J Oral Med Pain.  2021 Sep;46(3):88-92. 10.14476/jomp.2021.46.3.88.

Acute Osteomyelitis of the Mandible by Extended-Spectrum ββ-Lactamase Producing Klebsiella Pneumoniae: A Case Report

• Jung GW
• Moon SY
• Oh JS
• Choi HI
• You JS

• KMID: 2552213
• DOI: http://doi.org/10.14476/jomp.2021.46.3.88

Abstract

Acute osteomyelitis caused by Klebsiella pneumoniae is rare in the oral and maxillofacial region. Klebsiella pneumoniae is a Gram-negative bacillus and the normal flora of the human body, but it can cause pneumonia, urinary tract infection, meningitis, and osteomyelitis in patient with compromised immune systems. These infections are mainly caused by nosocomial infection. Microbacterial osteomyelitis was developed by clinical cause such as tooth extraction, fracture, and surgical history, which requires long-term antibiotic administration and surgical treatment. This report describes that a 56-year-old male patient with acute osteomyelitis caused by Klebsiella pneumoniae infection after implant placement was treated with intravenous administration of ertapenem without open surgery treatment. Through this case, we report that antibiotic susceptibility test is essential for the treatment of acute osteomyelitis caused by a bacterial infection resistant to empirical antibiotics, and early administration of appropriate antibiotics can reduce the possibility of extensive bone destruction or additional open surgery.

Keyword

Antibiotics; Bacterial infection; Drug resistance; Klebsiella; Osteomyelitis