Pediatr Gastroenterol Hepatol Nutr.  2022 Nov;25(6):510-518. 10.5223/pghn.2022.25.6.510.

Effects of a Low-Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyol Diet on Symptoms of Functional Abdominal Pain in Pediatric Patients

• Abdou El Gendy YG
• Abdel Wahed MA
• Hassan Ragab MH
• Mohsen Awad YM

• KMID: 2535168
• DOI: http://doi.org/10.5223/pghn.2022.25.6.510

Abstract

Purpose
Recently, great interest has been focused on dietary fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) for the treatment of functional abdominal pain (FAP). Several meta-analyses, including those on the adult population, have been published, potentiating its role. However, pediatric studies are scarce. We aimed to evaluate the effect of a low-FODMAP diet on the severity of FAP in children.
Methods
This clinical trial included 50 patients aged 3–18 years with irritable bowel syndrome and FAP that were not otherwise specified. The patients were instructed to receive a low FODMAP diet guided by a dietitian. The primary outcome was the percentage of responders after 2 months of dietary intervention compared with baseline. Other outcomes included changes in stool consistency and quality of life (QoL) scores using the KIDSCREEN-10 questionnaire, and weight-for-age z-scores.
Results
After the dietary intervention, 74% of patients showed more than 30% lower pain intensity, as examined using the Wong-Baker Faces pain rating scale. Their QoL significantly improved, and patients have gained weight.
Conclusion
A low FODMAP diet can improve pain intensity and QoL among children with functional abdominal pain, with no detrimental effects on body weight.

Keyword

Child; Diet; Oligosaccharides; Disaccharides; Monosaccharides; Abdominal pain; Irritable bowel syndrome