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Large Hepatocellular Adenoma Presenting with Iron Deficiency Anemia: A Case Report

Koh YK, Yoon SH, Kang SH, Kim H, Im HJ, Ha S, Namgoong JM, Koh KN

Hepatocellular adenoma is an uncommon, benign liver tumor usually occurring in patients using estrogen or anabolic androgens and in those with a genetic disease, including glycogen storage disease. Hepatocellular adenomas...
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Recent Updates in Langerhans Cell Histiocytosis

Koh KN, Im HJ, Seo JJ

Langerhans cell histiocytosis (LCH) encompasses a wide range of clinical presentation and its clinical course varies widely from spontaneous regression to severe disseminated disease with the risk of permanent consequences....
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Meeting Report: The 3rd Seminar on Rare Pediatric Hematologic Disorders; Seoul; Korea; January 15, 2010

Koh KN, Kook H, Chung NG, Park CJ, Im HJ, Seo JJ

  • KMID: 2049261
  • Clin Pediatr Hematol Oncol.
  • 2010 Apr;17(1):84-86.
In January 2010, the Korean Society of Pediatric Hematology-Oncology and the Korea Histiocytosis Working Party organized "The 3rd Seminar on Rare Pediatric Hematologic Disorders" The seminar encompassed the updated issues...
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Improvement of Neurodegenerative Disease after Use of Vemurafenib in Refractory BRAF V600E-Mutated Langerhans Cell Histiocytosis: A Case Report

Koh YK, Yoon SH, Kang SH, Kim H, Im HJ, Kim PH, Jung AY, Koh KN

Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder characterized by heterogenous lesions infiltrated with CD1a+/CD207+ cells. Although LCH has a relatively good prognosis, the prognosis for patients with LCH...
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Favorable outcomes with durable chimerism after hematopoietic cell transplantation using busulfan and fludarabine-based reduced-intensity conditioning for pediatric patients with hemophagocytic lymphohistiocytosis

Suh JK, Koh YK, Kang SH, Kim H, Choi ES, Koh KN, Im HJ

Background The incorporation of a reduced-intensity conditioning (RIC) regimen in hematopoietic cell transplantation (HCT) for patients with hemophagocytic lymphohistiocytosis (HLH) has decreased early mortality but is associated with a high rate...
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Two Cases of Pediatric Collagenous Gastritis Each Presenting with Refractory Iron Deficiency Anemia and Chronic Diarrhea

Lee YJ, Kim KM, Oh SH, Song SM, Yu E, Koh KN

  • KMID: 2315339
  • Pediatr Gastroenterol Hepatol Nutr.
  • 2012 Sep;15(3):183-187.
Collagenous gastritis (CG) is a rare disorder that is characterized by the presence of a thick subepithelial collagen band with multiple infiltrated inflammatory cells of the gastric mucosa. CG is...
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Ten-Year Trends of Hematopoietic Stem Cell Transplantation in Korean Pediatric Cancer from the National Health Insurance Claims Data

Kim H, Kim HJ, Jo Y, Yoon SH, Koh YK, Kang S, Koh KN, Im HJ

Purpose We aimed to determine the current application and survival trends of hematopoietic stem cell transplantation (HSCT) among Korean children and adolescents with cancer. Materials and Methods Data of patients aged...
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Clinical characteristics and treatment outcomes of children and adolescents with aggressive mature B-cell lymphoma: a single-center analysis

Jeon W, Koh YK, Kang S, Kim H, Koh KN, Im HJ

Background Aggressive mature B-cell non-Hodgkin lymphoma (B-NHL) is the most common non-Hodgkin lymphoma in children. The outcome of chemotherapy for B-NHL has improved over decades. Methods We reviewed 82 children and adolescents with...
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Cell cycle regulators during human atrial development

Kim WH, Joo CU, Ku JH, Ryu CH, Koh KN, Koh GY, Ko JK

  • KMID: 759076
  • Korean J Intern Med.
  • 1998 Jul;13(2):77-82.
OBJECTIVES: The molecular mechanisms that regulate cardiomyocyte cell cycle and terminal differentiation in humans remain largely unknown. To determine which cyclins, cyclin dependent kinases (CDKs) and cyclin kinase inhibitors (CKIs)...
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Lineage Switch at Relapse of Childhood Acute Leukemia: A Report of Four Cases

Park M, Koh KN, Kim BE, Im HJ, Jang S, Park CJ, Chi HS, Seo JJ

Lineage switch in acute leukemia is an uncommon event at relapse, and therefore rarely reported in the literature. Here, we have described the clinical laboratory features of four cases in...
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Management of Hepatoblastoma in the Modern Era and Future Perspectives

