J Korean Orthop Assoc.  2023 Aug;58(4):311-320. 10.4055/jkoa.2023.58.4.311 .

Three-Dimensional Printing Technology Using Biomaterials for Bone Regeneration

Affiliations
  • 1School of Mechanical Engineering, Pusan National University, Busan, Korea

Abstract

Three-dimensional printing (3DP), or additive manufacturing, has attracted considerable attention for patient-specific medical applications. Among the standard technical groups, powder bed fusion (PBF) and material extrusion (ME) are preferred for fabricating metallic and polymeric medical implants, respectively. PBF-manufactured metallic implants, mainly from stainless steel, cobalt alloy, and titanium alloy, have shown clinical feasibility in a wide range of surgical applications owing to sufficient reliability of mechanical strength. The MEfabricated polymeric implants or scaffolds have some limitations in clinical use because of their inherently impaired strength. On the other hand, they are expected to overcome the limitations of metallic implants, such as a stress shielding effect and beam hardening artifact. Furthermore, the mechanical or biological functionality of polymeric materials can be enhanced by their composite materials with organic or inorganic fillers. Overall, with the advantage of customizing manufacturability, the 3DP technologies with biomaterials might meet the needs of patient-specific surgical applications, particularly in the case of bone regeneration.

Keyword

3D printing; prostheses and implants; bone regeneration; biocompatible materials
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