- A Study on the Distributions of Paraoxonase Activity and the Factors affecting Paraoxonase Activity of a Rural opulation
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Song J, Park HB
- KMID: 2282471
- Korean J Prev Med.
- 1990 Jun;23(2):194-200.
The paraoxonase (E. C. 3.1.1.2.) is a major enzyme to detoxicate the organophosphorus and carbamate which are the most widely used as the agricultural spraying insecticides. To investigate the distributions... -
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- HDL-Associated Paraoxonase 1 as a Bridge between Postmenopausal Osteoporosis and Cardiovascular Disease
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Eren E, Ellidag HY, Aydin O, Yilmaz N
- KMID: 2172149
- Chonnam Med J.
- 2014 Dec;50(3):75-81.
- doi: 10.4068/cmj.2014.50.3.75
The association of postmenopausal osteoporosis (PMOP) with both atherosclerosis and vascular/valvular calcification is well known. Recently, ample evidence has suggested a common etiologic factor, namely, reduced HDL-associated paraoxonase 1 (PON1)... -
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- Paraoxonase Activity and Oxidative Status in Patients with Tinnitus
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Koç S, Akyüz S, Somuk BT, Soyalic H, Yılmaz B, Taskin A, Bilinc H, Aksoy N
- KMID: 2167662
- J Audiol Otol.
- 2016 Apr;20(1):17-21.
- doi: 10.7874/jao.2016.20.1.17
BACKGROUND AND OBJECTIVES: The aim of this study was to investigate serum paraoxanase-1 (PON) activity, total oxidant status (TOS), total antioxidant status (TAS), and the oxidative stress index (OSI) in... -
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- Genotype-phenotype Analysis of Paraoxonase 1 in Schizophrenic Patients Treated with Atypical Antipsychotics
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Pavăl D, Nemeş B, Rusu RL, Dronca E
- KMID: 2405231
- Clin Psychopharmacol Neurosci.
- 2018 Feb;16(1):32-38.
- doi: 10.9758/cpn.2018.16.1.32
OBJECTIVE: Recent studies suggest a possible involvement of low paraoxonase 1 (PON1) enzyme activities in the association between schizophrenia, treatment with atypical antipsychotics and increased cardiovascular (CVD) risk. In the... -
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- The Effect of Agoraphobia on Oxidative Stress in Panic Disorder
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Gul IG, Karlidag R, Cumurcu BE, Turkoz Y, Kartalci S, Ozcan AC, Erdemli ME
- KMID: 2316307
- Psychiatry Investig.
- 2013 Dec;10(4):317-325.
We aimed to investigate whether agoraphobia (A) in panic disorder (PD) has any effects on oxidative and anti-oxidative parameters. We measured total antioxidant capacity (TAC), paraoxonase (PON), arylesterase (ARE) antioxidant... -
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- Plasma Paraoxonase Activities in Type 2 Diabetes Mellitus
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Her GM, Bae HY, Lee BR
- KMID: 2331683
- J Korean Diabetes Assoc.
- 1998 Sep;22(3):403-409.
BACKGROUND: Human serum paraoxonase is physically associated with HDL and has been implicated in the detoxification of organophosphate and possibly in the prevention of LDL lipid peroxidation. The activities of... -
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- Total Serum Oxidant/Antioxidant Status and Arylesterase Activity in Recurrent Aphthous Stomatitis
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Akoglu G, Metin A, Kilinc F, Pektas SD, Isikoglu S, Akbas A, Sener S
- KMID: 2265864
- Ann Dermatol.
- 2013 Aug;25(3):273-277.
- doi: 10.5021/ad.2013.25.3.273
BACKGROUND: Recurrent aphthous stomatitis (RAS) is a chronic relapsing inflammatory disorder of the oral mucosa with unknown etiology. Oxidative stress (OS) is suggested to play a main role in the... -
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- Evaluation of Paraoxonase, Arylesterase and Malondialdehyde Levels in Schizophrenia Patients Taking Typical, Atypical and Combined Antipsychotic Treatment
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Güneş M, Camkurt MA, Bulut M, Demir S, Ibiloğlu , Kaya MC, Atlı A, Kaplan I, Sir A
- KMID: 2356158
- Clin Psychopharmacol Neurosci.
