Korean J Med.  2025 Apr;100(2):81-85. 10.3904/kjm.2025.100.2.81.

Diagnosis and Treatment of HER2-Positive Breast Cancer

Affiliations
  • 1Division of Hematology and Oncology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea

Abstract

Human epidermal growth factor receptor-2 (HER2)-positive breast cancer accounts for approximately 20% of all breast cancer cases. The advent of therapies targeting HER2 has significantly improved the prognosis for HER2-positive breast cancer. Neoadjuvant/adjuvant chemotherapy with HER2-targeted agents is recommended for early and locally advanced breast cancer. The appropriate use of novel HER2-targeted therapies is recommended for metastatic breast. We aimed to examine the diagnosis and personalized treatment for HER2-positive breast cancer.

Keyword

Breast neoplasms; HER2; Trastuzumab; Pertuzumab; Immunoconjugates; 유방암; HER2; 트라스투주맙; 퍼투주맙; 항체 약물 복합체
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