- Successful management of maternal factor VII deficiency in a cesarean section
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Lee YJ, Ju DH, Yi SW, Lee SS, Sohn WS
- KMID: 1841544
- Obstet Gynecol Sci.
- 2014 Jul;57(4):314-317.
- doi: 10.5468/ogs.2014.57.4.314
Factor VII (FVII) deficiency is an infrequent hereditary bleeding disorder that can make excessive bleeding in surgical interventions, such as a postpartum hemorrhage in a cesarean section. Although a recombinant... -
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- In Vitro and in Vivo Comparison of Antifibirinolytic Activity of Aprotinin and Tranexamic Acid Using a Thromboelastographic Method in Rabbits
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Kim GS, Yang M, Cho HS, Cha SH, Kim JS, Park Q, Oh YS
- KMID: 2092036
- Korean J Anesthesiol.
- 2005 Aug;49(2):227-234.
- doi: 10.4097/kjae.2005.49.2.227
BACKGROUND: Aprotinin and tranexamic acid are commonly used antifibrinolytics during liver transplantation, or cardiac surgery. However, it is not clear which drug is more effective to ameliorate the fibrinolysis. The... -
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- Surgery in patients with congenital factor VII deficiency: A single center experience
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Kim SH, Park YS, Kwon KH, Lee JH, Kim KC, Yoo MC
- KMID: 1832107
- Korean J Hematol.
- 2012 Dec;47(4):281-285.
- doi: 10.5045/kjh.2012.47.4.281
BACKGROUND: Congenital factor VII (FVII) deficiency is a rare hemorrhagic disorder that can cause excessive bleeding during and after surgery in affected patients. The recombinant form of activated factor VII... -
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- Minimal Dose of Tranexamic Acid Is Effective in Reducing Blood Loss in Complex Spine Surgeries: A Randomized Double-Blind Placebo Controlled Study
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Shakeri M, Salehpour , Shokouhi G, Aeinfar K, Aghazadeh , Mirzaei F, Alavi SA
- KMID: 2430663
- Asian Spine J.
- 2018 Jun;12(3):484-489.
- doi: 10.4184/asj.2018.12.3.484
STUDY DESIGN: A randomized double-blind placebo controlled study. PURPOSE: In the present study, we aimed to assess the efficacy of tranexamic acid (TXA) in reducing blood loss after laminectomy and posterolateral... -
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- A study on changes of coagulation inhibitors and fibrinolysis inhibitors in patients with liver cirrhosis and hepatoma
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Park CJ, Cho HI, Kim SI
- KMID: 1421508
- J Korean Med Sci.
- 1991 Mar;6(1):1-6.
- doi: 10.3346/jkms.1991.6.1.1
The authors conducted an investigation focusing mainly on the activities of the inhibitory factors of the coagulation and fibrinolysis processes in 35 normal adults and 72 liver cirrhosis and/or hepatoma... -
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- A 45-Year-Old Man With Recurrent Dyspnea and Hemoptysis during Exercise: Exercise-Induced Pulmonary Hemorrhage/Edema
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Kim DS, Lee M, Kwon OJ, Jeong I, Son JW, Na MJ, Kwon SJ
- KMID: 2320710
- Tuberc Respir Dis.
- 2015 Oct;78(4):375-379.
- doi: 10.4046/trd.2015.78.4.375
A 45-year-old man presented with dyspnea and hemoptysis during exercise. A chest computed tomography (CT) revealed multifocal diffuse patchy ground glass opacity and interlobular septal thickening in both the lungs.... -
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- Predictors of Hematoma Enlargement in Patients with Spontaneous Intracerebral Hemorrhage Treated with Rapid Administration of Antifibrinolytic Agents and Strict Conservative Management
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Kim CH, Lee SW, Kim YH, Sung SK, Son DW, Song GS
- KMID: 2461117
- Korean J Neurotrauma.
- 2019 Oct;15(2):126-134.
- doi: 10.13004/kjnt.2019.15.e23
OBJECTIVE: Spontaneous intracerebral hemorrhage (ICH) is caused by the rupture of small blood vessels and other health problems. In ICH patients, hematoma enlargement is the most critical risk factor for... -
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- The effect of tranexamic acid used for spine surgery on blood loss and transfused volume
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Yoo TJ, Jeon SG, Lee S, Kim KM, Yon JH, Hong KH
- KMID: 1970952
- Anesth Pain Med.
- 2009 Apr;4(2):106-112.
BACKGROUND: In this randomized controlled study, we evaluate the effect of tranexamic acid on perioperative blood loss and transfused volume in patients undergoing spine surgery. METHODS: We enrolled and randomly allocated... -
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- Effective Regimen of Tranexamic Acid to Reduce Blood Loss and Homologous Transfusion in Patients Undergoing Cardiopulmonary Bypass
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Kwak YL, Nam SB, Kim JH, Han DW, Lim HK, Lee CS
- KMID: 2032419
- Korean J Anesthesiol.
- 1998 Mar;34(3):557-563.
- doi: 10.4097/kjae.1998.34.3.557
BACKGROUND: Substantial bleeding after cardiopulmonary bypass(CPB) complicates postoperative patients care. Recently, antifibrinolytic agents have been used as pharmacologic means of reducing blood loss and tranexamic acid(TA) has been known to... -
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- Comparison of Hemostatic Effects between Aprotinin and Tranexamic Acid during Open Heart Surgery in Adults
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Moon HS, Sung SW
- KMID: 2298916
- Korean J Anesthesiol.
