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Renoprotective effects of febuxostat compared with allopurinol in patients with hyperuricemia: A systematic review and meta-analysis

Kim S, Kim HJ, Ahn HS, Oh SW, Han KH, Um TH, Cho CR, Han SY

BACKGROUND: Hyperuricemia is reported to be related to rapid progression of renal function in patients with chronic kidney disease (CKD). Allopurinol, a uric acid lowering agent, protects renal progression. However,...
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The potential renoprotection of xanthine oxidase inhibitors: Febuxostat versus allopurinol

Ryu DR

No abstract available.
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Comparative Efficacy and Safety of Febuxostat and Allopurinol in the Treatment of Hyperuricemia: A Bayesian Network Meta-analysis

Song GG, Lee YH

OBJECTIVE: The aim of this study was to assess the relative urate-lowering efficacy and safety of febuxostat and allopurinol in hyperuricemic patients with or without gout. METHODS: Randomized controlled trials (RCTs)...
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Treatment of Recalcitrant Acquired Reactive Perforating Collagenosis with Low-dose Allopurinol

Shin MS, Lee DR, Park MY

  • KMID: 2248798
  • Korean J Dermatol.
  • 2007 Nov;45(11):1230-1232.
Reactive perforating collagenosis is one of a range of essential perforating disorders and is characterized by the transepithelial elimination of altered collagen. Two types have been recognized: the inherited, or...
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Treatment of Acquired Perforating Dermatosis in Chronic Renal Failure with Allopurinol

Park HJ, Lee YS

  • KMID: 2302227
  • Korean J Dermatol.
  • 2007 May;45(5):509-511.
The perforating disorder is characterized by transepidermal elimination of altered dermal substances, which comprises Kyrle's disease, perforating folliculitis, elastosis perforans serpiginosa, and reactive perforating collagenosis. The term 'acquired perforating dermatosis'...
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Analysis of 13 Cases of Severe Drug Reactions due to Allopurinol

  • KMID: 2234389
  • Korean J Asthma Allergy Clin Immunol.
  • 2006 Sep;26(3):225-232.
BACKGROUND: Allopurinol-induced hypersensitivity reactions are rare but increasing recently in clinical practice; however, little has been known about its clinical characteristics and underlying mechanism. OBJECTIVE: The goal of this study was...
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Allopurinol Induced DRESS Syndrome in Patients with Chronic Kidney Disease

Lee SY, Kim NH, Jeong S, Jang DS, Lee YM, Na KR, Lee KW, Shin YT

  • KMID: 1597870
  • Korean J Nephrol.
  • 2006 Jul;25(4):681-687.
Allopurinol decreases serum uric acid levels in hyperuricemic patients and may slow the progression of renal diseases, Allopurinol-induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome, which was called...
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A Case of Allopurinol Hypersensitivity Syndrome with Esophageal Ulcer Bleeding

Kim JH, Song SH, Lee DW, Lee SB, Kwak IS

  • KMID: 1597867
  • Korean J Nephrol.
  • 2006 Jul;25(4):669-673.
Allopurinol, a commonly prescribed medicine for the management of gout and hyperuricemia, may induce life-threatening hypersensitivity characterized by fever, eosinophilia, hepatitis, renal failure, and skin eruptions such as Stevens-Johnson syndrome...
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5 Cases of Allopurinol Hypersensitivity Syndrome

  • KMID: 2299643
  • Korean J Asthma Allergy Clin Immunol.
  • 2006 Mar;26(1):83-88.
Allopurinol hypersensitivity syndrome is a rare, but life-threatening adverse reaction to allopurinol therapy. Clinically, it is characterized by multiple systemic abnormalities such as fever, rash, decreased renal function, hepa-tocellular injury,...
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The Mechanism of Damage to the Contralateral Testis Following Testicular Torsion and Detorsion in Rats and the Effect of Allopurinol Administration

Lim DJ, Hong SK, Jeong SJ, Choi H

PURPOSE: This study was performed to determine the mechanism of contralateral testis damage after repair of testicular torsion. In addition, we investigated the effect of allopurinol pretreatment on the contralateral...
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Two Cases of Allopurinol Hypersensitivity Syndrome in Patients Receiving Thiazide Therapy due to Hypertension

Song HJ, Kim CO, Lee KS

  • KMID: 2249390
  • Korean J Dermatol.
  • 2005 Oct;43(10):1426-1429.
Allopurinol hypersensitiviy syndrome (AHS) is a rare immunologic response to allopurinol, characterized by multiple findings such as skin rash, fever, hepatic dysfunction, decreased renal function, leukocytosis and eosinophilia. The risk...
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A Case of Allopurinol Hypersensitivity Syndrome in a Patient with Chronic Renal Failure

