J Pharmacoepidemiol Risk Manage.
2022 Sep;14(2):165-168. 10.56142/jperm.22.0013.
A Case of Atypical Fixed Drug Eruption Induced by Erdosteine
- Affiliations
-
- 1College of Pharmacy, Seoul National University, Seoul, Korea
- 2Seoul National University Hospital Drug Safety Monitoring Center, Seoul, Korea
- 3Seoul National University Hospital Regional Pharmacovigilance Center, Seoul, Korea
- 4Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
- KMID: 2534688
- DOI: http://doi.org/10.56142/jperm.22.0013
Abstract
- Erdosteine is a mucolytic agent used in acute and chronic respiratory disease and it is known to be well tolerated. Adverse drug reactions related with erdosteine are mostly mild gastrointestinal symptoms and only two case reports of hypersensitivity have been published. Here, we report a case of atypical fixed drug eruption related with erdosteine intake proven by a drug provocation test. Physicians should be aware of the hypersensitivity reaction related to erdosteine, despite its well-known tolerability.
