Cardiovasc Imaging Asia.  2022 Apr;6(2):33-40. 10.22468/cvia.2021.00318.

Assessment of Left Ventricular Function and Regional Wall Motion by 256-Slice Dual-Source Coronary CT Angiography: A Comparison With 2D Transthoracic Echocardiography

• Thuy LLT
• Khoi VN
• Van HH
• Bao NP
• Ngoc TN
• Kim TVT
• Cong TN
• Anh PP
• Minh TP
• Dang LV

• KMID: 2529409
• DOI: http://doi.org/10.22468/cvia.2021.00318

Abstract

Objective
To compare left ventricular (LV) function, ejection fraction (EF), end-diastolic volume (EDV), end-systolic volume (ESV), and regional wall motion analyzed in 256-slice dualsource coronary CT angiography (DSCT) with 2D transthoracic echocardiography (TTE).
Materials and Methods
One hundred twelve patients suspected of coronary artery disease underwent DSCT and 2D-TTE within one week for LVEF, EDV, and ESV. The correlation between DSCT and 2D-TTE measurements was analyzed through linear regression and BlandAltman analysis. Regional wall motion was visually scored with a 3-point scale (1, normal; 2, hypokinesia; 3, dysphagia, akinesia).
Results
Average LVEF at 66.45%±1.27% (range 23%–85%) as determined on DSCT compared with 66.09%±1.01% (range 25%–84%) on 2D-TTE. LVEF exhibited a good correlation between DSCT and 2D-TTE (r=0.715; p<0.001). Good correlations between DSCT and 2D-TTE were demonstrated for LVEDV (r=0.732; p<0.001) and LVESV (r=0.841; p<0.001). Mean differences (±SD) of 1.78±24.10 mL (p<0.05) and 0.77±13.70 mL (p<0.05) were observed between DSCT and 2D-TTE for LVEDV and LVESV, respectively. LVEF was slightly overestimated with DSCT (0.52%±9.59%; p<0.05). Although the LVEF values calculated by DSCT and 2D-TTE were similar, EDV and ESV from DSCT were statistically higher than those from 2D-TTE (p<0.05). Agreement between DSCT and 2D-TTE in regional wall motion was 96.4%, κ=0.840.
Conclusion
DSCT can provide comparable results to those using 2D-TTE for LV function (EF, EDV, and ESV) and regional wall motion assessment in a heterogeneous population.

Keyword

Dual-source CT; Coronary artery disease; Left ventricular function; Echocardiography; Radiation