- Alternative Splicing and Its Impact as a Cancer Diagnostic Marker
-
Kim YJ, Kim HS
- KMID: 2166488
- Genomics Inform.
- 2012 Jun;10(2):74-80.
- doi: 10.5808/GI.2012.10.2.74
Most genes are processed by alternative splicing for gene expression, resulting in the complexity of the transcriptome in eukaryotes. It allows a limited number of genes to encode various proteins... -
- CITED
-
- Close
- SHARE
-
- Close
- HExDB: Human EXon DataBase for Alternative Splicing Pattern Analysis
-
Park J, Lee M, Bhak J
- KMID: 1572678
- Genomics Inform.
- 2005 Sep;3(3):80-85.
HExDB is a database for analyzing exon and splicing pattern information in Homo sapiens. HExDB is useful for specific purposes: 1) to design primers for exon amplification from cDNA and... -
- CITED
-
- Close
- SHARE
-
- Close
- Investigation of Splicing Quantitative Trait Loci in Arabidopsis thaliana
-
Yoo W, Kyung S, Han S, Kim S
- KMID: 2366438
- Genomics Inform.
- 2016 Dec;14(4):211-215.
- doi: 10.5808/GI.2016.14.4.211
The alteration of alternative splicing patterns has an effect on the quantification of functional proteins, leading to phenotype variation. The splicing quantitative trait locus (sQTL) is one of the main... -
- CITED
-
- Close
- SHARE
-
- Close
- Identification of neoantigens derived from alternative splicing and RNA modification
-
Park J, Chung YJ
- KMID: 2462037
- Genomics Inform.
- 2019 Sep;17(3):e23.
- doi: 10.5808/GI.2019.17.3.e23
The acquisition of somatic mutations is the most common event in cancer. Neoantigens expressed from genes with mutations acquired during carcinogenesis can be tumor-specific. Since the immune system recognizes tumor-specific... -
- CITED
-
- Close
- SHARE
-
- Close
- Alternative splicing in 5'-untranslational region of STK-15 gene, encoding centrosome associated kinase, in breast cancer cell lines
-
Shin SO, Lee KH, Kim JH, Baek SH, Park JW, Gabrielson EW, Kwon TK
- KMID: 755098
- Exp Mol Med.
- 2000 Dec;32(4):193-196.
Centrosomes maintain genomic stability by establishing the bipolar spindles during cell division and, execute accurate segregation of chromosomes during mitosis. In this study, we have demonstrated that there... -
- CITED
-
- Close
- SHARE
-
- Close
- New Splicing Variants of the Murine Damaged DNA Binding 2
-
Park JH, Nam Y, Kwon J, Suh JG
- KMID: 1458945
- Lab Anim Res.
- 2010 Mar;26(1):91-94.
- doi: 10.5625/lar.2010.26.1.91
Damaged DNA binding (DDB) protein is an important gene in the repair of damaged DNA. DDB is a heterodimer (DDB1 and DDB2) protein, murine DDB2 has 10 exons about 1.5kb... -
- CITED
-
- Close
- SHARE
-
- Close
- Deducing Isoform Abundance from Exon Junction Microarray
-
Kim PR, Oh SJ, Lee SH
- KMID: 2166192
- Genomics Inform.
- 2006 Mar;4(1):33-39.
Alternative splicing (AS) is an important mechanism of producing transcriptome diversity and microarray techniques are being used increasingly to monitor the splice variants. There exist three types of microarrays interrogating... -
- CITED
-
- Close
- SHARE
-
- Close
- The effects of midazolam and sevoflurane on the GABAA receptors with alternatively spliced variants of the gamma2 subunit
-
Eom W, Lee JM, Park J, Choi K, Jung SJ, Kim HS
- KMID: 1766529
- Korean J Anesthesiol.
- 2011 Feb;60(2):109-118.
- doi: 10.4097/kjae.2011.60.2.109
BACKGROUND: Emergence agitation after sevoflurane anesthesia in children can be prevented by midazolam. Alternative splicing of the GABAA receptor changes with age. Therefore, we hypothesized that alternative splicing of the... -
- CITED
-
- Close
- SHARE
-
- Close
- Identification of Alternative Splicing and Fusion Transcripts in Non-Small Cell Lung Cancer by RNA Sequencing
-
Hong Y, Kim WJ, Bang CY, Lee JC, Oh YM
- KMID: 2320770
- Tuberc Respir Dis.
- 2016 Apr;79(2):85-90.
- doi: 10.4046/trd.2016.79.2.85
BACKGROUND: Lung cancer is the most common cause of cancer related death. Alterations in gene sequence, structure, and expression have an important role in the pathogenesis of lung cancer. Fusion... -
- CITED
-
- Close
- SHARE
-
- Close
- mTOR-coordinated Post-Transcriptional Gene Regulations: from Fundamental to Pathogenic Insights
-
Yeh HS, Yong J
- KMID: 2470798
- J Lipid Atheroscler.
- 2020 Jan;9(1):8-22.