- 1998 Jul;35(1):108-114.
- doi: 10.4097/kjae.1998.35.1.108
BACKGROUND: Antifibrinolytics such as aprotinin and tranexamic acid have been administered to reduce blood loss of cardiac surgery, but opinions differ regarding the efficacy of each drug. This study was... -
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- The Changes in Coagulation and Fibrinolytic Activities in Acute Myocardial Infarction Patients Treated with Recombinant Tissue Plasminogen Activator and Urokinase
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Seo J, Kim D, Kwon HM, Kim I, Jang Y, Kim HS, Song K
- KMID: 2229084
- Korean Circ J.
- 1998 May;28(5):700-706.
- doi: 10.4070/kcj.1998.28.5.700
BACKGROUND: The coagulation and fibrinolytic activities increase in the setting of acute myocardial infarction (AMI) and has been shown to increase further after the administration of thrombolytic agents. The reocclusion... -
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- Effectiveness and Safety of Tranexamic Acid in Spinal Deformity Surgery
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Choi HY, Hyun SJ, Kim KJ, Jahng TA, Kim HJ
- KMID: 2365590
- J Korean Neurosurg Soc.
- 2017 Jan;60(1):75-81.
- doi: 10.3340/jkns.2016.0505.004
OBJECTIVE: Spinal deformity surgery has the potential risk of massive blood loss. To reduce surgical bleeding, the use of tranexamic acid (TXA) became popular in spinal surgery, recently. The purpose... -
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- The Effect of Low Dose Aprotinin in Patients with Adolescent Idiopathic Scoliosis Undergoing Posterior Spinal Fusion
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Park HG, Yoo BH, Lee S, Yon JH, Hong KH
- KMID: 2263297
- Anesth Pain Med.
- 2008 Jul;3(3):178-182.
BACKGROUND: Aprotinin is a kallikrein inhibitor at high doses and a plasmin inhibitor at low doses. Low-dose aprotinin has been shown to reduce transfusion requirements in patients undergoing liver resection,... -
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- An Analysis of Factors Related to Rebleeding in Patients with Aneurysmal Subarachnoid Hemorrhage
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Lee CY, Yim MB, Suh IY, Kim IM, Son EI, Kim DW
- KMID: 2256023
- Korean J Cerebrovasc Dis.
- 2001 Mar;3(1):63-69.
OBJECTS: To assess risk factors related to the occurrence of rebleeding in patients with aneurysmal subarachnoid hemorrhage (SAH) who had been planned to the early surgery, this study was conducted... -
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- Efficacy of Topical Tranexamic Acid in Treatment of Melasma
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Yoo J, Ahn H, Kim MS, Jue MS, Choi KH
- KMID: 2386238
- Korean J Dermatol.
- 2017 Jun;55(5):283-289.
BACKGROUND: Tranexamic acid (TXA), a plasmin inhibitor, has been used orally or via intradermal injection to treat melasma; however, there are limited studies regarding efficacy and safety of topical application... -
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- Deep Vein Thrombosis in the Lower Extremities in Comatose Elderly Patients with Acute Neurological Diseases
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Yamada SM, Tomita Y, Murakami H, Nakane M
- KMID: 2374044
- Yonsei Med J.
- 2016 Mar;57(2):388-392.
- doi: 10.3349/ymj.2016.57.2.388
PURPOSE: Comatose elderly patients with acute neurological illness have a great risk of deep vein thrombosis (DVT). In this study, the incidence of DVT and the effectiveness of early initiation... -
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- Anti-tumor Effects of Growth Factor Inhibitors and Anti-metastatic Agents in Human Gastric Cancer Cell Lines
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Rha SY, Chung HC, Gong SJ, Chung HC, Kim JH, Roh JK, Min JS, Kim BS
- KMID: 1906170
- J Korean Cancer Assoc.
- 1997 Jun;29(3):391-403.
PURPOSE: For tumor growth, invasion and metastasis, a cascade of linked sequential biological events is essential; overproduction of growth factors, activation of proteolytic enzymes, induction of tumor angiogenesis, and enhanced... -
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- Differential Effect of Vitamin K and Vitamin D Supplementation on Bone Mass in Young Rats Fed Normal or Low Calcium Diet
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Iwamoto J, Takeda T, Ichimura S, Sato Y, Yeh JK
- KMID: 2428329
- Yonsei Med J.
- 2004 Apr;45(2):314-324.
The purpose of this study was to clarify the differential effect of vitamin K and vitamin D supplementation on bone mass in young rats fed a normal or low calcium... -
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- Korean Patients with Superwarfarin Intoxication and Their Outcome
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Hong J, Yhim HY, Bang SM, Bae SH, Yuh YJ, Yoon SS, Yoon HJ, Kim ST, Chi HS
- KMID: 1792899
- J Korean Med Sci.
- 2010 Dec;25(12):1754-1758.
- doi: 10.3346/jkms.2010.25.12.1754
This observational study aimed at evaluating recent superwarfarin intoxication of Korean patients. Ten patients were diagnosed as or highly suspicious for superwarfarin intoxication. Case report forms described by attending hematologists... -
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