- Commentary on "Effects of gonadotropin-releasing hormone agonist treatment on final adult height in boys with idiopathic central precocious puberty"
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Cheon CK
- KMID: 2523825
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):215-216.
- doi: 10.6065/apem.2120134edi01
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- Commentary on "Long-term outcomes of Graves’ disease in children and adolescents receiving antithyroid drugs"
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Kim M
- KMID: 2523826
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):217-217.
- doi: 10.6065/apem.2120143edi01
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- History of insulin treatment of pediatric patients with diabetes in Korea
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Kim JH, Shin CH, Yang SW
- KMID: 2523829
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):237-241.
- doi: 10.6065/apem.2142242.121
The year 2021 is the centennial of insulin discovery. The discovery of insulin changes diabetes mellitus from a death sentence to a manageable disease. It became a historical turning point... -
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- Balanced assessment of growth disorders using clinical, endocrinological, and genetic approaches
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Savage MO, Storr HL
- KMID: 2523827
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):218-226.
- doi: 10.6065/apem.2142208.104
Determining the pathogenesis of pediatric growth disorders is often challenging. In many cases, no pathogenesis is identified, and a designation of idiopathic short stature is used. The investigation of short... -
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- Recognition of the Y chromosome in Turner syndrome using peripheral blood or oral mucosa tissue
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Barbosa LG, Siviero-Miachon AA, Souza MA, Spinola-Castro AM
- KMID: 2523834
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):272-277.
- doi: 10.6065/apem.2142026.013
Purpose: Turner syndrome is defined as total or partial loss of the second sex chromosome in a phenotypically female patient. Due to the possibility of hidden mosaicism of fragments of... -
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- Pasireotide treatment for severe congenital hyperinsulinism due to a homozygous ABCC8 mutation
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Mooij CF, Tacke CE, van Albada ME, Barthlen W, Bikker H, Mohnike K, Oomen MW, van Trotsenburg AP, Zwaveling-Soonawala N
- KMID: 2523835
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):278-283.
- doi: 10.6065/apem.2142010.005
ABCC8 and KCJN11 mutations cause the most severe diazoxide-resistant forms of congenital hyperinsulinism (CHI). Somatostatin analogues are considered as secondline treatment in diazoxide-unresponsive cases. Current treatment protocols include the first-generation... -
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- Genotype - phenotype correlation in an adolescent girl with pathogenic PPARy genetic variation that caused severe hypertriglyceridemia and early onset type 2 diabetes
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Gutierrez Alvarez A, Yachelevich N, Kohn B, Brar PC
- KMID: 2523836
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):284-289.
- doi: 10.6065/apem.2142056.028
Severe hypertriglyceridemia (HTG) (>885 mg/dL) can be caused by familial partial lipodystrophy type 3 (FPLD3), an autosomal dominant disorder caused by loss of function of the peroxisome proliferator-activated receptor gamma... -
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- Long-term outcomes of Graves’ disease in children and adolescents receiving antithyroid drugs
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Rho JG, Kum CD, Seo YJ, Shim YS, Lee HS, Hwang JS
- KMID: 2523833
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):266-271.
- doi: 10.6065/apem.2040286.143
Purpose: Antithyroid drugs (ATDs) are primarily used as an initial treatment in pediatric patients with Graves’ disease (GD). We aimed to investigate the long-term outcomes in pediatric GD patients receiving... -
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- Identification of sphingosine 1-phosphate level and MAPK/ERK signaling in pancreatic β cells
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Park JH, Park KK, Choe JY, Jang KM
- KMID: 2523831
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):252-258.
- doi: 10.6065/apem.2040266.133
Purpose: Sphingosine kinase is a lipid kinase that phosphorylates sphingosine to generate sphingosine 1-phosphate (S1P). S1P regulates pancreatic islet β-cell endoplasmic reticulum stress and proliferation. Type 1 and type 2... -
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- Prader-Willi syndrome: an update on obesity and endocrine problems
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Kim SJ, Cho SY, Jin DK
- KMID: 2523828
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):227-236.
- doi: 10.6065/apem.2142164.082
Prader-Willi syndrome (PWS) is a rare complex genetic disorder that results from a lack of expression of the paternally inherited chromosome 15q11-q13. PWS is characterized by hypotonia and feeding difficulty... -
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- Association of fibroblast growth factor 21 with metabolic syndrome and endothelial function in children: a prospective cross-sectional study on novel biomarkers
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Domouzoglou EM, Vlahos AP, Cholevas VK, Papafaklis MI, Chaliasos N, Siomou E, Michalis LK, Tsatsoulis A, Naka KK
- KMID: 2523830
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):242-251.
- doi: 10.6065/apem.2040258.129
Purpose: Metabolic and cardiovascular disease prevention starting in childhood is critical for reducing morbidity later in life. In the present study, the association of novel biomarkers with metabolic syndrome (MS)... -
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- Effects of gonadotropin-releasing hormone agonist treatment on final adult height in boys with idiopathic central precocious puberty
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Cho AY, Ko SY, Lee JH, Kim EY
- KMID: 2523832
- Ann Pediatr Endocrinol Metab.
- 2021 Dec;26(4):259-265.
- doi: 10.6065/apem.2040268.134
Purpose: There are few reports on the therapeutic effects of gonadotropin-releasing hormone agonists in boys with central precocious puberty, and studies reported in Korea are very rare. We aimed to... -
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