- doi: 10.12997/jla.2020.9.1.8
Post-transcriptional regulations of mRNA transcripts such as alternative splicing and alternative polyadenylation can affect the expression of genes without changing the transcript levels. Recent studies have demonstrated that these post-transcriptional... -
- CITED
-
- Close
- SHARE
-
- Close
- Induction of Apoptosis by a Novel Bcl-2 Protein, Bak-like without a BH3 Domain
-
Ahn JY, Kim JK, Chung YS, Chung SS, Joo JY, Lee KS
- KMID: 2018693
- J Korean Neurosurg Soc.
- 2004 Feb;35(2):204-209.
OBJECTIVE: In a variety of physiologic settings, cells are eliminated by apoptosis, a genetically encoded process of cellular suicide. Bak, a member of the Bcl-2 protein family, accelerates apoptosis by... -
- CITED
-
- Close
- SHARE
-
- Close
- Scavenger Receptor Class A to E Involved in Various Cancers
-
Ryu S, Howland A, Song B, Youn C, Song PI
- KMID: 2468139
- Chonnam Med J.
- 2020 Jan;56(1):1-5.
- doi: 10.4068/cmj.2020.56.1.1
Scavenger receptors typically bind to multiple ligands on a cell surface, including endogenous and modified host-derived molecules and microbial pathogens. They promote the elimination of degraded or harmful substances such... -
- CITED
-
- Close
- SHARE
-
- Close
- Structure of human voltage-dependent calcium channel (VDCC) beta 3 subunit gene
-
Chang YJ, Cho KH, Hong YS, Lee SM, Kim HL
- KMID: 1532665
- Exp Mol Med.
- 1997 Dec;29(4):217-221.
In excitable and endocrine organs, calcium influxes through the voltage-dependent calcium channel (VDCC), composed of four (alpha 1, alpha 2, beta, and gamma) subunits. Four isoforms of beta subunits (beta... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of Exon 2 of Type II Procollagen mRNA in Primary Culture of Rat Chondrocyte
-
Kim TG, Seong IH, Kim ST, Kim HJ, Seong SC
- KMID: 2199181
- J Korean Orthop Res Soc.
- 1998 Oct;1(2):196-203.
Type II procollagen mRNA exists in two forms, type II A and II B, by alternative splicing of exon 2. Type II A procollagen mRNA has been known to be... -
- CITED
-
- Close
- SHARE
-
- Close
- A novel PRKAR1A mutation resulting in a splicing variant in a case of Carney complex
-
Jang YS, Moon SD, Kim JH, Lee IS, Lee JM, Kim HS
- KMID: 2381573
- Korean J Intern Med.
- 2015 Sep;30(5):730-734.
- doi: 10.3904/kjim.2015.30.5.730
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Temporal Patterns of Expression of Type II Procollagen Splice Forms During the Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells
-
Yoo JJ, Kim JW, Kim YM, Kim HJ
- KMID: 1848283
- J Korean Orthop Res Soc.
- 2004 Oct;7(2):133-144.
PURPOSE: We investigated the temporal patterns of expression of alternatively spliced Type II procollagen mRNAs during the chondrogenic differentiation of human bone marrow derived mesenchymal stem cells (hMSCs) in alginate... -
- CITED
-
- Close
- SHARE
-
- Close
- The role of soluble common gamma chain in autoimmune disease
-
Lee B, Hong C
- KMID: 2046070
- Anat Cell Biol.
- 2015 Mar;48(1):10-15.
- doi: 10.5115/acb.2015.48.1.10
The common gamma chain (gammac) is the central signaling unit for a number of cytokine receptors collectively known as the gammac cytokine receptor family. gammac is critical for ligand binding... -
- CITED
-
- Close
- SHARE
-
- Close
- Alternative Isoforms of TonEBP with Variable N-termini are Expressed in Mammalian Cells
-
Kim HS, Son SJ, Kim SN, Kim YD, Kim KJ, Jeon BH, Park JB, Lee SD
- KMID: 2285337
- Korean J Physiol Pharmacol.
- 2007 Jun;11(3):135-138.
Hypertonicity imposes a great deal of stress to cells since it causes rise in cellular ionic strength, which can be reduced by the accumulation of compatible osmolytes. TonEBP plays a... -
- CITED
-
- Close
- SHARE
-
- Close
- Immunohistochemical Study for CD44v6 in Hepatocellular Carcinoma and Cholangiocarcinoma
-
Yun KJ, Yoon KH, Han WC
- KMID: 2134350
- Cancer Res Treat.
- 2002 Jun;34(3):170-174.
PURPOSE: CD44 is a multifunctional adhesion molecule in cell-to-cell and cell-to-matrix interactions. This transmembrane glycoprotein exists in either standard or variant form, with the variation originating in alternative splicing. This... -
- CITED
-
- Close
- SHARE
-
- Close
- The Elevated Expression of the High Mobility Group-I(Y) Proteins in Thyroid Cancer using Semi-Quantitation RT-PCR
-
Ryu JW, Kim SJ
- KMID: 2206271
- J Korean Surg Soc.
- 1998 Jan;54(1):23-27.
High Mobility Group I(HMG-I) proteins are nuclear proteins that are required for induction of the human IFN-beta gene by virus and for the regulation of the tumor necrosis-beta factor and... -
- CITED
-
- Close
- SHARE
-
- Close
