Tuberc Respir Dis.  2001 Nov;51(5):466-473. 10.4046/trd.2001.51.5.466.

A Case Pulmonary Epithelioid Hemangioendothelioma that Underwent Unusual Malignant Course

• Yoon HK
• Kim TY
• Jung JI
• Lee KY
• Moon HS
• Park SH
• Song JS

• KMID: 2160036
• DOI: http://doi.org/10.4046/trd.2001.51.5.466

Abstract

Pulmonary epithelioid hemangioendothelioma (PEH), originally termed an intravacular bronchioloalveolar tumor, is a rare pulmonary neoplasm with a vascular origin and slow rate of malignancy. It affects various organs such as the liver, the central nervous system, lung, etc. Clinically, pulmonary epithelioid hemangioendothelioma has been considered to be a borderline malignancy, a generally indolent and nonaggressive tumor that displaes the pulomonary parenchyma over a number of years by slowly enlarging the tumor nodule. The clinical course of PEH is known to be usually benign. Here we report an unusual case of PEH that was highly malignant and was eventually fatal. The PEH was confirmed by microscopic analysis and hmmunohistochemical staining of CD31+(a membrane receptor and a sensitive and specific marker for vascular lesions) from an open lung biopsy specimen.

Keyword

Pulmonary epithelioid hemangioendothelioma; Malignant course

MeSH Terms

Biopsy
Central Nervous System
Hemangioendothelioma, Epithelioid*
Liver
Lung
Lung Neoplasms
Membranes