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Decreased Aquaporin 4 and 6 mRNAs in Patients With Chronic Otitis Media With Otorrhea

Kim JH, Kim SS, Kim YI, Jung SY, Kim SH, Yeo SG

OBJECTIVES: Aquaporins (AQPs) are integral membrane proteins engaged in the modulation of water homeostasis, but the roles they play in chronic otitis media (COM) have not been well investigated. Accordingly,...
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Tweety Homologs (TTYH) Freshly Join the Journey of Molecular Identification of the VRAC/VSOR Channel Pore

Okada Y

No abstract available.
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Persistent Malfunction of Glymphatic and Meningeal Lymphatic Drainage in a Mouse Model of Subarachnoid Hemorrhage

Pu T, Zou W, Feng W, Zhang Y, Wang L, Wang H, Xiao M

Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular event that often is followed by permanent brain impairments. It is necessary to explore the pathogenesis of secondary pathological damages in order to...
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An Anti-aquaporin 4 Positive Longitudinally Extensive Transverse Myelitis with Antecedent Necrotizing Pneumonia Associated with S. aureus

Jung BK, Kwon JA, Lee JM

A 53-year-old male patient presented with quadriparesis during pulmonological hospitalization for the treatment of S. aureus associated necrotizing pneumonia. He was diagnosed with the aquaporin-4 (AQP4) positive longitudinally extensive transverse...
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Recurrent Optic Neuritis as the Initial Symptom in Demyelinating Diseases

Falcão-Gonçalves AB, Bichuetti , de Oliveira EML

BACKGROUND AND PURPOSE: Optic neuritis (ON) is an inflammation of the optic nerve that can be recurrent, with unilateral or bilateral presentation. Diagnosing recurrent cases may be challenging. We aimed...
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Large-Scale in-House Cell-Based Assay for Evaluating the Serostatus in Patients with Neuromyelitis Optica Spectrum Disorder Based on New Diagnostic Criteria

Kim Y, Kim G, Kong BS, Lee JE, Oh YM, Hyun JW, Kim SH, Joung A, Kim BJ, Choi K, Kim HJ

BACKGROUND AND PURPOSE: The detection of aquaporin 4-IgG (AQP4-IgG) is now a critical diagnostic criterion for neuromyelitis optica spectrum disorder (NMOSD). To evaluate the serostatus of NMOSD patients based on...
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Time-Dependent Expression Patterns of Cardiac Aquaporins Following Myocardial Infarction

Zhang HZ, Kim MH, Lim JH, Bae HR

Aquaporins (AQPs) are expressed in myocardium and the implication of AQPs in myocardial water balance has been suggested. We investigated the expression patterns of AQP subtypes in normal myocardium and...
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Clinical Usefulness of Cell-based Indirect Immunofluorescence Assay for the Detection of Aquaporin-4 Antibodies in Neuromyelitis Optica Spectrum Disorder

Kang ES, Min JH, Lee KH, Kim BJ

BACKGROUND: The presence of antibodies to aquaporin-4 (AQP4) has been identified as a key characteristic of neuromyelitis optica spectrum disorder (NMOSD), an autoimmune inflammatory demyelinating central nervous system (CNS) disorder....
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Down-Regulation of Aquaporin 4 in the Lithium-Treated Rat Brain

Kim S, Jung YW

  • KMID: 2128894
  • Korean J Anat.
  • 2007 Dec;40(4):311-317.
Lithium has long been a primary drug used to treat bipolar mood disorder. Recently, in vivo and in vitro studies have demonstrated neuroprotective actions of lithium, even though therapeutic mechanisms...
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The Role of Aquaporin-4 in Cerebral Edema Formation after Focal Cerebral Ischemia in Rats

Song YJ, Bae HR, Ha SU, Huh JT

  • KMID: 2339860
  • J Korean Neurosurg Soc.
  • 2007 Jan;41(1):30-38.
OBJECTIVE: To elucidate the role of aquaporin-4(AQP4) in cerebral edema formation, we studied the expression and subcellular localization of AQP4 in astrocytes after focal cerebral ischemia. METHODS: Cerebral ischemia were induced...
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Altered Expression of Aquaporin 4 (AQP4) in Hippocampal Formation after Systemic Hyponatremia

Jung Y, Hong S

  • KMID: 2092862
  • Korean J Anat.
  • 2005 Oct;38(5):443-450.
The expression of aquaporin-4 (AQP4) protein, bi-directional water channel, in the blood-brain barrier of the hippocampal formation (HF) was studied in the rat to determine the role of AQP4 in...
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