J Korean Soc Radiol.  2024 Jul;85(4):785-788. 10.3348/jksr.2023.0130.

Mucin-Rich Brain Metastasis May Show the T2-FLAIR Mismatch Sign: A Case Report and Literature Review

Affiliations
  • 1Yonsei University College of Medicine, Seoul, Korea
  • 2Departments of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • 3Department of Neurosurgery, Brain Tumor Center, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • 4Departments of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea

Abstract

This study describes a unique case of single mucin-rich brain metastasis in a patient with breast cancer, mimicking the T2-fluid attenuation inversion recovery (FLAIR) mismatch sign and masquerading as an isocitrate dehydrogenase-mutant astrocytoma. This case highlights the importance of considering mucin-rich lesions in the differential diagnosis of intracranial tumors exhibiting T2-FLAIR mismatch. Clinicians must recognize the potential convergence in imaging characteristics between these metastases and gliomas to guarantee prompt and accurate patient care.

Keyword

Brain Metastasis; Glioma; T2-FLAIR Mismatch; Breast Cancer; Mucin
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