Korean J healthc assoc Infect Control Prev.  2023 Jun;28(1):99-105. 10.14192/kjicp.2023.28.1.99.

Efficacy of Disinfection Using Activated Ionized Hydrogen Peroxide System for Carbapenemase-producing Enterobacterales and Vancomycin Resistant Enterococci

• Lee KY
• Kang JY
• Choi UY
• Lee JH
• Ryu NH
• Hyun M
• Kim HA
• Lee JY

• KMID: 2543140
• DOI: http://doi.org/10.14192/kjicp.2023.28.1.99

Abstract

Background
Multidrug-resistant pathogens such as carbapenemase-producing Enterobacterales (CPE) and vancomycin-resistant enterococci (VRE) are of concern in hospitals worldwide. Hydrogen peroxide sterilizer is one of the ‘no-touch’ disinfection systems. In this study, we aimed to confirm the efficacy of the activated ionized hydrogen peroxide (AIHP) system space sterilizer developed in South Korea.
Methods
Eighty sheets contaminated with CPE and VRE were placed in each room. The AIHP space sterilizer (MUGYUN, SUNGSAM, Korea) was used for sterilization. After the intervention, the mediums were incubated at 37℃ for 24 h, and colony-forming units (CFUs) were analyzed.
Results
The median number of strains on the sheets before sterilization was 2.64×10⁶ CFUs (6.42 log₁₀ inoculum). The median log 10 reduction was 7.12 and 6.91 for CPE and VRE, respectively, after the intervention.
Conclusion
The AIHP space sterilizer developed in Korea was effective for the sterilization of VRE and CPE in the healthcare environment.

Keyword

Carbapenem-resistant enterobacteriaceae; Disinfection; Vancomycin-resistant enterococci

Figure

• 

  Fig. 1 Design of room showing positioning of AIHP space sterilizer, petri dishes and biological indicators. Abbreviations: AIHP, Activated Ionized Hydrogen Peroxide; CPE, Carbapenemase-producing Enterobacteriales; VRE, Vancomycin-resistant enterococci.

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