Korean J Hepatol.  2007 Sep;13(3):419-422. 10.3350/kjhep.2007.13.3.419.

A Case of Vasculitis in Chronic Hepatitis C Patient Treated with Pegylated Interferon Alpha-2a and Ribavirin

Affiliations
  • 1Department of Internal Medicine, Korea University Medical College, Guro Hospital, Seoul, Korea. je_yeon@hotmail.com

Abstract

There has been an increase in the number of patients treated with pegylated interferon (PEG-IFN) and ribavirin due to the better antiviral efficacy. The main serious adverse events of PEG-IFN plus ribavirin combination therapy are bone marrow suppression and hemolytic anemia. However, there are few reports of vasculitis occurring during PEG-IFN therapy. We describe a patient who developed vasculitis during the treatment of chronic hepatitis C with PEG-IFN and ribavirin.

Keyword

Hepatitis C, chronic; Peginterferon alfa-2a; Vasculitis; Skin

MeSH Terms

Antiviral Agents/*adverse effects
Drug Therapy, Combination
Female
Hepatitis C, Chronic/*drug therapy
Humans
Interferon Alfa-2a/*adverse effects
Liver Function Tests
Middle Aged
Polyethylene Glycols/*adverse effects
Ribavirin/*adverse effects
Skin/drug effects
Vasculitis/*chemically induced
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