Kim MK, Yoo SH, Oh SS, Kim YS, Yoon SA, Kim YO, Chang YS, Kim JW

  • KMID: 2307249
  • Korean J Nephrol.
  • 2005 Sep;24(5):851-855.
Allopurinol hypersensitivity syndrome is a rare but life-threatening complication. We here report a case of allopurinol hypersensitivity syndrome manifested with irreVersible change of renal function and severe toxic epidermal necrolysis...
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Two Cases of Allopurinol Hypersensitivity Syndrome due to Use of Allopurinol for the Patient with Asymptomatic Hyperuricemia

Cho WI, Yoon YH, Kim MN, Seo SJ, Hong CK, Ro BI

  • KMID: 2302591
  • Korean J Dermatol.
  • 2005 Jul;43(7):961-964.
Allopurinol (4-hydroxypyrazolo[3, 4-d]pyrimidine) is a xanthine oxidase inhibitor and is widely used in the treatment of hyperuricemia. Allopurinol hypersensitivity syndrome (AHS) includes a prolonged illness initially manifested by fever, a...
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Two Cases of Allopurinol hypersensitivity syndrome

Park MW, Kim SS, Lee JJ

  • KMID: 2302747
  • Korean J Dermatol.
  • 2005 Jan;43(1):114-117.
Allopurinol hypersensitivity syndrome typically occurs in persons with preexisting renal failure, weeks to months after allopurinol is begun, the patient develops a generalized rash that often evolves to exfoliative erythroderma....
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The Effect of Doxorubicin and Allopurinol in Chemomyectomy

Jung WK, Ko HW, Kang DH, Koo SH, Park SH

  • KMID: 2322338
  • J Korean Soc Plast Reconstr Surg.
  • 2004 May;31(3):351-357.
This study was designed to identify doxorubicin as a permanent chemomyectomy agent that overcomes reversible effect of botulinum toxin A. Doxorubicin was assessed for its ability to bring about a...
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A Case of Allopurinol Hypersensitivity Syndrome

Jeon HJ, Bang HD, Kim KH, Kim KJ

Allopurinol is a xanthine oxidase inhibitor widely used to control plasma uric acid levels. Serious and life threatening adverse effects such as the allopurinol hypersensitivity syndrome(AHS) are rare. We describe...
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A Case of Allopurinol Hypersensitivity Syndrome

Kim BJ, Kim MN, Ro BI, Song KY

  • KMID: 2303041
  • Korean J Dermatol.
  • 2003 Feb;41(2):251-254.
Allopurinol(4-hydroxypyrazolo[3, 4-d]pyrimidine) is an analog of hypoxanthine, widely used in the treatment of gout and in some patients develop the allopurinol hypersensitivity syndrome. Allopurinol hypersensitivity syndrome is characterized by multiple...
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Effects of Oral Administration of Citrate, Thiazide, Allopurinol and Magnesium on Renal Calcium Oxalate Crystal Formation and Osteopontin Expression in a Rat Urolithiasis Model

Ahn SH, Kim JW, Moon YT, Lee TJ

  • KMID: 2293396
  • Korean J Urol.
  • 2003 Jan;44(1):87-94.
PURPOSE: It has previously been reported that citrate, thiazide, allopurinol and magnesium (CTAM) have inhibitory effects on calcium oxalate crystallization, but the effects of CTAM on the matrix proteins of...
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The Effect of Allopurinol Mucosal Painting in a Hamster of Oral Mucositis Induced by 5-Fluorouracil

Chu HR, Rho YS, Choi JO, Kim SJ

  • KMID: 1611642
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Dec;45(12):1172-1178.
BACKGROUND AND OBJECTIVES: 5-Fluorouracil (5-FU) is a commonly used drug in carcinomas of the head and neck. Mucositis and bone marrow toxicity are the two major side effects. Some initial...
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Effect of Saponin, Allopurinol and Nimodipine on Noise Induced Treshold Changes of ABRs in Guinea Pigs

Park YH, Min IK, Nam BH, Park CI

  • KMID: 2275945
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Aug;45(8):760-764.
BACKGROUND AND OBJECTIVES: Several studies have demonstrated that noise exposure may result in cochlear damage. The purpose of this study was to evaluate the effect of red Korean ginseng saponin...
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