- The role of promoter methylation in Epstein-Barr virus (EBV) microRNA expression in EBV-infected B cell lines
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Kim DN, Song YJ, Lee SK
- KMID: 1015459
- Exp Mol Med.
- 2011 Jul;43(7):401-410.
- doi: 10.3858/emm.2011.43.7.044
Epstein-Barr virus (EBV) microRNAs (miRNAs) are expressed in EBV-associated tumors and cell lines, but the regulation mechanism of their expression is unclear yet. We investigated whether the expression of EBV... -
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- Genetic Susceptibility of Gastroduodenal Disease in Ethnic and Regional Diversity
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Lim YJ
- KMID: 2070070
- Gut Liver.
- 2014 Nov;8(6):575-576.
- doi: 10.5009/gnl14313
No abstract available. -
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- Investigation of -308G>A and -1031T>C Polymorphisms in the TNFA Promoter Region in Polish Peptic Ulcer Patients
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Salagacka , Zebrowska , Jelen A, Mirowski M, Balcerczak E
- KMID: 2070080
- Gut Liver.
- 2014 Nov;8(6):632-636.
- doi: 10.5009/gnl13224
BACKGROUND/AIMS: Tumor necrosis factor alpha (TNF-alpha) encoded by TNFA is a key mediator in inflammation, a precursor condition for peptic ulceration. Promoter polymorphisms of TNFA that influence its transcriptional activity... -
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- VEGF Promoter Polymorphism Confers an Increased Risk of Pulmonary Arterial Hypertension in a Chinese Population
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Zhuo Y, Zeng Q, Zhang P, Li G, Xie Q, Cheng Y
- KMID: 2427118
- Yonsei Med J.
- 2017 Mar;58(2):305-311.
- doi: 10.3349/ymj.2017.58.2.305
PURPOSE: Evidence on the contribution of genes to the hereditary predisposition to pulmonary arterial hypertension (PAH) is limited. MATERIALS AND METHODS: In this study, we hypothesized that single nucleotide variants in... -
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- Circadian regulation of low density lipoprotein receptor promoter activity by CLOCK/BMAL1, Hes1 and Hes6
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Lee YJ, Han DH, Pak YK, Cho S
- KMID: 1401756
- Exp Mol Med.
- 2012 Nov;44(11):642-652.
Low density lipoprotein receptor (LDLR) plays an important role in the cholesterol homeostasis. We examined the possible circadian regulation of LDLR and mechanism(s) underlying it. In mice, blood glucose and... -
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- Aberrant Hypomethylation of Solute Carrier Family 6 Member 12 Promoter Induces Metastasis of Ovarian Cancer
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Sung HY, Yang SD, Park AK, Ju W, Ahn JH
- KMID: 2374185
- Yonsei Med J.
- 2017 Jan;58(1):27-34.
- doi: 10.3349/ymj.2017.58.1.27
PURPOSE: Ovarian cancer (OC) is the most fatal of gynecological malignancies with a high rate of recurrence. We aimed to evaluate the expression of solute carrier family 6, member 12... -
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- Association of Polymorphisms in Monocyte Chemoattractant Protein-1 Promoter with Diabetic Kidney Failure in Korean Patients with Type 2 Diabetes Mellitus
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Moon JY, Jeong L, Lee S, Jeong K, Lee T, Ihm CG, Suh J, Kim J, Jung YY, Chung JH
- KMID: 1713285
- J Korean Med Sci.
- 2007 Oct;22(5):810-814.
- doi: 10.3346/jkms.2007.22.5.810
Monocyte chemoattractant protein-1 (MCP-1) is suggested to be involved in the progression of diabetic nephropathy. We investigated the association of the -2518 A/G polymorphism in the MCP-1 gene with progressive... -
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- The mitogen-activated protein kinase phosphatase-1 (MKP-1) gene is a potential methylation biomarker for malignancy of breast cancer
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Chen FM, Chang HW, Yang SF, Huang YF, Nien PY, Yeh YT, Hou MF
- KMID: 1383797
- Exp Mol Med.
- 2012 May;44(5):356-362.
The mitogen-activated protein kinase (MAPK) phosphatase-1 (MKP-1) belongs to the MAPK cascades which are central to cell proliferation and apoptosis. The carcinogenic role of MKP-1 has been reported in many... -
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- Secreted Phosphoprotein 1 Promoter Genetic Variants Are Associated with the Response to Pegylated Interferon alpha Plus Ribavirin Combination Therapy in Egyptian Patients with Chronic Hepatitis C Virus Infection
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Ali FT, Ali MA, Elgizawy M, Elsawy AM
- KMID: 2160636
- Gut Liver.
- 2015 Jul;9(4):516-524.
- doi: 10.5009/gnl14162
BACKGROUND/AIMS: The T-helper 1 (TH1) immune reaction is essential for the eradication of hepatitis C virus (HCV) during pegylated interferon alpha (PEG-IFN-alpha)- and ribavirin (RBV)-based therapy in chronic HCV patients.... -
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- Chromosomal Losses are Associated with Hypomethylation of the Gene-Control Regions in the Stomach with a Low Number of Active Genes
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Jung YC, Hong SJ, Kim YH, Kim SJ, Kang SJ, Choi SW, Rhyu MG
- KMID: 1107535
- J Korean Med Sci.
- 2008 Dec;23(6):1068-1089.
- doi: 10.3346/jkms.2008.23.6.1068
Transitional-CpG methylation between unmethylated promoters and nearby methylated retroelements plays a role in the establishment of tissue-specific transcription. This study examined whether chromosomal losses reducing the active genes in cancers... -
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