Clin Pediatr Hematol Oncol.  2023 Apr;30(1):25-29. 10.15264/cpho.2023.30.1.25.

Large Hepatocellular Adenoma Presenting with Iron Deficiency Anemia: A Case Report

Affiliations
  • 1Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Ulsan College of Medicine, Seoul, Korea
  • 2Department of Pediatric Surgery, Asan Medical Center Children’s Hospital, University of Ulsan College of Medicine, Seoul, Korea

Abstract

Hepatocellular adenoma is an uncommon, benign liver tumor usually occurring in patients using estrogen or anabolic androgens and in those with a genetic disease, including glycogen storage disease. Hepatocellular adenomas can sometimes induce pain. However, it is usually asymptomatic. Moreover, few studies have reported cases of hepatocellular adenomas presenting with iron deficiency anemia. Herein, we report a pediatric case of a large hepatocellular adenoma, presenting with iron therapy-refractory iron deficiency anemia. A 14-year-old boy was diagnosed with hepatocellular adenoma during an anemia work-up. Improvement in iron deficiency anemia was observed after tumor resection.

Keyword

Hepatocellular adenoma; Iron deficiency anemia; Hepcidins
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