Korean J Geriatr Gerontol.  2017 Jun;18(1):48-51. 10.15656/kjcg.2017.18.1.48.

Alcoholic Wernicke Encephalopathy Presenting with Ataxic Gait and Diplopia

Affiliations
  • 1Departments of Family Medicine, Gachon University Gil Medical Center, Incheon, Korea
  • 2Departments of Neurology, Gachon University Gil Medical Center, Incheon, Korea
  • 3Departments of Radiology, Gachon University Gil Medical Center, Incheon, Korea

Abstract

Wernicke’s encephalopathy is an acute, reversible neurologic disorder which arises as metabolic complication of thiamine (vitamin B1) deficiency, frequently associated with alcohol misuse. Although Wernicke’s encephalopathy is characterized by a classic triad of mental status changes, ataxia, and ocular motor abnormalities, heterogenous clinical manifestations are more common. Prompt and accurate diagnosis by clinical suspicion is important to avoid death or progression to Korsakoff syndrome with irreversible brain damage. Immediate supplementation of thiamine is the cornerstone of treatment despite no accepted consensus on the optimal regimen. In this case report, we describe a case of Wernicke’s encephalopathy, which presentd with typical symtoms in a 63-year-old man with chronic alcoholism and review related literature.

Keyword

Wernicke encephalopathy; Alcohol-Related disorders; Thiamine deficiency
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