- Adoptive Transfer of Colon Cancer Derived Peptide-specific CD8+ T Cells in HHD Mice
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Jung HS, Ahn IS, Do HK, Lemonnier , Tirosh B, Tzehoval E, Vadai E, Eisenbach , Do MS
- KMID: 2054241
- Immune Netw.
- 2004 Mar;4(1):31-37.
- doi: 10.4110/in.2004.4.1.31
BACKGROUND: 1-8D gene is a member of human 1-8 interferon inducible gene family and is shown to be overexpressed in fresh colon cancer tissues. Three peptides 1-6, 3-5 and 3-7... -
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- Development of Auto Antigen-specific Regulatory T Cells for Diabetes Immunotherapy
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Song J
- KMID: 2355021
- Immune Netw.
- 2016 Oct;16(5):281-285.
- doi: 10.4110/in.2016.16.5.281
CD4⺠regulatory T cells (Tregs) are essential for normal immune surveillance, and their dysfunction can lead to the development of autoimmune diseases, such as type-1 diabetes (T1D). T1D is a... -
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- Role for CD40 and CD40L Expression in Generating CD8 T Cell Response to Minor Histcompatibility Antigen, H60
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Jung KM, Choi EY
- KMID: 2150634
- Immune Netw.
- 2007 Dec;7(4):173-178.
- doi: 10.4110/in.2007.7.4.173
BACKGROUND: We studied the role for expression of CD40 and CD40L by CD4 and CD8 T cells in the generation of CD8 T cell response to minor histocompatibility antigen, H60.... -
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- Adoptive transfer of Porphyromonas gingivalis heat shock protein epitope-specific T-cell lines into SCID mice in experimental atherosclerosis
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Choi J, Witztum J
- KMID: 1962388
- J Korean Acad Periodontol.
- 2005 Mar;35(1):1-8.
- doi: 10.5051/jkape.2005.35.1.1
Bacterial heat shock protein has been one of the components that are responsible to induce autoimmune disease mechanisms in the pathogenesis of atherosclerosis due to high level of homology in... -
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- The Kinetics of Secondary Response of Antigen-Specific CD4+ T Cells Primed in vitro with Antigen
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Park SO, Han YW, Aleyas AG, George JA, Yoon HA, Eo SK
- KMID: 2150619
- Immune Netw.
- 2006 Jun;6(2):93-101.
- doi: 10.4110/in.2006.6.2.93
BACKGROUND: Memory T lymphocytes of the immune system provide long-term protection in response to bacterial or viral infections/immunization. Ag concentration has also been postulated to be important in determining whether... -
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- Animal Models of Inflammatory Bowel Disease
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Jang BI
- KMID: 2174062
- Intest Res.
- 2008 Jun;6(1):8-18.
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of unknown etiology that includes two main disease entities-ulcerative colitis and Crohn's disease. Although the pathogenesis of IBD remains unclear, it... -
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- Efficient amplification of melanoma-specific CD8+ T cells using artificial antigen presenting complex
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Chang J
- KMID: 1115936
- Exp Mol Med.
- 2006 Dec;38(6):591-598.
In vitro large amplification of tumor-specific cytotoxic T lymphocytes (CTLs) and adoptive transfer of these cells is one of the most promising approaches to treat malignant diseases in which an... -
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- CD43 Expression Regulated by IL-12 Signaling Is Associated with Survival of CD8 T Cells
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Lee JB, Chang J
- KMID: 1456219
- Immune Netw.
- 2010 Oct;10(5):153-163.
- doi: 10.4110/in.2010.10.5.153
BACKGROUND: In addition to TCR and costimulatory signals, cytokine signals are required for the differentiation of activated CD8 T cells into memory T cells and their survival. Previously, we have... -
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- Extrinsic Acquisition of CD80 by Antigen-Specific CD8⺠T Cells Regulates Their Recall Immune Responses to Acute Viral Infection
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Son J, Ha SJ
- KMID: 2455935
- Immune Netw.
- 2019 Aug;19(4):e25.
- doi: 10.4110/in.2019.19.e25
CD80 is mainly expressed on Ag-presenting cells (APCs) as a costimulatory molecule but is also detected on T cells. However, the origin and physiological role of CD80 on CD8⺠T... -
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- Enhanced Anti-tumor Reactivity of Cytotoxic T Lymphocytes Expressing PD-1 Decoy
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Shin JH, Park HB, Choi K
- KMID: 2168054
- Immune Netw.