Suh JK, Kang S, Kim H, Koh KN, Im HJ

Hepatoblastoma is the most common malignant hepatic tumor in infants and young children and accounts for approximately 1% of all pediatric malignancies. A treatment strategy incorporating chemotherapy and surgical resection...
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Successful Allogeneic Hematopoietic Stem Cell Transplantation for a Patient with Very Severe Aplastic Anemia During Active Invasive Fungal Infection

Seo E, Kim H, Koh KN, Im HJ, Seo JJ

Allogeneic hematopoietic stem cell transplantation (HSCT) may not be considered feasible in a patient with active fungal infection due to transplant-related mortality. We report a case of HSCT performed on...
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Recent advances in haploidentical hematopoietic stem cell transplantation using ex vivo T cell-depleted graft in children and adolescents

Im HJ, Koh KN, Seo JJ

Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for children and adolescents with various malignant and non-malignant diseases. While human leukocyte antigen (HLA)-identical sibling donor is the preferred...
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A Case of Pediatric Precursor B-cell Acute Lymphoblastic Leukemia Associated with Translocations (14;18)(q32;q21) and (8;9)(q24;p13)

Kim HJ, Kim H, Koh KN, Im HJ, Seo JJ, Seo EJ, Park CJ

Precursor B-cell acute lymphoblastic leukemia (ALL), which is the most common subtype of pediatric acute leukemia, generally has a good prognosis. However, the prognosis also depends on the genetic abnormalities...
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Isolated Pulmonary Langerhans Cell Histiocytosis in an Infant Diagnosed by CD1a Immunostaining of Bronchoalveolar Lavage Cells: A Case Report and Literature Review

Kim MJ, Yoo JH, Cho YW, Yoo JW, Kang SH, Kim H, Koh KN, Im HJ, Seo JJ

Isolated pulmonary Langerhans cell histiocytosis (LCH) is a very rare disease in childhood. We report a case of a 5-month-old girl with isolated pulmonary LCH, who was transferred due to...
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Improved outcome in childhood ALL with intensive consolidation and hematopoietic stem cell transplant

Park JA, Ghim T, Bae KW, Koh KN, Im HJ, Seo JJ

BACKGROUND: Despite advances in chemotherapy, the prognosis of relapsed acute lymphoblastic leukemia (ALL) remains poor. Few studies on relapsed ALL have reported the importance of intensive consolidation followed with or...
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Large Scale Single Deletion of Mitochondrial DNA in Chronic Progressive External Ophthalmoplegia

Koh KN, Park SY, Hwang H, Chae JH, Choi JE, Kim KJ, Hwang YS

  • KMID: 1582211
  • J Korean Child Neurol Soc.
  • 2004 May;12(1):43-49.
PURPOSE: Chronic progressive external ophtahlmoplegia(CPEO) is a common phenotype of mitochondrial myopathy. CPEO has wide clinical spectrum with variable severity and can be divided into 3 groups; Kearns-Sayre syndrome, ophthalmoplegia...
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Ketogenic Diet in Childhood Intractable Epilepsy

Koh KN, Park SY, Lim BC, Kang HS, Lee KY, Hwang H, Chae JH, Choi JE, Kim KJ, Hwang YS

  • KMID: 1582204
  • J Korean Child Neurol Soc.
  • 2004 May;12(1):12-20.
PURPOSE: Ketogenic diet(KD) is an alternative treatment for children with intractable seizures. This study was performed to evaluate the efficacy and tolerability of ketogenic diet METHODS: A retrospective study was performed...
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Prognostic factors of pediatric hematopoietic stem cell transplantation recipients admitted to the pediatric intensive care unit

Kim DH, Ha EJ, Park SJ, Koh KN, Kim H, Im HJ, Jhang WK

Background: Pediatric patients who received hematopoietic stem cell transplantation (HSCT) tend to have high morbidity and mortality. While, the prognostic factors of adult patients received bone marrow transplantation were already...
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Lupus Anticoagulant-hypoprothrombinemia Syndrome as an Initial Manifestation of Systemic Lupus Erythematosus: A Case Report

Sul Y, Lee JH, Park YS, Koh KN, Im HJ, Seo JJ

The lupus anticoagulant-hypoprothrombinemia syndrome, characterized by presence of lupus anticoagulant with acquired factor II deficiency, is a rare disease entity often presented with acute bleeding episodes. A 15-year-old girl was...
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