Korean J Obstet Gynecol.
2001 Jun;44(6):1201-1204.
A Case of Diamnionic Monochorionic Monozygotic Twin Which was Conceived by In Vitro Fertilization
- Affiliations
-
- 1Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University, Pocheon, Korea.
- 2Department of Genetics, College of Medicine, Pocheon CHA University, Pocheon, Korea.
- 3Department of Embryology, College of Medicine, Pocheon CHA University, Pocheon, Korea.
Abstract
-
Monozygotic twinning is a relatively rare event in vivo conception, being estimated to occur
in 0.42% of all birth. The underlying mechanism for monozygotic twin formation is the division
of the embryo early in its development. Separation of cells may theoretically occur before or
after inner cell mass formation. The incidence of monozygotic twinning following assisted
reproduction techniques is higher than the commonly accepted incidence after in vivo
conception. Patients at particular risk of monozygotic twins are those aged > 35 years
and those who had manipulation techniques for assisted fertilization. Hence, it seems
prudent to counsel these patients about the potential obstetric complications of monozygotic
multiple gestations prior to the initiation of their treatment.