Korean J Dermatol.
2007 May;45(5):509-511.
Treatment of Acquired Perforating Dermatosis in Chronic Renal Failure with Allopurinol
- Affiliations
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- 1Department of Dermatology, Ilsan Paik Hospital, Inje University School of Medicine, Ilsan, Korea. Stratum@medigate.net
Abstract
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The perforating disorder is characterized by transepidermal elimination of altered dermal substances, which comprises Kyrle's disease, perforating folliculitis, elastosis perforans serpiginosa, and reactive perforating collagenosis. The term 'acquired perforating dermatosis' has been suggested for cases associated with renal disease and/or diabetes mellitus. Recently, resolution of lesions in acquired reactive perforating collagenosis by allopurinol has been reported. We, hereby, report a patient with acquired perforating dermatosis associated with chronic renal failure due to diabetic nephropathy, who was treated with allopurinol. The histopathological findings were compatible with Kyrle's disease.