- 2016 Apr;16(2):134-139.
- doi: 10.4110/in.2016.16.2.134
Programmed death-1 (PD-1) is a strong negative regulator of T lymphocytes in tumor-microenvironment. By engaging PD-1 ligand (PD-L1) on tumor cells, PD-1 on T cell surface inhibits anti-tumor reactivity of... -
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- Enforced Expression of CXCR5 Drives T Follicular Regulatory-Like Features in Foxp3⺠T Cells
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Kim YU, Kim BS, Lim H, Wetsel RA, Chung Y
- KMID: 2375032
- Biomol Ther.
- 2017 Mar;25(2):130-139.
- doi: 10.4062/biomolther.2016.075
CXCR5⺠T follicular helper (Tfh) cells are associated with aberrant autoantibody production in patients with antibody-mediated autoimmune diseases including lupus. Follicular regulatory T (Tfr) cells expressing CXCR5 and Bcl6 have... -
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- Vaccinations with Dendritic Cells Can Elicit Preventive Immunity in a Squamous Cell Carcinoma Animal Model
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Son YI, Ko YJ, Chung SW, Lee CK
- KMID: 2276307
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Dec;47(12):1289-1296.
BACKGROUND AND OBJECTIVES: Dendritic cells (DC) can effectively mediate the prevention and regression of a variety of solid malignancies when they are properly primed with tumor antigens. However, little has... -
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- Current Perspectives on Emerging CAR-Treg Cell Therapy: Based on Treg Cell Therapy in Clinical Trials and the Recent Approval of CAR-T Cell Therapy
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Kang K, Chung J, Yang J, Kim H
- KMID: 2401566
- J Korean Soc Transplant.
- 2017 Dec;31(4):157-169.
- doi: 10.4285/jkstn.2017.31.4.157
Regulatory T cells (Treg) naturally rein in immune attacks, and they can inhibit rejection of transplanted organs and even reverse the progression of autoimmune diseases in mice. The initial safety... -
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- Cortical Bone Derived Stem Cells for Cardiac Wound Healing
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Mohsin S, Houser SR
- KMID: 2441134
- Korean Circ J.
- 2019 Apr;49(4):314-325.
- doi: 10.4070/kcj.2018.0437
Ischemic heart disease can lead to myocardial infarction (MI), a major cause of morbidity and mortality worldwide. Adoptive transfer of multiple stem cell types into failing human hearts has demonstrated... -
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- Targeting the epitope spreader Pep19 by naïve human CD45RA⺠regulatory T cells dictates a distinct suppressive T cell fate in a novel form of immunotherapy
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Kim HJ, Cha GS, Joo JY, Lee J, Kim SJ, Lee J, Park SY, Choi J
- KMID: 2392717
- J Periodontal Implant Sci.
- 2017 Oct;47(5):292-311.
- doi: 10.5051/jpis.2017.47.5.292
PURPOSE: Beyond the limited scope of non-specific polyclonal regulatory T cell (Treg)-based immunotherapy, which depends largely on serendipity, the present study explored a target Treg subset appropriate for the delivery... -
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- An Alternative Dendritic Cell-Induced Murine Model of Asthma Exhibiting a Robust Th2/Th17-Skewed Response
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Park SC, Kim H, Bak Y, Shim D, Kwon KW, Kim CH, Yoon JH, Shin SJ
- KMID: 2471235
- Allergy Asthma Immunol Res.
- 2020 May;12(3):537-555.
- doi: 10.4168/aair.2020.12.3.537
PURPOSE: Simple and reliable animal models of human diseases contribute to the understanding of disease pathogenesis as well as the development of therapeutic interventions. Although several murine models to mimic... -
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- Generation of CD2+CD8+ NK Cells from c-kit+ Bone Marrow Cells in Porcine
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Lim KH, Han JH, Roh YS, Kim B, Kwon JK, You MJ, Han HJ, Ejaz S, Kang CW, Kim JH
- KMID: 1768008
- Korean J Physiol Pharmacol.
- 2012 Jun;16(3):167-174.
- doi: 10.4196/kjpp.2012.16.3.167
Natural killer (NK) cells provide one of the initial barriers of cellular host defense against pathogens, in particular intracellular pathogens. Because bone marrow-derived hematopoietic stem cells (HSCs), lymphoid protenitors, can... -
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