- Expression of Cdx-2 Homeobox Gene in Intestinal Metaplasia and Gastric Adenocarcinoma
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Paik CH, Han DS, Lee SH, Chung YW, Kim JP, Sohn JH, Hahm JS, Oh YH, Park YU
- KMID: 1113418
- Korean J Gastroenterol.
- 2004 Oct;44(4):186-192.
BACKGROUND/AIMS: The Cdx-1 and Cdx-2 genes are intestinal transcription factors that may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. The Cdx-1 and Cdx-2... -
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- EGFR and KRAS Mutations in Patients With Adenocarcinoma of the Lung
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Jang TW, Oak CH, Chang HK, Suo SJ, Jung MH
- KMID: 1785642
- Korean J Intern Med.
- 2009 Mar;24(1):48-54.
- doi: 10.3904/kjim.2009.24.1.48
BACKGROUND/AIMS: Mutations of the epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) are important in the pathogenesis of lung cancer, and recent reports have revealed... -
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- p53 protein overexpression and allele loss of p53 gene in gastric adenocarcinoma
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Choi SW, Park WS, Yang JM, Kang CS, Sun HS, Kim BS, Seo EJ, Lee MJ, Park CS
- KMID: 644812
- J Korean Med Sci.
- 1994 Aug;9(4):299-303.
- doi: 10.3346/jkms.1994.9.4.299
Gene alterations of p53 tumor suppressor gene such as point mutations, deletions or insertions occur in various human cancers. p53 protein overexpression was studied immunohistochemically in 80 gastric adenocarcinomas using... -
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- The Role of Interleukin-1beta Gene Polymorphism in the Gastric Carcinogenesis
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Kang WK, Park WS, Chin HM, Park CH
- KMID: 1113294
- Korean J Gastroenterol.
- 2004 Jul;44(1):25-33.
BACKGROUND/AIMS: This study was aimed to investigate the polymorphism of interleukin-1beta(IL-1B) and IL-1 receptor antagonist (IL-1RN) gene and the relationship between genotypes and development of gastric adenocarcinoma in Korean,... -
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- Characterization of aberrant FHIT transcripts in gastric adenocarcinomas
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Lee SH, Kim CJ, Park HK, Koh JW, Cho MH, Baek MJ, Lee MS
- KMID: 938875
- Exp Mol Med.
- 2001 Sep;33(3):124-130.
Aberrant transcripts of FHIT (fragile histidine triad) have been reported in several types of primary tumors and cell lines, including gastric carcinoma. The role of these aberrant transcripts in tumorigenesis... -
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- A Gene Expression in Study Human Gastric Adenocarcinoma Using a cDNA Microarray
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Lee JH, Choi SR, Hwang TH, Kim MC, Jung GJ, Roh MS, Jeong JS
- KMID: 1066039
- Korean J Gastroenterol.
- 2003 Dec;42(6):484-495.
BACKGROUND/AIMS: cDNA microarray provides a powerful alternative with an unprecedented view scope in monitoring gene expression levels and leads to discoveries of regulatory pathways involved in complicated biological processes.... -
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- Characterization of Mutator Pathway in Younger-age-onset Colorectal Adenocarcinomas
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Roh SA, Kim HC, Kim JS, Kim JC
- KMID: 2157655
- J Korean Med Sci.
- 2003 Jun;18(3):387-391.
- doi: 10.3346/jkms.2003.18.3.387
The high-frequency microsatellite instability (MSI-H) phenotype, frequently identified in hereditary nonpolyposis colorectal cancer (HNPCC), also accounts for approximately 15% of sporadic colorectal cancers. Microsatellite instability (MSI) occurs from the mutational... -
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- Identification of CD44 splice variant in Korean colorectal cancers and cell lines
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Suh SI, Baek WK, Park JW, Bae OS, Suh MH, Choe BK
- KMID: 1054340
- J Korean Med Sci.
- 1995 Jun;10(3):169-175.
- doi: 10.3346/jkms.1995.10.3.169
CD44 is a glycoprotein expressed in a wide variety of cell types. Recently expression of some alternatively-spliced variants of CD44 transcripts (CD44v) has been suggested to play a potential role... -
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- Expression of Vascular Endothelial Growth Factor and p53 in Pancreatic Carcinomas
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Joo YE, Sohn YH, Lee WS, Park CH, Choi SK, Rew JS, Park CS, Kim SJ
- KMID: 759604
- Korean J Intern Med.
- 2002 Sep;17(3):153-159.
BACKGROUND: Angiogenesis has been shown to be a critical aspect of tumor growth and progression. Vascular endothelial growth factor (VEGF) has potent angiogenic activity and has been identified in... -
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- Detection of Rare Mutations in EGFR-ARMS-PCR-Negative Lung Adenocarcinoma by Sanger Sequencing
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Liang C, Wu Z, Gan X, Liu Y, You Y, Liu C, Zhou C, Liang Y, Mo H, Chen AM, Zhang J
- KMID: 2418843
- Yonsei Med J.
- 2018 Jan;59(1):13-19.
- doi: 10.3349/ymj.2018.59.1.13
PURPOSE: This study aimed to identify potential epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer that went undetected by amplification refractory mutation system-Scorpion real-time PCR (ARMS-PCR). MATERIALS... -
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- Genome-Wide Association Study of Lung Cancer in Korean Non-Smoking Women
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Kim JH, Park K, Yim SH, Choi JE, Sung JS, Park JY, Choi YY, Jeon HS, Park JY, Yoon HK, Kim YH, Yoo BS, Kim YT, Hu HJ, Chung YJ, Kim H, Sung SW, Hong YC
- KMID: 2158030
- J Korean Med Sci.
- 2013 Jun;28(6):840-847.
- doi: 10.3346/jkms.2013.28.6.840
Lung cancer in never-smokers ranks as the seventh most common cause of cancer death worldwide, and the incidence of lung cancer in non-smoking Korean women appears to be steadily increasing.... -
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- Prognostic Significance of Immunohistochemical Expression of p53 and Retinoblastoma Gene Protein (pRB) in Curatively Resected Gastric Cancer
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Song HS, Kim IH, Sohn SS, Kwon KY, Lee WS
- KMID: 1776689
- Korean J Intern Med.
- 2005 Mar;20(1):1-7.
- doi: 10.3904/kjim.2005.20.1.1
BACKGROUND: The aim of this study was to determine the prognostic significance of the expression of p53 and retinoblastoma (Rb) gene products in cases of curatively resected gastric adenocarcinoma, by... -
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