- Antigen targeting to M cells for enhancing the efficacy of mucosal vaccines
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Kim SH, Jang YS
- KMID: 2155350
- Exp Mol Med.
- 2014 Mar;46(3):e85.
- doi: 10.1038/emm.2013.165
Vaccination is one of the most successful applications of immunology and for a long time has depended on parenteral administration protocols. However, recent studies have pointed to the promise of... -
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- Identification of Outer Membrane Vesicles Derived from Orientia tsutsugamushi
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Lee SM, Kwon HY, Im JH, Baek JH, Kang JS, Lee JS
- KMID: 2164469
- J Korean Med Sci.
- 2015 Jul;30(7):866-870.
- doi: 10.3346/jkms.2015.30.7.866
Orientia tsutsugamushi, a causative pathogen of Scrub typhus, is a gram-negative intracellular bacterium. Outer membrane vesicles (OMVs) are produced from the membrane of bacteria and play many roles related to... -
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- Evaluation of adjuvant effects of fucoidan for improving vaccine efficacy
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Kim SY, Joo HG
- KMID: 2164522
- J Vet Sci.
- 2015 Jun;16(2):145-150.
- doi: 10.4142/jvs.2015.16.2.145
Fucoidan is a sulfated polysaccharide derived from brown seaweed, including Fucus vesiculosus. This compound is known to have immunostimulatory effects on various types of immune cells including macrophages and dendritic... -
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- Reaction of the sera of the Korean children free from Hib invasive diseases against H. influenzae type B capsular polysaccharide antigen
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Kim KH, Kim DS, Park MS, Kim KT, Kim HS, Kim KH, Kwon OH
- KMID: 1422179
- J Korean Med Sci.
- 1994 Feb;9(1):1-8.
- doi: 10.3346/jkms.1994.9.1.1
The purpose of our experiment is to examine the level of anti-Haemophilus influenza polysaccharide antibody titer in the Korean population. Using ELISA, the level of Hib-PS antibodies in 384 infants... -
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- Comparative antibody response of five recombinant antigens in related to bacterial shedding levels and development of serological diagnosis based on 35 kDa antigen for Mycobacterium avium subsp. paratuberculosis
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Shin SJ, Yoo HS, McDonough , Chang YF
- KMID: 1120066
- J Vet Sci.
- 2004 Jun;5(2):111-117.
Eighty-five complex (85A, 85B and 85C), 35-kDa and superoxide dismutase (SOD) were cloned, expressed and purified as antigens in an enzyme-linked immunosorbent assay (ELISA) to compare the serological reactivity of... -
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- Bordetella bronchiseptica antigen enhances the production of Mycoplasma hyopneumoniae antigen-specific immunoglobulin G in mice
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Yim SH, Hahn TW, Joo HG
- KMID: 2412450
- J Vet Sci.
- 2017 Sep;18(3):327-332.
- doi: 10.4142/jvs.2017.18.3.327
We previously demonstrated that Bordetella (B.) bronchiseptica antigen (Ag) showed high immunostimulatory effects on mouse bone marrow cells (BMs) while Mycoplasma (M.) hyopneumoniae Ag showed low effects. The focus of... -
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- Regulatory T-cell vaccination independent of auto-antigen
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Pascual DW, Yang X, Holderness K, Jun S, Maddaloni , Kochetkova I
- KMID: 2155347
- Exp Mol Med.
- 2014 Mar;46(3):e82.
- doi: 10.1038/emm.2014.4
To date, efforts to treat autoimmune diseases have primarily focused on the disease symptoms rather than on the cause of the disease. In large part, this is attributed to not... -
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- Molecular cloning, purification and immunogenicity of recombinant Brucella abortus 544 malate dehydrogenase protein
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Reyes AW, Simborio H, Hop HT, Arayan LT, Kim S
- KMID: 2363344
- J Vet Sci.
- 2016 Mar;17(1):119-122.
- doi: 10.4142/jvs.2016.17.1.119
The Brucella mdh gene was successfully cloned and expressed in E. coli. The purified recombinant malate dehydrogenase protein (rMDH) was reactive to Brucella-positive bovine serum in the early stage, but... -
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- Efficacy of Purified Vi Polysaccharide Typhoid Vaccine
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Park JH, Hong JJ, Choi ES, Lee JW, Park JH
- KMID: 1095363
- J Vet Sci.
- 2002 Jun;3(2):67-70.
This experiment was conducted to assess the efficacy of typhoid vaccine newly produced by purifying Vi antigen of Salmonella typhi. With Karber method, LD50 of challenging organism (S. typhi ty2)... -
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- Clinical Evaluation of Rapid Diagnostic Test Kit Using the Polysaccharide as a Genus-Specific Diagnostic Antigen for Leptospirosis in Korea, Bulgaria, and Argentina
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Lee JW, Park S, Kim SH, Christova , Jacob P, Vanasco NB, Kang YM, Woo YJ, Kim MS, Kim YJ, Cho MK, Kim YW
- KMID: 2360040
- J Korean Med Sci.
- 2016 Feb;31(2):183-189.
- doi: 10.3346/jkms.2016.31.2.183
Leptospirosis, a zoonotic disease that is caused by many serovars which are more than 200 in the world, is an emerging worldwide disease. Accurate and rapid diagnostic tests for leptospirosis... -
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