J Yeungnam Med Sci.  2023 Jan;40(1):4-11. 10.12701/jyms.2022.00010.

Beneficial effects of intermittent fasting: a narrative review

Affiliations
  • 1Department of Physiology & Obesity-mediated Disease Research Center, Keimyung University School of Medicine, Daegu, Korea
  • 2Department of Physiology, Yeungnam University College of Medicine, Daegu, Korea

Abstract

Caloric restriction is a popular approach to treat obesity and its associated chronic illnesses but is difficult to maintain for a long time. Intermittent fasting is an alternative and easily applicable dietary intervention for caloric restriction. Moreover, intermittent fasting has beneficial effects equivalent to those of caloric restriction in terms of body weight control, improvements in glucose homeostasis and lipid profiles, and anti-inflammatory effects. In this review, the beneficial effects of intermittent fasting are discussed.

Keyword

Caloric restriction; Diet therapy; Fasting; Obesity

Figure

  • Fig. 1. Possible mechanisms of intermittent fasting on health improvement. mTOR, mechanistic target of rapamycin; AMPK, AMP‐activated protein kinase; FOXO, forkhead box O; Redox, reduction-oxidation.


Reference

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