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Conservative treatment for atypical endometrial hyperplasia: what is the most effective therapeutic method?

Kim MK, Seong SJ

No abstract available.
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Endocrine Therapy for Breast Cancer

Woo J, Lim W

Breast cancer is the second most common cancer in Korean women and its mortality rate has increased steadily. Although breast cancer is heterogeneous tumor, hormone receptor-positive tumors comprise about 75...
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Adjuvant Hormonal Therapy: Current Standard and Practical Issues

Park BW, Park HS

  • KMID: 2425142
  • J Breast Cancer.
  • 2010 Sep;13(3):242-249.
Adjuvant hormonal therapy is used as the first target-specific approach in curing breast cancers due to its high efficacy and mild side effects. Five years of tamoxifen therapy has been...
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Menopausal Symptoms and Associated Factors in Breast Cancer Patients Receiving Hormone Therapy

Kim Y, Min YH

PURPOSE: The purpose of this study was to identify the degree of menopause symptoms and associated factors in patients with breast cancer who were receiving hormone therapy. METHODS: Data were collected...
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Factors Influencing Distress in Premenopausal Patients with Breast Cancer Undergoing Endocrine Therapy

Kim J, Kang Y

PURPOSE: The purpose of this study was to investigate relationships among menopausal symptoms, functional status, and distress and to identify factors influencing distress in premenopausal breast cancer patients who had...
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Factors Influencing Quality of Life in Patients with Breast Cancer on Hormone Therapy

Hwang E, Yi M

PURPOSE: The purpose of the study was to identify degrees of pain, menopause symptoms, and quality of life, and to identify factors influencing quality of life of patients with breast...
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Safety of Megestrol Acetate in Palliating Anorexia-Cachexia Syndrome in Patients with Castration-Resistant Prostate Cancer

Hong S, Jeong IG, You D, Lee JL, Hong JH, Ahn H, Kim CS

There are concerns whether megestrol acetate (MA) stimulates the growth of prostate cancer in castration-resistant prostate cancer (CRPC). We evaluated the effect of cumulative doses of MA on the disease-specific...
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GnRH Agonist Therapy to Protect Ovarian Function in Young Korean Breast Cancer Patients

Park HJ, Koo YA, Im YH, Yoon BK, Choi D

The increased survival of patients with breast cancer has given rise to other problems associated with the complications of chemotherapy. One major complication is premature ovarian failure, an especially harmful...
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Pure red-cell aplasia and autoimmune hemolytic anemia in a patient with acute hepatitis A

Chang HJ, Sinn DH, Cho SG, Oh TH, Jeon TJ, Shin WC, Choi WC

Pure red cell aplasia (PRCA) and autoimmune hemolytic anemia (AIHA) have rarely been reported as an extrahepatic manifestation of acute hepatitis A (AHA). We report herein a case of AHA...
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Recent developments in systemic chemotherapy for hepatocellular carcinoma

Han CJ

Despite recent developments in various chemotherapeutic agents and the performing of numerous clinical trials, chemotherapy still produces unsatisfactory results in hepatocellular carcinoma due to poor clinical benefit compared with untreated...
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Therapeutic options for management of endometrial hyperplasia

Chandra V, Kim JJ, Benbrook D, Dwivedi A, Rai R

Endometrial hyperplasia (EH) comprises a spectrum of changes in the endometrium ranging from a slightly disordered pattern that exaggerates the alterations seen in the late proliferative phase of the menstrual...
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Long-term survival of patients with recurrent endometrial stromal sarcoma: a multicenter, observational study

Yamazaki H, Todo Y, Mitsube K, Hareyama H, Shimada C, Kato H, Yamashiro

OBJECTIVE: The aim of this study was to evaluate the clinical behavior and management outcome of recurrent endometrial stromal sarcoma (ESS). METHODS: A retrospective review of charts of 10 patients with...
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Conservative therapy with metformin plus megestrol acetate for endometrial atypical hyperplasia

Shan W, Wang C, Zhang Z, Gu C, Ning C, Luo X, Zhou Q, Chen X

OBJECTIVE: To compare the efficacy of metformin plus megestrol acetate (MA) with that of MA alone for treating endometrial atypical hyperplasia (EAH). METHODS: This pilot study included 16 EAH patients who...
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Change in Somatostatinergic Tone of Acromegalic Patients according to the Size of Growth Hormone-Producing Pituitary Tumors

Chin SO, Chon S, Hwang YC, Jeong IK, Oh S, Kim SW

The aim of this study was to investigate the relationship between somatostatinergic tone (SST) and the size of growth hormone (GH)-producing pituitary tumors. GH levels of 29 patients with newly...
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Feature of amenorrhea in postoperative tamoxifen users with breast cancer

Kim H, Han W, Ku SY, Suh CS, Kim SH, Choi YM

OBJECTIVE: Tamoxifen has been used to prevent the recurrence of breast cancer. However, tamoxifen-users frequently experience amenorrhea and it can be confused from that caused by other hormonal abnormalities. In...
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Fertility preserving treatment with hysteroscopic resection followed by progestin therapy in young women with early endometrial cancer

Falcone F, Laurelli G, Losito S, Di Napoli , Granata V, Greggi S

OBJECTIVE: To report our 15-year institutional experience of fertility-sparing treatment in young patients with early endometrial cancer (EC) treated by combined hysteroscopic resection and progestin therapy. METHODS: Twenty-eight patients (stage IA,...
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Efficacy of Androgen Deprivation Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer Receiving Docetaxel-Based Chemotherapy

Min K, Chung JW, Ha YS, Lee JN, Kim BS, Kim HT, Kim TH, Yoo ES, Kwon TG, Chung SK, Tanaka M, Egawa S, Kimura T, Choi SH

PURPOSE: The purpose of this study was to determine the comparative effectiveness of androgen deprivation therapy (ADT) combined with docetaxel (DTX)-based chemotherapy in Korean and Japanese castration-resistant prostate cancer (CRPC)...
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Expression of procaspase 3 and activated caspase 3 and its relevance in hormone-responsive gallbladder carcinoma chemotherapy

Maurya SK, Tewari M, Sharma B, Shukla HS

BACKGROUND/AIMS: The higher incidence of gallbladder cancer (GBC) in females has been accredited to the involvement of hormones. The clinical implications of sex hormone receptors in GBC are well established....
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GnRH Agonist Therapy in a Patient with Recurrent Ovarian Granulosa Cell Tumors

Kim HJ, Lee SC, Bae SB, Kwon KW, Kim CK, Lee NS, Lee KT, Won JH, Hong DS, Park HS

A 65-yr-old woman presented 17 yr status post-hysterectomy with bilateral ovarian salpingo-oophorectomy, attributable to ovarian cancer. She was admitted to our hospital, with multiple cystic liver masses and multiple large...
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Dilatation and curettage is more accurate than endometrial aspiration biopsy in early-stage endometrial cancer patients treated with high dose oral progestin and levonorgestrel intrauterine system

Kim DH, Seong SJ, Kim MK, Bae HS, Kim ML, Yun BS, Jung YW, Shim JY

OBJECTIVE: To determine whether less invasive endometrial (EM) aspiration biopsy is adequately accurate for evaluating treatment outcomes compared to the dilatation and curettage (D&C) biopsy in early-stage endometrial cancer (EC)...
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