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Heterogeneity of Adenosine Triphosphate-Based Chemotherapy Response Assay in Colorectal Cancer - Secondary Publication

Huh JW, Park YA, Lee KY, Sohn SK

PURPOSE: Adenosine triphosphate-based chemotherapy response assay (ATP-CRA) is a well-documented and validated technology that can individualize chemotherapy for patients with lung, stomach, or breast cancer. This study explored the feasibility...
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Impact of Grade, Hormone Receptor, and HER-2 Status in Women with Breast Cancer on Response to Specific Chemotherapeutic Agents by in vitro Adenosine Triphosphate-based Chemotherapy Response Assay

Koo JS, Jung W, Shin E, Lee HD, Jeong J, Kim KH, Jeong H, Hong SW

This study was designed to assess whether histological and biological factors of breast cancer can predict chemoresponse to specific agents. Adenosine triphosphate-based chemotherapy response assay (ATP-CRA) was employed to retrieve...
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ATP-Based Chemotherapy Response Assay in Primary or Recurrent Ovarian and Peritoneal Cancer

Lee M, Kim SW, Nam EJ, Cho H, Kim JH, Kim YT, Kim S

PURPOSE: To investigate chemosensitivity with an adenosine triphosphate-based chemotherapy response assay in patients with epithelial ovarian or peritoneal cancer according to tumor histology, grade, and disease status. MATERIALS AND METHODS: One...
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Complete Remission of Unresectable Colon Cancer after Preoperative Chemotherapy Selected by Adenosine Triphosphate-Based Chemotherapy Response Assay

Huh JW, Park YA, Jung EJ, Lee KY, Kwon JE, Sohn SK

The adenosine triphosphate-based chemotherapy response assay (ATP-CRA) is a chemosensitivity test that offers the potential of selecting cancer treatments based on the responsiveness of individual tumors. We report a case...
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ATP released from beta-amyloid-stimulated microglia induces reactive oxygen species production in an autocrine fashion

Kim SY, Moon JH, Lee HG, Kim SU, Lee YB

  • KMID: 1091077
  • Exp Mol Med.
  • 2007 Dec;39(6):820-827.
Present study demonstrated that fibrillar beta-amyloid peptide (fAbeta(1-42)) induced ATP release, which in turn activated NADPH oxidase via the P2X(7) receptor (P2X(7)R). Reactive oxygen species (ROS) production in fAbeta(1-42)-treated microglia...
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Computational Quantification of the Cardiac Energy Consumption during Intra-Aortic Balloon Pumping Using a Cardiac Electromechanics Model

Lim KM, Lee JS, Gyeong MS, Choi JS, Choi SW, Shim EB

To quantify the reduction in workload during intra-aortic balloon pump (IABP) therapy, indirect parameters are used, such as the mean arterial pressure during diastole, product of heart rate and peak...
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Characterization of cis-acting elements in the rat ATP citrate-lyase gene promoter

Moon YA, Park SW, Kim KS

  • KMID: 1093599
  • Exp Mol Med.
  • 2002 Mar;34(1):60-68.
The cis-acting element in the promoter of the rat ATP-citrate lyase (ACL) and transcription factors which interact with these elements were determined. Six Sp1 binding sites and CAAT box exist...
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ATP-induced focal adhesion kinase activity is negatively modulated by phospholipase D2 in PC12 cells

Bae YS, Ryu SH

  • KMID: 938879
  • Exp Mol Med.
  • 2001 Sep;33(3):150-155.
Extracellular ATP has been known to modulate various cellular responses including mitogenesis, secretion and morphogenic activity in neuronal cells. In the ATP-induced morphogenic activity, focal adhesion kinase(s) such as Fak...
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