Korean J Otorhinolaryngol-Head Neck Surg.  2022 Nov;65(11):722-726. 10.3342/kjorl-hns.2022.00360.

Acute Dizziness Treated With Thiamine Supplement: A Case of Wernicke Encephalopathy

• Kim B
• Hong SE
• Ahn J

• KMID: 2536189
• DOI: http://doi.org/10.3342/kjorl-hns.2022.00360

Abstract

Wernicke encephalopathy (WE) is an uncommon but severe neurological disorder caused by thiamine (vitamin B1) deficiency. It is characterized by the sudden onset of altered consciousness, ophthalmoplegia, and ataxia. Apart from chronic alcoholism, a lot of other conditions causing malnutrition and decreasing thiamine absorption must be considered as predisposing factors. Due to its low prevalence and clinical heterogeneity, WE is often misdiagnosed, resulting in persistent dysfunctions or death. Therefore, early diagnosis and prompt treatment with intravenous thiamine supplement might prevent encephalopathy and other neurologic or systemic complications of thiamine depletion. We hereby report of our experience of a WE patient who presented with predominantly vestibular symptoms and signs; the patient was successfully diagnosed and treated with high-dose intravenous thiamine repletion.

Keyword

Dizziness; Reflex, vestibulo-ocular; Thiamine; Wernicke encephalopathy