J Korean Med Assoc.  2024 Nov;67(11):679-685. 10.5124/jkma.2024.67.11.679.

Epidemiology and long-term effects of gestational diabetes mellitus

Affiliations
  • 1Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea
  • 2Department of Obstetrics and Gynecology, Keimyung University School of Medicine, Daegu, Korea

Abstract

Background
Gestational diabetes mellitus (GDM) is a prevalent metabolic disorder affecting 2.4%-22.3% of pregnancies, with notable regional variation. While most women with GDM return to normal glucose tolerance in the postpartum period, they remain at an increased risk of subsequent metabolic complications, such as type 2 diabetes mellitus, hypertension, and cardiovascular disease.
Current Concept
The prevalence of GDM has been increasing globally, including in Korea. Women diagnosed with GDM have an elevated risk of adverse outcomes during pregnancy, such as hypertensive disorders, cesarean sections, and fetal macrosomia. Additionally, GDM increases the long-term risks for type 2 diabetes mellitus, cardiovascular disease, and potentially liver disorders. The growing prevalence of GDM highlights the need for comprehensive surveillance and targeted interventions. Understanding the risk factors, such as lifestyle, ethnicity, maternal age, and pre-pregnancy obesity, is crucial to develop effective prevention and management strategies.
Discussion and Conclusion
Addressing the rising GDM trends requires public health efforts to monitor prevalence and mitigate risk factors through lifestyle modifications, early detection, and careful follow-up. Women with a history of GDM are at high risk for cardiometabolic diseases, necessitating proactive postpartum management including regular glucose monitoring and cardiovascular assessments. Establishing tailored preventive strategies and ensuring long-term follow-up for affected women may help reduce the burden of GDM and its associated complications, ultimately improving maternal health and quality of life.

Keyword

Gestational diabetes mellitus; Epidemiology; Cardiovascular diseases; Type 2 diabetes mellitus; Morbidity; 임신당뇨병; 역학; 심혈관질환; 제2형 당뇨병; 이환
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