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A 10-Year Single-Center Experience of Adverse Drug Reaction Monitoring

Park SB, Moon M, Kim HH, Park GY, Kang DY, Lee JY, Cho YS, Kang HR, Cho SH

Background/Aims: Despite proper use of pharmaceuticals, adverse drug reactions (ADRs) can lead to problems related to patient safety. We analyzed the characteristics of ADRs, particularly serious adverse events (SAEs), in...
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Coronavirus disease 2019 vaccines and relevant adverse reactions

Chung EH

In order to overcome the global pandemic of the new pathogen, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), intensive research has been conducted to understand viral pathogenicity, establish effective treatment strategies, and...
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Colonic Perforation After Treatment With Nivolumab in Esophageal Cancer: A Case Report

Cho HJ, Kim WR, Kim JH, Kim DH, Kim DJ, Kang H

With the advent of checkpoint inhibitors, it has opened up opportunities for numerous cancer patients. However, as is the case with every treatment, complications need to be weighed. Gastrointestinal adverse...
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Pustular Eruption Induced by Adalimumab in a Patient with Ankylosing Spondylitis: A Case Report

Lim JH, Kwon SH, Sim WY, Lew BL

  • KMID: 2517082
  • Korean J Dermatol.
  • 2021 Jun;59(5):394-397.
Many cutaneous adverse reactions including eczematoid dermatitis and lichenoid eruption have been reported with the increased usage of tumor necrosis factor-α inhibitors. However, there are very few reports of generalized...
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Analysis of the Dermatologic Side Effects and the Factors Affecting the Efficacy of Immune Checkpoint Inhibitor in Melanoma: A Single-Center, Retrospective Study

Yoon D, Oh SJ, Kim HJ, Park JH, Lee JH, Lee DY, Lee JH

  • KMID: 2516137
  • Korean J Dermatol.
  • 2021 May;59(4):251-258.
Background: Programmed death 1 inhibitors enhance pre-existing immune responses by directly blocking anti-programmed cell death receptor-1. They have been widely used these days, but little is known about the dermatologic...
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Pulmonary toxicities of molecular targeted antineoplastic agents: a single-center 10-year experience

Lee MY, Yoon SY, Kim KH, Lee N, Kim HY, Hwang JH, Won JH

Background/Aims: A better understanding of cancer cell biology has led to the discovery and development of several new targeted agents for cancer. These drugs are widely used in cancer treatment...
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Diagnosis and treatment of drug-induced interstitial lung disease

Park S, Lee EJ

Drug-induced interstitial lung disease (DILD) is a group of adverse drug reactions that is rare but fatally toxic. Pulmonary toxicity causes inflammation and subsequent interstitial fibrosis. As novel drugs with...
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Delayed Onset of Manic Symptoms in a Patient with Influenza A (H1N1) after administration of Oseltamivir (Tamiflu): A Case Report

Jhon M, Kim JW, Kang HJ, Kim SY, Lee JY, Kim SW, Shin IS, Kim JM

Psychiatric side effects of oseltamivir can result in accident-proneness and suicide. Reportedly, such adverse psychiatric events are more common in children than in adults, but other risk factors are not...
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Safety of epidural steroids: a review

Lee MS, Moon HS

Spine disease is one of the most common musculoskeletal diseases, especially in an aging society. An epidural steroid injection (ESI) is a highly effective treatment that can be used to...
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Pretreatment screening and counseling on prolonged erections for patients prescribed trazodone

Shah T, Deolanker J, Luu T, Sadeghi-Nejad H

Purpose: We examined whether patients are appropriately screened for previous prolonged erections or priapism and counseled about trazodone complications, specifically prolonged erections and priapism, prior to trazodone treatment. Materials and Methods:...
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Drug-drug interactions with direct-acting antivirals — less is more

Wong GLH

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Patients’ perception about opioids and addiction in South Korea

Kim CL, Hong SJ, Lim YH, Jeong JH, Moon HS, Choi HR, Park SK, Kim JE, You H, Kim JH

Background: Chronic pain affects approximately 22% of the world’s population. Opioids can be useful in chronic pain management. However, some patients have negative perception of opioids. The purpose of this...
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Updates on Vaccine Safety and Post-Licensure Surveillance for Adverse Events Following Immunization in South Korea, 2005–2017

Yoon D, Kim JH, Lee H, Shin JY

Purpose: Vaccine hesitancy is among the top ten threats to global health, and access to precise data on adverse events following immunization (AEFIs) is imperative to alleviate public concerns surrounding...
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Analysis of Adverse Drug Reactions Identified in Nursing Notes Using Reinforcement Learning

Jeon E, Kim Y, Park H, Park RW, Shin H, Park HA

Objectives Electronic Health Records (EHRs)-based surveillance systems are being actively developed for detecting adverse drug reactions (ADRs), but this is being hindered by the difficulty of extracting data from unstructured records....
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The Characteristics of Adverse Drug Reactions in Cancer Patients: An Analysis of Spontaneously Reported Cases

Jeon HS, Kim HK, Choi GS

Background/Aims: Although the number of domestic adverse drug reactions (ADRs) reported in Korea is rapidly increasing, the analysis of ADRs in cancer patients remains limited. We sought to investigate the...
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Current Guidelines for Non-Steroidal Anti-Inflammatory Drugs

Park MG, Yoo JD, Lee KH

Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly used drugs worldwide for chronic pain, such as arthritis, and there are many different types depending on their composition and mechanism. After...
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Optimal Management of Chemotherapy-related Adverse Events

Jung MK

This review article deals with the optimal management of chemotherapy-related adverse events which are the nausea, vomiting, diarrhea, neutropenia, peripheral polyneuropathy. Recent literatures are reviewed and pathogenetic mechanism and management...
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Prediction of Drug–Drug Interactions by Using Profile Fingerprint Vectors and Protein Similarities

Dere S, Ayvaz S

OBJECTIVES: Drug–drug interaction (DDI) is a vital problem that threatens people's health. However, the prediction of DDIs through in-vivo experiments is not only extremely costly but also difficult as many...
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Efficacy and Tolerability of Low-Dose Perampanel in Patients with Childhood-Onset Intractable Epilepsy

Park H, Ahn H, Jang HN, Kim HJ, Yum MS, Ko TS

PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of perampanel as adjunctive therapy in childhood-onset refractory epilepsy. METHODS: We retrospectively reviewed the medical records of 110...
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Efficacy and Tolerability of Low-Dose Perampanel in Patients with Childhood-Onset Intractable Epilepsy

Park H, Ahn H, Jang HN, Kim HJ, Yum MS, Ko TS

PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of perampanel as adjunctive therapy in childhood-onset refractory epilepsy. METHODS: We retrospectively reviewed the medical records of 110...
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