Perinatology.
2022 Dec;33(4):218-224. 10.14734/PN.2022.33.4.218.
Omphalocele–Exstrophy–Imperforate Anus–Spinal Defect Complex in an Infant from Monozygotic Twins Conceived by In Vitro Fertilization: A Case Report
- Affiliations
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- 1Departments of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea
- 2Departments of Obstetrics and Gynecology, Gachon University Gil Medical Center, Incheon, Korea
- KMID: 2537728
- DOI: http://doi.org/10.14734/PN.2022.33.4.218
Abstract
- The omphalocele–exstrophy–imperforate anus–spinal defect (OEIS) complex is a combination of congenital birth defects. This disease is rare and difficult to diagnose during pregnancy. However, if omphalocele, lumbosacral meningomyelocele, and difficulty in visualizing the bladder are observed on prenatal ultrasonography, the OEIS complex should be suspected. Prenatal diagnosis is important because this disease requires sophisticated multidisciplinary management to avoid excessive mor bidity. We report a prenatally suspected case of OEIS complex in a fetus of monozygotic twins con ceived by in vitro fertilization, which was later diagnosed after birth with omphalocele, bladder exstrophy, vesicointestinal fistula, imperforate anus, meningomyelocele, and club feet.
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