J Korean Med Sci.  2003 Aug;18(4):599-602. 10.3346/jkms.2003.18.4.599.

Pulmonary Epithelioid Hemangioendothelioma: A Tumor Presented as a Single Cavitary Mass

Affiliations
  • 15th Criminal Division, Daegu District Public Prosecutor's Office, Daegu, Korea.
  • 2Department of Radiology, Chonbuk National University Medical School, Institute for Medical Sciences, Jeonju, Korea.
  • 3Department of Internal Medicine, Chonbuk National University Medical School, Institute for Medical Sciences, Jeonju, Korea.
  • 4Department of Pathology, Chonbuk National University Medical School, Institute for Medical Sciences, Jeonju, Korea. mjchung@moak.chonbuk.ac.kr

Abstract

Pulmonary epithelioid hemangioendothelioma (PEH) is a rare tumor that occurs among young women and typically presents as bilateral multiple nodules. In the present report, we describe an uncommon case of PEH presented as a single cavitary nodule in a 33-yr-old asymptomatic man. This is the first case of PEH presented as a single cavitary nodule in the English literature. Three years of the follow-up without treatment was performed. Overall histologic findings were accord with conventional PEH, but some atypical features such as, increased mitotic activity (mean; two per ten high power fields), necrosis, spindling, and pleural and vascular invasion were recognized. Immunohistochemically, the tumor cells were positive for CD34. This report may contribute to the data on clinical findings and natural history of this rare tumor.

Keyword

Lung; Hemangioendothelioma; Epithelioid

MeSH Terms

Adult
Antigens, CD34/biosynthesis
Hemangioendothelioma, Epithelioid/*diagnosis/pathology
Human
Immunohistochemistry
Lung Neoplasms/*diagnosis/pathology
Male
Mitosis
Necrosis
Time Factors
Tomography, X-Ray Computed
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