- 2016 Nov;14(4):345-350.
- doi: 10.9758/cpn.2016.14.4.345
OBJECTIVE: Human serum paraoxonase (PON1) prevents lipids from peroxidation and functions as an antioxidant mechanism. Malonyldialdehyde (MDA) is the final product of lipid peroxidation and can be used as an... -
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- A Study on Gene Frequency of Paraoxonase Gene 2 in Patients with Coronary Heart Disease
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Choi TY, Lee YK, Kim WB, Lee DW, Hyon MS, Seo SW, Kim SK, Kwon YJ
- KMID: 2031009
- Korean J Clin Pathol.
- 1999 Aug;19(4):420-424.
BACKGROUND: Recent studies have implicated paraoxonase (PON), an HDL-associated enzyme, in providing protection against LDL oxidation, thus affecting the risk of coronary heart disease in general population. Serum PON activity... -
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- Antioxidative Activity after Rosuvastatin Treatment in Patients with Stable Ischemic Heart Disease and Decreased High Density Lipoprotein Cholesterol
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Park DS, Yun KH, Park HY, Rhee SJ, Kim NH, Oh SK, Jeong JW
- KMID: 2344443
- Korean Circ J.
- 2016 May;46(3):309-314.
- doi: 10.4070/kcj.2016.46.3.309
BACKGROUND AND OBJECTIVES: The clinical significance of statin-induced high-density lipoprotein cholesterol (HDL-C) changes is not well known. We investigated whether rosuvastatin-induced HDL-C changes can influence the anti-oxidative action of high-density... -
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- Oxytocin Ameliorates Remote Liver Injury Induced by Renal Ischemia-Reperfusion in Rats
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Tas Hekimoglu A, Toprak G, Akkoc H, Evliyaoglu O, Ozekinci S, Kelle I
- KMID: 1429389
- Korean J Physiol Pharmacol.
- 2013 Apr;17(2):169-173.
- doi: 10.4196/kjpp.2013.17.2.169
Renal ischemia-reperfusion (IR) causes remote liver damage. Oxytocin has anti-inflammatory and antioxidant effects. The main purpose of this study was to evaluate the protective function of oxytocin (OT) in remote... -
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- Effect of short-term, high-dose methylprednisolone on oxidative stress in children with acute immune thrombocytopenia
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Cura M, Koç A, Aksoy N, Özdemir Z
- KMID: 2364317
- Blood Res.
- 2016 Dec;51(4):261-267.
- doi: 10.5045/br.2016.51.4.261
BACKGROUND: Immune thrombocytopenia (ITP) is the most common cause of acquired childhood thrombocytopenia and is characterized by increased immune-mediated destruction of circulating thrombocytes. Oxidative damage may be involved in ITP... -
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- Paraoxonase Polymorphisms and Leukoaraiosis
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Shin BS
- KMID: 2191915
- J Korean Neurol Assoc.
- 2009 Nov;27(4):337-344.
BACKGROUND: There is an inverse relationship between lesion extent and plasma levels of antioxidants for white-matter lesions (leukoaraiosis) that are visible on MRI. Paraoxonase (PON) has both antioxidative and antiatherosclerotic... -
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- The relationship of the Coronary Artery Disease and Paraoxonase Gene Polymorphism
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You KH, Kim SY, Kim HS, Sohn DW, Oh BH, Lee MM, Park YB, Choi YS, Lee YW
- KMID: 1558487
- Korean J Med.
- 1998 Dec;55(6):1022-1030.
