J Korean Neurol Assoc.  2018 Aug;36(3):220-222. 10.17340/jkna.2018.3.17.

An Anti-aquaporin 4 Positive Longitudinally Extensive Transverse Myelitis with Antecedent Necrotizing Pneumonia Associated with S. aureus

Affiliations
  • 1Department of Neurology, Kyungpook National University Hospital, Daegu, Korea. azulmar@gmail.com

Abstract

A 53-year-old male patient presented with quadriparesis during pulmonological hospitalization for the treatment of S. aureus associated necrotizing pneumonia. He was diagnosed with the aquaporin-4 (AQP4) positive longitudinally extensive transverse myelitis from pons to T3 level. Despite the administration of intravenous methylprednisolone and plasma exchange with appropriate antibiotics, the patient's neurological condition deteriorated and he died. Our case implies that an S. aureus associated necrotizing pneumonia can trigger an AQP4 positive neuromyelitis optica spectrum disorder and contribute to the devastating course.

Keyword

Myelitis transverse; Aquaporin 4; Pneumonia necrotizing

MeSH Terms

Anti-Bacterial Agents
Aquaporin 4
Hospitalization
Humans
Male
Methylprednisolone
Middle Aged
Myelitis, Transverse*
Neuromyelitis Optica
Plasma Exchange
Pneumonia*
Pons
Quadriplegia
Anti-Bacterial Agents
Aquaporin 4
Methylprednisolone
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