) are used to treat aspirin-intolerant asthma (AIA); however, the protective effects of long-term LTRA administration against aspirin-induced bronchospasm have not been evaluated. OBJECTIVES: We investigated the... -
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- A case of disodium cromoglycate-induced bronchoconstriction in aspirin-sensitive asthma
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Hong CS, Park JW, Kim CW, Choi YH
- KMID: 2092971
- Korean J Allergy.
- 1997 Sep;17(3):325-331.
Disodium cromoglycate(DSCG) has been widely used in the treatment of bronchial asthma and has become the prophylactic drug of choice in patients with mild-to-moderate asthma, because it has anti-allergic, anti-inflammatory... -
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- Airway Responsiveness to Inhaled Aspirin is Influenced by Airway Hyperresponsiveness in Asthmatic Patients
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Kim S, Choi IS, Kim YJ, Kim CS, Han ER, Park DJ, Kim DE
- KMID: 1776613
- Korean J Intern Med.
- 2010 Sep;25(3):309-316.
- doi: 10.3904/kjim.2010.25.3.309
BACKGROUND/AIMS: Many patients with aspirin-induced asthma have severe methacholine airway hyperresponsiveness (AHR), suggesting a relationship between aspirin and methacholine in airway response. This study was performed to determine whether methacholine... -
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- Update on Recent Advances in the Management of Aspirin Exacerbated Respiratory Disease
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Palikhe NS, Kim JH, Park HS
- KMID: 1777085
- Yonsei Med J.
- 2009 Dec;50(6):744-750.
- doi: 10.3349/ymj.2009.50.6.744
Aspirin intolerant asthma (AIA) is frequently characterized as an aspirin (ASA)-exacerbated respiratory disease (AERD). It is a clinical syndrome associated with chronic severe inflammation in the upper and lower airways... -
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- Potential Association of DCBLD2 Polymorphisms with Fall Rates of FEV1 by Aspirin Provocation in Korean Asthmatics
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Park TJ, Kim JH, Park BL, Cheong HS, Bae JS, Pasaje CF, Park JS, Uh ST, Kim MK, Choi IS, Park CS, Shin HD
- KMID: 2157892
- J Korean Med Sci.
- 2012 Apr;27(4):343-349.
- doi: 10.3346/jkms.2012.27.4.343
Aspirin exacerbated respiratory disease (AERD) is a clinical syndrome characterized by chronic rhinosinusitis with nasal polyposis and aspirin hypersensitivity. The aspirin-induced bronchospasm is mediated by mast cell and eosinophilic inflammation.... -
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