OBJECTIVES: Paraoxonase is a high density lipoprotein (HDL)-associated enzyme, which has been implicated in preventing low density lipoprotein-cholesterol (LDL-C) from oxidation. The human paraoxonase gene is codominantly expressed as allele... -
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- Effect of Eicosapentaenoic Acid Supplementation on Paraoxonase 2 Gene Expression in Patients with Type 2 Diabetes Mellitus: a Randomized Double-blind Clinical Trial
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Golzari MH, Javanbakht MH, Ghaedi E, Mohammadi , Djalali M
- KMID: 2444235
- Clin Nutr Res.
- 2019 Jan;8(1):17-27.
- doi: 10.7762/cnr.2019.8.1.17
Type 2 diabetes mellitus (T2DM) is recognized as one of the most prevalent metabolic diseases, and it is mostly associated with oxidative stress, atherosclerosis and dyslipidemia. Paraoxonase 2 (PON2) due... -
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- Relationship of Polymorphisms in the Oxidative Stress Related Genes - Paraoxonase and p22phox - to Variant Angina and Coronary Artery Stenosis in Korean
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Cho YS, Choi JH, Zhang SY, Lee JH, Hwang KK, Kim HS, Oh BH, Lee MM, Park YB, Choi YS
- KMID: 2029612
- Korean Circ J.
- 2003 Feb;33(2):104-112.
- doi: 10.4070/kcj.2003.33.2.104
BACKGROUND AND OBJECTIVES: Oxidative stress plays an important role in the pathogenesis of coronary atherosclerosis and spasm. We investigated whether the polymorphisms in two oxidative stress-related genes, paraoxonase and p22phox,... -
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- Three Months Monitored Metabolic Fitness Modulates Cardiovascular Risk Factors in Diabetic Patients
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Cirilli I, Silvestri , Marcheggiani F, Olivieri F, Galeazzi R, Antonicelli R, Recchioni , Marcheselli F, Bacchetti , Tiano L, Orlando P
- KMID: 2466509
- Diabetes Metab J.
- 2019 Dec;43(6):893-897.
- doi: 10.4093/dmj.2018.0254
Cardiovascular diseases represent the leading cause of death and moderate physical exercise is associated with a reduction in cardiovascular risk. The aim of the study was to evaluate the correlation... -
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- Paraoxonase Genotypes of Korean Diabetic Patients with Coronary Artery Disease or Ischemic Stroke
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Kim WS, Kim YS, Kim SH, Paeng JR, Woo JT, Yang IM, Kim SW, Choi YK
- KMID: 2306342
- Korean J Med.
- 1998 Nov;55(5):874-880.
OBJECTIVES: Paraoxonase is a high-density-lipoprotein- associated enzyme capable of hydrolysing lipid peroxides. Thus it might protect lipoproteins from oxidation. It has two isoforms, which arise from a glutamine (A isoform)... -
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- Cigarette Smoking and Polymorphism of the Paraoxonase 1 Gene as Risk factors for Lung Cancer
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Lee CH, Lee KY, Hong YC, Choe KH, Kim YD, Kang JW, Kim H, Hong JS
- KMID: 2318617
- Tuberc Respir Dis.
- 2005 May;58(5):490-497.
BACKGROUND: The paraoxonase enzyme plays a significant role in the detoxification of various organophosphorous compounds in mammals, and paraoxonase (PON) 1 is one of the endogenous free-radical scavenging systems in... -
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- Association of Paraoxonase 1 (PON1) polymorphisms with osteoporotic fracture risk in postmenopausal Korean women
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Kim BJ, Kim SY, Cho YS, Kim BJ, Han BG, Park EK, Lee SH, Kim HY, Kim GS, Lee JY, Koh JM
- KMID: 1097264
- Exp Mol Med.
- 2011 Feb;43(2):71-81.
- doi: 10.3858/emm.2011.43.2.009
There is increasing evidence of a biochemical link between lipid oxidation and bone metabolism. Paraoxonase 1 (PON1) prevents the oxidation of low-density lipoprotein (LDL) and metabolizes biologically active phospholipids in... -
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